Results 141 to 150 of about 2,150 (202)

Effects of Air Temperature on Transient Expression of Influenza Hemagglutinin in Nicotiana benthamiana: Analysis of Transgene Transcription and Plant Stress Responses

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 5, Page 1142-1152, May 2025.
Effects on the number of days required to reach the maximum hemagglutinin (HA) content did not solely depend on the transgene transcript levels, regardless of the accumulation compartment. Effects on the reduction rate after the maximum HA content correlated with endoplasmic reticulum stress response, depending on the accumulation compartment ...
Patthasarun Pruksarojanakul   +4 more
wiley   +1 more source

Polyphenols as Potential Inhibitors of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp) [PDF]

open access: gold, 2021
Yifei Wu   +10 more
openalex   +1 more source

Photoinduced Cu(II)-Mediated RDRP to P(VDF-co-CTFE)-g-PAN [PDF]

open access: gold, 2018
Xin Hu   +4 more
openalex   +1 more source

In Silico Triple Targeting of SARS-CoV-2 3CLᵖʳᵒ, PLᵖʳᵒ, and RdRp by Philippine Antitubercular Natural Products Libraries [PDF]

open access: bronze, 2021
Jeremiah Gabriel Africa   +11 more
openalex   +1 more source

Effect of Substituents on the Tautomerism of Pyridone Nucleoside Analogs

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 14, April 7, 2025.
Experimental and quantum‐chemical work shows that the predominant tautomer of 6‐fluoropyridones is the lactim, not the lactam form. This makes them analogs of cytosine, not uracil or thymine in the context of incorporation opposite complementary bases of genetic sequences. Abstract Nucleobase analogs are important tools in medicine and chemical biology,
Leon Stark   +7 more
wiley   +1 more source

Effectiveness and Safety of Oral Azvudine for Elderly Hospitalized Patients With COVID‐19: A Multicenter, Retrospective, Real‐World Study

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This multicenter, retrospective, real‐world study enrolls the largest hospitalized elderly cohort of COVID‐19 patients from nine hospitals in Henan Province to investigate the effectiveness and safety of Azvudine. The results show that compared controls, Azvudine treatment can reduce the rate of all‐cause death in elderly patients with COVID‐19, and ...
Ranran Sun   +20 more
wiley   +1 more source

Higher mortality associated with the SARS-CoV-2 Delta variant in the Western Cape, South Africa, using RdRp target delay as a proxy: a cross-sectional study. [PDF]

open access: gold, 2022
Hannah Hussey   +24 more
openalex   +1 more source

qNMR quantification and in silico analysis of isobrucein B and neosergeolide from Picrolemma sprucei as potential inhibitors of SARS-CoV-2 protease (3CLpro) and RNA-dependent RNA polymerase (RdRp) and pharmacokinetic and toxicological properties

open access: gold, 2021
Marcos Túlio da Silva   +6 more
openalex   +2 more sources

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