Results 101 to 110 of about 1,940,419 (280)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Implementasi Gerakan Literasi Sekolah dalam Kegiatan Membaca di SDN 1 Pangkalan Banteng Kalimantan Tengah [PDF]
The reading ability of students in Indonesia is still relatively low because there are students who do not recognize letters, lack understanding of reading content, and lack enthusiasm when reading both in low and high grades.
Fanesha, Icha Fina
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Introduction to chaos and diffusion
This contribution is relative to the opening lectures of the ISSAOS 2001 summer school and it has the aim to provide the reader with some concepts and techniques concerning chaotic dynamics and transport processes in fluids.
Boffetta, G., Lacorata, G., Vulpiani, A.
core
Teaching Techniques in Reading Used on Students' Classroom Action Research Papers [PDF]
:This research entitled Teaching Techniques in Reading Used on Students' Classroom Action Research Papers. The purpose of this research is to find out teaching techniques in reading used on students' classroom action research papers and modifications to ...
Anggraini, M. (Maulidya) +2 more
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Applying CLIL Techniques to Teach Analytic Philosophy in English [PDF]
I have been lecturing Analytic Philosophy course in English at Oles Honchar Dnipro National University, Ukraine, for three years. Teaching using CLIL (Content and Language Integrated Learning) techniques enables me to do it effectively.
Kulyk, Oleksandr
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source

