Results 21 to 30 of about 4,838,205 (202)

Redox signaling and metabolism in Alzheimer's disease

Frontiers in Aging Neuroscience, 2022
Reduction and oxidation reactions are essential for biochemical processes. They are part of metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second messengers and oxidative modifications of cysteinyl (Cys) residues are key to ...
M. I. Holubiec, M. Gellert, E. M. Hanschmann   +2 more
doaj   +1 more source

The Reactive Species Interactome - Mitochondria Axis

, 2022
From oxidative eustress and distress, to bioenergetic metabolism, and cell death, the reactive species interactome (RSI) and mitochondria are two connected metabolisms that require further investigation improving redox medicine. The step before, finding new clues needs a comprehensive discussion of the two metabolisms, and their relationship. Here, the
openaire   +1 more source

Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?

Redox Biology, 2019
The chemical and functional interactions between Reactive Oxygen (ROS), Nitrogen (RNS) and Sulfur (RSS) species allow organisms to detect and respond to metabolic and environmental stressors, such as exercise and altitude exposure.
Andrew F. Cumpstey, Magdalena Minnion, Bernadette O. Fernandez, Monika Mikus-Lelinska, Kay Mitchell, Daniel S. Martin, Michael P.W. Grocott, Martin Feelisch   +7 more
doaj   +1 more source

Hypothesis : soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease [PDF]

, 2010
Considerable evidence points to oxidative stress in the brain as an important event in the early stages of Alzheimer's disease (AD). The transition metal ions of Cu, Fe, and Zn are all enriched in the amyloid cores of senile plaques in AD.
Tabner, Brian J, Allsop, David, Mayes, Jennifer   +2 more
core   +5 more sources

S-nitrosothiols and H2S donors: Potential chemo-therapeutic agents in cancer

Redox Biology, 2019
Nitric Oxide (NO) and Hydrogen Sulfide (H2S) are components of an “interactome”, which is defined as a redox system involving the interactions of RSS, RNS and ROS.
Adriana Karla Cardoso Amorim Reis, Arnold Stern, Hugo Pequeno Monteiro   +2 more
doaj   +1 more source

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J., Hancock, Robert E W, Foroushani, Amir K, Brinkman, Fiona S L   +37 more
core   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Redox Conformation-Specific Protein–Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis

Antioxidants, 2020
2-Cysteine peroxiredoxins (2-CysPRX) are highly abundant thiol peroxidases in chloroplasts and play key roles in reactive oxygen species (ROS) defense and redox signaling.
Michael Liebthal, Johannes Schuetze, Anna Dreyer, Hans-Peter Mock, Karl-Josef Dietz   +4 more
doaj   +1 more source

RETRASO, a code for modeling reactive transport in saturated and unsaturated porous media [PDF]

, 2004
The code RETRASO (REactive TRAnsport of SOlutes) simulates reactive transport of dissolved and gaseous species in non-isothermal saturated or unsaturated problems.
Saaltink, Maarten, Ayora, Carles, Carrera Ramírez, Jesús, Ayora Ibáñez, Carlos, Olivella Pastallé, Sebastià, Ayora, C., Olivella, Sebastià, Saaltink, Maarten W., Olivella, S., Ayora, Carlos, Batlle, F., Carrera, J., Batlle Pifarré, Francisco, Carrera, Jesús   +13 more
core   +1 more source

The global Microcystis interactome [PDF]

, 2020
Bacteria play key roles in the function and diversity of aquatic systems, but aside from study of specific bloom systems, little is known about the diversity or biogeography of bacteria associated with harmful cyanobacterial blooms (cyanoHABs).
Jiang, H., Meyer, E.I., Hamilton, D.P., Cai, H., Padisák, J., Cook, K.V., Krumholz, L.R, Burford, M.A., Zhu, G., Wilson, A.E., Sukenik, A., Li, C., Latour, D., Paerl, H.W., Grossart, H.-P., Steffen, M.M., Hambright, K.D., Qin, B., Zamor, R.M.   +18 more
core   +1 more source