Results 111 to 120 of about 53,016 (292)

Ebola Virus L Polymerase RdRp Sequence and Phylogenetic Analysis [PDF]

open access: yesEgyptian Journal of Biomedical Engineering and Biophysics, 2019
Ebola Virus (EBOV) infection affects humans beings in the last four decades with the deadliest outbreak at 2015 in West Africa, leaving more than 10,000 deaths. The virus harms the liver of the patient when direct contact with contaminated body fluids or blood is occurred.
Mohamed El gohary   +3 more
openaire   +1 more source

Diazirines Beyond Photoaffinity Labeling: A Comprehensive Overview of Applications in Biological Sciences, Materials Chemistry, and NMR‐Spectroscopy

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Diazirines are three‐membered, nitrogen‐containing heterocycles that decompose under light or heat to generate carbenes. For the past two decades, they have served mainly as minimally invasive tags in photoaffinity labeling (PAL). More recently, their value as versatile carbene precursors has been recognized.
Dominik Schnalzer   +4 more
wiley   +2 more sources

Characterizing single-molecule dynamics of viral RNA-dependent RNA polymerases with multiplexed magnetic tweezers

open access: yesSTAR Protocols, 2022
Summary: Multiplexed single-molecule magnetic tweezers (MT) have recently been employed to probe the RNA synthesis dynamics of RNA-dependent RNA polymerases (RdRp).
Louis Kuijpers   +3 more
doaj   +1 more source

MicroRNA‐Induced Gene Silencing (MIGS): A Tool for Multi‐Gene Silencing and Targeting Viruses in Plants

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Since its discovery, RNA interference (RNAi, also known as gene silencing) has been a key tool to downregulate gene expression in plants for a range of applications, including protection against viruses. Many of these applications require the silencing of multiple genes concomitantly.
Marie‐Emilie A. Gauthier   +5 more
wiley   +1 more source

Detection and Characterization of Cucumis melo Cryptic Virus, Cucumis melo Amalgavirus 1, and Melon Necrotic Spot Virus in Cucumis melo

open access: yesViruses, 2019
Three RNA viruses—Cucumis melo cryptic virus (CmCV), Cucumis melo amalgavirus 1 (CmAV1), and melon necrotic spot virus (MNSV)—were identified from a melon (Cucumis melo) transcriptome dataset.
Binhui Zhan   +4 more
doaj   +1 more source

Tobamoviruses CP Proteins Hijack Light‐Induced Protein (NbLIP1) to Promote Viral Replication by Facilitating VRO Formation

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Tobamoviruses establish viral replication organelles (VROs) on the host endoplasmic reticulum (ER) for their replication, a process demanding substantial different types of lipids. However, how viruses efficiently transfer these lipids from other compartments like chloroplasts remains incompletely understood.
Haoyu Chen   +10 more
wiley   +1 more source

Inhibitory effect of lupeol, quercetin, and solasodine on Rhizopus oryzae: A molecular docking and dynamic simulation study

open access: yesJournal of Infection and Public Health, 2023
Background: Mucormycosis is an infection caused by fungi belonging to the order Mucorales. Rhizopus oryzae is one of the most prevalent organisms identified in mucormycosis patients.
Deepavalli Arumuganainar   +9 more
doaj   +1 more source

First Case of Systemic Coronavirus Infection in a Domestic Ferret (Mustela putorius furo) in Peru. [PDF]

open access: yes, 2015
A domestic ferret from Lima, Peru, died after ten days of non-specific clinical signs. Based on pathology, immunohistochemistry and molecular analysis, ferret systemic coronavirus (FRSCV)-associated disease was diagnosed for the first time in South ...
Gonzales-Viera, O   +5 more
core   +1 more source

Spatial Perturbations within an RNA Promoter Specifically Recognized by a Viral RNA-Dependent RNA Polymerase (RdRp) Reveal That RdRp Can Adjust Its Promoter Binding Sites [PDF]

open access: yesJournal of Virology, 1999
ABSTRACT RNA synthesis during viral replication requires specific recognition of RNA promoters by the viral RNA-dependent RNA polymerase (RdRp). Four nucleotides (−17, −14, −13, and −11) within the brome mosaic virus (BMV) subgenomic core promoter are required for RNA synthesis by the BMV RdRp (R. W. Siegel et al., Proc. Natl. Acad. Sci.
S S, Stawicki, C C, Kao
openaire   +2 more sources

Identification and sequence determination of a novel double-stranded RNA mycovirus from the entopathogenic fungus Beauveria bassina [PDF]

open access: yes, 2015
The final publication is available at Springer via https://doi.org/10.1007/s00705-014-2332-8.An isolate of the entomopathogenic fungus Beauveria bassiana was found to contain five double-stranded (ds) RNA elements ranging from 1.5 to more than 3 kbp. The
Coutts, Robert H.A.   +2 more
core   +1 more source

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