Results 21 to 30 of about 1,080,370 (350)
On the Clinical Pharmacology of Reactive Oxygen Species [PDF]
Pharmacological Reviews, 2020 Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet clinical exploitation of these hypotheses by pharmacological modulation of ROS has been scarce to nonexistent. Are ROS, thus, irrelevant for disease? No. One key misconception in the ROS field has been its consideration as a rather detrimental metabolic by-product ...
Casas A. I. +15 more
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Generation of Reactive Oxygen Species by Mitochondria [PDF]
Antioxidants, 2021 Reactive oxygen species (ROS) are series of chemical products originated from one or several electron reductions of oxygen. ROS are involved in physiology and disease and can also be both cause and consequence of many biological scenarios. Mitochondria are the main source of ROS in the cell and, particularly, the enzymes in the electron transport chain
Hernansanz-Agustin, Pablo +1 more
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Mitochondria and reactive oxygen species [PDF]
Free Radical Biology and Medicine, 2009 Mitochondria are a quantitatively relevant source of reactive oxygen species (ROS) in the majority of cell types. Here we review the sources and metabolism of ROS in this organelle, including the conditions that regulate the production of these species, such as mild uncoupling, oxygen tension, respiratory inhibition, Ca2+ and K+ transport, and ...
Roger F. Castilho +3 more
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T cells and reactive oxygen species [PDF]
Journal of Biomedical Science, 2015 Reactive oxygen species (ROS) have been long considered simply as harmful by-products of metabolism, which damage cellular proteins, lipids, and nucleic acids. ROS are also known as a weapon of phagocytes, employed against pathogens invading the host.
Aleksey V. Belikov +2 more
openaire +3 more sources
Reactive Oxygen Species: Beyond Their Reactive Behavior [PDF]
Neurochemical Research, 2021 AbstractCellular homeostasis plays a critical role in how an organism will develop and age. Disruption of this fragile equilibrium is often associated with health degradation and ultimately, death. Reactive oxygen species (ROS) have been closely associated with health decline and neurological disorders, such as Alzheimer’s disease or Parkinson’s ...
Arnaud Tauffenberger +1 more
openaire +4 more sources
Vaccines, 2022 Heterologous immunization is garnering attention as a promising strategy to improve vaccine efficacy. Vaccines based on recombinant baculovirus (rBV) and virus-like particle (VLP) are safe for use, but heterologous immunization studies incorporating ...
Keon-Woong Yoon +8 more
doaj +1 more source
Recombinant AMA1 Virus-like Particle Antigen for Serodiagnosis of Toxoplasma gondii Infection
Biomedicines, 2022 Toxoplasmosis diagnosis predominantly relies on serology testing via enzyme-linked immunosorbent assay (ELISA), but these results are highly variable.
Min-Ju Kim +9 more
doaj +1 more source
Antioxidants, 2020 Global climate change and associated adverse abiotic stress conditions, such as drought, salinity, heavy metals, waterlogging, extreme temperatures, oxygen deprivation, etc., greatly influence plant growth and development, ultimately affecting crop yield
M. Hasanuzzaman +7 more
semanticscholar +1 more source
Clinical Characteristics and Short-term Outcomes of Acute Low Frequency Sensorineural Hearing Loss With Vertigo [PDF]
Clinical and Experimental Otorhinolaryngology, 2018 Objectives This study analyzed short-term prognosis in patients with acute low frequency hearing loss (ALHL), and also investigate hearing recovery rates in patients with ALHL accompanied vertigo.
Myung Jin Park +3 more
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Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.
Physiological Reviews, 2014 Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of potentially damaging levels of reactive oxygen species (ROS), Ca(2+), etc., which must be normalized.
D. Zorov, M. Juhaszova, S. Sollott
semanticscholar +1 more source