Results 41 to 50 of about 6,289 (112)

P023 | SETD2 loss in chronic myeloid leukemia promotes metabolic reprogramming and genomic instability leading to therapeutic resistance and disease progression

Haematologica
Chronic myeloid leukemia (CML) is driven by the Ph chromosome, but additional genetic abnormalities (AGAs) such as ASXL1 mutations and other cytogenetic alterations contribute to poor prognosis and reduced treatment response. SETD2 plays a critical role
Manuela Mancini
doaj  

The red blood cell proteome and interactome identify a Band 3-BLVRB axis regulating hypoxic metabolic adaptation. [PDF]

Blood
Issaian AV, Dzieciatkowska M, Bevers S, Safari Z, Hay AM, Cendali FI, Argabright A, Rogers SC, Saviola AJ, Redzic JS, Wartchow E, Reisz Haines J, Keele GR, Haiman ZB, Nemkov T, Stephenson D, Lisk C, Vallese F, Palsson BO, King SB, Page GP, Doctor A, Hudson KE, Hansen KC, Irwin DC, Mohandas N, Zimring JC, Eisenmesser EZ, D'Alessandro A.   +28 more
europepmc   +1 more source

When stress drives you to kidnap: RACK1A sequesters FSD1 into stress granules during salt stress. [PDF]

Plant Physiol
Selma S.
europepmc   +1 more source

Peroxisomal interactome mapping enables network-based modelling of function and disease. [PDF]

Life Sci Alliance
Gersting SW, Cramer JV, Guder P, Lotz-Havla AS, Wolf B, Noll-Puchta H, Erdmann R, Muntau AC, Woidy M.   +8 more
europepmc   +1 more source

A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseases. [PDF]

Cell Genom
Cox RM, Papoulas O, Shril S, Lee C, Gardner TP, Ansari ZT, Battenhouse AM, Lee M, Drew K, McWhite CD, Yang D, Leggere JC, Durand D, Hildebrandt F, Wallingford JB, Marcotte EM.   +15 more
europepmc   +1 more source

Beyond Hydrogen Sulfide and Cysteine Metabolism: Reframing Cystathionine γ-Lyase as a Potential Translational Regulator of Hypoxia-Inducible Factor-1α in Clear Cell Ovarian Carcinoma. [PDF]

Cells
El-Naggar AM.
europepmc   +1 more source

On the Feasibility of Clinical Studies with Cross-Linking Mass Spectrometry. [PDF]

J Proteome Res
Park SG, Ostrom EL, Liu S, Marcinek DJ, Bruce JE.   +4 more
europepmc   +1 more source

Deciphering the Neuroautophagic Interactome: Molecular Circuits Linking Selective Autophagy to Neuropathological Cascades in Neurological Disorders. [PDF]

Int J Biol Sci
Luo P, Travis ZD, Lenahan C, Wu H, Zhang J, Yu J, Xu W.   +6 more
europepmc   +1 more source

Proximity labeling in neuroscience: decoding molecular landscapes for precision neurology. [PDF]

Transl Neurodegener
Gao X, Lu J, Chen P, Wang X, Zheng L, Shao Y, Shen H, Yang Q.   +7 more
europepmc   +1 more source

SIRT3/AARS2 regulates SOD2 lactylation to determine neuronal fate in TBI. [PDF]

Mol Neurobiol
Song J, Liu J, Fan W, Gou F, Yang H, Wang P, Yang X, Tao K.   +7 more
europepmc   +1 more source