Results 71 to 80 of about 713,698 (263)

Reactive oxygen species and male reproductive hormones

Reproductive Biology and Endocrinology, 2018
Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential.
Mahsa Darbandi, Sara Darbandi, Ashok Agarwal, Pallav Sengupta, Damayanthi Durairajanayagam, Ralf Henkel, Mohammad Reza Sadeghi   +6 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Flow Cytometric Detection of Reactive Oxygen Species

Bio-Protocol, 2013
Reactive oxygen species (ROS) are molecules containing hydroxyl radicals or peroxides with unpaired electrons. In healthy aerobic cells, ROS are produced naturally as a byproduct of oxidative phosphorylation, oxidoreductase enzymes, or metal catalyzed ...
Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan   +5 more
doaj   +1 more source

Reactive oxygen species produced by myeloid cells in psoriasis as a potential biofactor contributing to the development of vascular inflammation [PDF]

, 2023
Theresa Schaller, Julia Ringen, Berenice Fischer, Tabea Bieler, Katharina Perius, Tanja Knopp, Katharina S. Kommoss, Thomas Korn, Mathias Heikenwälder, Matthias Oelze, Andreas Daiber, Thomas Münzel, Daniela Krämer, Philip Wenzel, Johannes Wild, Susanne Karbach, Ari Waisman   +16 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Nickel nanowires induced and reactive oxygen species mediated apoptosis in human pancreatic adenocarcinoma cells

International Journal of Nanomedicine, 2011
Md. Zakir Hossain1, Maurice G Kleve21Applied Biosciences (Bionanotechnology Research), Department of Applied Science, 2Molecular Biotechnology and Microscopy Laboratory, Department of Biology, University of Arkansas at Little Rock, Little Rock, Arkansas,
Kleve MG, Hossain MZ
doaj  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Cytotoxicity and reactive oxygen species generation from aggregated carbon and carbonaceous nanoparticulate materials

International Journal of Nanomedicine, 2008
Kristine M Garza1, Karla F Soto2, Lawrence E Murr31Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA; 2Lockheed Martin Aeronautics Company, Forth Worth, TX, USA; 3Department of Metallurgical and Materials Engineering,
Kristine M Garza, Karla F Soto, Lawrence E Murr   +2 more
doaj  

Enzymes That Scavenge Reactive Oxygen Species Are Down-Regulated Prior to Gibberellic Acid-Induced Programmed Cell Death in Barley Aleurone [PDF]

, 2001
Angelika Fath, Paul C. Bethke, Russell L. Jones   +2 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source