Results 131 to 140 of about 53,016 (292)

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Meeting review : ESF workshop on "Impact of nucleic acid chemistry on gene function analysis: antisense, aptamers, ribozymes and RNAi" [PDF]

, 2008
The shortage of functional information compared to the abundance of sequence information characterizes today’s situation in functional genomics. For many years the knock-down of a gene’s product has been the most powerful way of analysing its function ...
Engels, Joachim W. (Prof. Dr.), Heermeier, Kathrin, Prydz, Hans, Reinhard-Rupp, Jutta   +3 more
core  

Phosphorylation of TGB1 by protein kinase CK2 promotes barley stripe mosaic virus movement in monocots and dicots. [PDF]

, 2015
The barley stripe mosaic virus (BSMV) triple gene block 1 (TGB1) protein is required for virus cell-to-cell movement. However, little information is available about how these activities are regulated by post-translational modifications. In this study, we
Han, Chenggui, Hu, Yue, Jackson, Andrew, Jin, Xuejiao, Li, Dawei, Li, Zhenggang, Wang, Xianbing, Yan, Lijie, Yu, Jialin, Yuan, Cheng, Zhang, Yongliang, Zhao, Xiaofei   +11 more
core   +2 more sources

In silico Screening of Food Bioactive Compounds to Predict Potential Inhibitors of COVID-19 Main protease (Mpro) and RNA-dependent RNA polymerase (RdRp)

, 2020
As novel corona virus (COVID-19) infections has spread throughout the world, world health organization (WHO) has announced COVID-19 as a pandemic infection.
B. Pendyala, A. Patras
semanticscholar   +1 more source

Are Tetrapleura tetraptera Phytochemicals Druggable Against SARS‐CoV‐2 Papain‐Like Protein? A Computational Approach

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu   +1 more
wiley   +1 more source

Evidence for RNA recombination between distinct isolates of Pepino mosaic virus. [PDF]

, 2010
Genetic recombination plays an important role in the evolution of virus genomes. In this study we analyzed publicly available genomic sequences of Pepino mosaic virus (PepMV) for recombination events using several bioinformatics tools.
Hasiów-Jaroszewska, B., Kuzniar, A., Leunissen, J.A.M., Peters, S.A., Pospieszny, H.   +4 more
core   +1 more source

A non-canonical RNA silencing pathway promotes mRNA degradation in basal fungi [PDF]

, 2015
The increasing knowledge on the functional relevance of endogenous small RNAs (esRNAs) as riboregulators has stimulated the identification and characterization of these molecules in numerous eukaryotes.
A Dereeper, A Fire, A Gutierrez, A Velayos, AC Franken, Ana Vila, D Cifuentes, E Kiyota, F Hillmann, FE Nicolas, FE Nicolas, FE Nicolas, FE Nicolás, FE Nicolás, Francisco E. Nicolás, Geraldine Butler, H Lange, HC Lee, I Fierro-Monti, I Pócsi, IJ MacRae, J Sambrook, JE Stajich, JP de Haro, K Prufer, K Sorefan, LY Geer, M Cervantes, M Chayakulkeeree, M Ghildiyal, M Ha, M Thran, MD Quiles-Rosillo, N Akimitsu, NG Bologna, O Voinnet, P Comella, PU Christensen, R Aryal, R Parker, RC Edgar, Rosa M. Ruiz-Vázquez, S Calo, S Calo, S Cheloufi, S Gazzani, S Guindon, Santiago Torres-Martínez, SEJ Fischer, Silvia Calo, Simon Moxon, SS Chang, Tamas Dalmay, Trung Anh Trieu, V Garre, Victoriano Garre, W Hansberg, W Sun, Z Luo   +58 more
core   +3 more sources

Acid‐Promoted ROMP of a Pyridine‐Fused Norbornene Toward Main‐Chain Cationic Polymers

Macromolecular Chemistry and Physics, Volume 227, Issue 3, 16 February 2026.
Cationic polymers are valuable materials for applications ranging from biomedicine to ion transport. We report the ROMP of pyrido[2,3‐b]norbornadiene, a pyridine‐fused norbornene monomer, under acidic conditions. Protonation with HCl suppresses deleterious pyridine–Ru coordination, enabling controlled polymerization to afford well‐defined polymers with
An Tran, Vaishak Bhat, Quentin Michaudel
wiley   +1 more source

Template-directed biopolymerization: tape-copying Turing machines

, 2012
DNA, RNA and proteins are among the most important macromolecules in a living cell. These molecules are polymerized by molecular machines. These natural nano-machines polymerize such macromolecules, adding one monomer at a time, using another linear ...
Chowdhury, Debashish, Sharma, Ajeet K.
core   +1 more source

Molecular and phylogenetic characterization of honey bee viruses, Nosema microsporidia, protozoan parasites, and parasitic mites in China [PDF]

, 2008
China has the largest number of managed honey bee colonies, which produce the highest quantity of honey and royal jelly in the world; however, the presence of honey bee pathogens and parasites has never been rigorously identified in Chinese apiaries.
Yang, Bu, Peng, Guangda, Li, Tianbang, Kadowaki, Tatsuhiko   +3 more
core   +2 more sources