Results 51 to 60 of about 1,302,618 (294)

Read Length Dominates Phylogenetic Placement Accuracy of Ancient DNA Reads

Molecular Biology and Evolution
AbstractA common problem when analyzing ancient DNA (aDNA) data is to identify the species which corresponds to the recovered aDNA sequence(s). The standard approach is to deploy sequence similarity based tools such as BLAST. However, as aDNA reads may frequently either stem from unsampled taxa due to extinction, it is likely that there is no exact ...
Ben Bettisworth, Nikolaos Psonis, Nikos Poulakakis, Pavlos Pavlidis, Alexandros Stamatakis   +4 more
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Does it matter if some learners read slowly? Exploring relationships between reading comprehension and oral reading fluency

South African Journal of Childhood Education
Background: Although Zimbabwe has performed quite well on Grade 6 SACMEQ literacy assessments compared to other African countries, reading levels are generally low and there is little research on reading literacy in Zimbabwean primary schools.
Fungai Mutema, Elizabeth J. Pretorius
doaj   +1 more source

Reading Self-Concept and Reading Anxiety in Second Grade Children: The Roles of Word Reading, Emergent Literacy Skills, Working Memory and Gender

Frontiers in Psychology, 2018
Background: Most studies in the field of reading have focused on the linguistic and cognitive factors. Less is known about the affective aspects of reading in young readers, such as self-perceptions of reading, and reading anxiety.Aims: This study aimed ...
Tami Katzir, Young-Suk G. Kim, Shahar Dotan   +2 more
doaj   +1 more source

Relationship Between Scholastic and Health Behaviors and Reading Level in Adolescent Females [PDF]

, 2000
This was a study of 102 adolescent females, 12-20 years of age, presenting to a central city clinic for medical care. Participants completed an oral questionnaire that included demographics, and questions regarding scholastic history, sexual behavior ...
Haglund, Kristin, Matson, Steven C.
core   +1 more source

Music-reading expertise modulates the visual span for English letters but not Chinese characters. [PDF]

, 2019
Recent research has suggested that the visual span in stimulus identification can be enlarged through perceptual learning. Since both English and music reading involve left-to-right sequential symbol processing, music-reading experience may enhance ...
Chung, Susana TL, Hsiao, Janet H, Li, Sara TK   +2 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The 4M (Look-Organize-Spell-Read) Intervention to Improve Reading Accuracy in Slow Learners: A Single-Case Study

Gadjah Mada Journal of Professional Psychology
This single-case study aimed to evaluate the effectiveness of the 4M intervention in improving reading accuracy among slow learners with reading challenges.
Isnaini Rakhmi Khoirunnisa Massitoh, Haryanta Haryanta   +1 more
doaj   +1 more source

The relationship between visual memory of non-words and accuracy and rate reading among female first-graders living in Isfahan-Iran

مجله پژوهش در علوم توانبخشی, 2011
Introduction: Reading accuracy depends on such skills as normal hearing, auditory perception, auditory memory, normal visual perception and visual memory. The aim of this study was to determine the relationship between two reading skills, namely accuracy
Nahid Baharlooie, Saghar GHolami, Maede SHariat, Mitra Nikzad   +3 more
doaj   +1 more source