Results 101 to 110 of about 1,934,051 (281)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
PSYCHO-PEDAGOGICAL INTERVENTION STRUCTURED ON COMPONENTS SPECIFIC TO READING AND WRITING ACTIVITIES [PDF]
Studia Universitatis Babeş-Bolyai. Psychologia-Paedagogia, 2012 . This research aims to investigate the efficacy of the psycho- pedagogical intervention program structured on techniques that develop the organizational skills of students with attention deficit hyperactivity disorder who have reading and writing ...
CLAUDIA-DOINA GREC, OLGA CHIŞ
doaj
Воспроизведение этнической концептуальной картины мира в украинском, русском, французском и арабском переводах сказки О.Уальда "Соловей и роза" [PDF]
, 2015 Reading is central to Cognitive Poetics (Stockwell 2002: 1), yet, what about the reading of a translator? Schulte claims: "The translator develops reading techniques that are distinctly different from those of a critic or scholar".
Боучуачі, Суфьян +1 more
core
Are e-readers suitable tools for scholarly work?
, 2012 This paper aims to offer insights into the usability, acceptance and limitations of e-readers with regard to the specific requirements of scholarly text work.
Mayr, Philipp +2 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
IMPROVING STUDENTS’ READING COMPREHENSION THROUGH JIGSAW TECHNIQUE [PDF]
, 2019 Halimah Halimah +2 more
openalex +1 more source
Introduction to chaos and diffusion
, 2003 This contribution is relative to the opening lectures of the ISSAOS 2001 summer school and it has the aim to provide the reader with some concepts and techniques concerning chaotic dynamics and transport processes in fluids.
Boffetta, G., Lacorata, G., Vulpiani, A.
core
Big Book For Student’s Reading Interest to Teach Kinds of Activity [PDF]
, 2017 Reading activities for children are interesting and important activities to remind learning and understanding language. Many techniques and activities have been proposed in the literature theory for reading activities to be fun in the classroom or ...
Mustika, Amelia Winda +2 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source