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Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors.
Immunology, 1995The C5a anaphylatoxin is a potent complement-derived mediator of inflammation with chemotactic activity. In this study the possible role of specific high-affinity binding sites for C5a on peripheral blood leucocytes for the removal of C5a from human blood plasma was investigated.
M, Oppermann, O, Götze
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Journal of Clinical Oncology, 2012
e21084 Background: Accumulated evidence has revealed implications of chemokines and their receptors in the pathophysiology of cancer. Anaphylatoxin C5a, a fragment of the complement 5th component (C5), is a potent chemokine for leukocytes that express the C5a receptor (C5aR).
Hidetoshi Nitta +3 more
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e21084 Background: Accumulated evidence has revealed implications of chemokines and their receptors in the pathophysiology of cancer. Anaphylatoxin C5a, a fragment of the complement 5th component (C5), is a potent chemokine for leukocytes that express the C5a receptor (C5aR).
Hidetoshi Nitta +3 more
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Expression of the complement C5a anaphylatoxin receptor (C5aR) on non-myeloid cells
Immunology Letters, 1995The expression of the complement C5a anaphylatoxin receptor (C5aR) has traditionally been thought to be limited to myeloid blood cells, including neutrophils, monocytes, macrophages, and eosinophils. Immunohistochemistry and ligand-binding studies reported here demonstrate, however, that C5aR is expressed by parenchymal cells of several solid organs ...
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Immunogenetics, 2003
In the course of suppression subtractive hybridization between the cDNA of phytohemagglutinin-stimulated and non-stimulated head kidney cells in rainbow trout (Oncorhynchus mykiss), a cDNA clone was obtained that showed most similarity to mammalian receptor for the anaphylatoxin of the fifth complement component (C5aR).
Kazuhiro, Fujiki +3 more
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In the course of suppression subtractive hybridization between the cDNA of phytohemagglutinin-stimulated and non-stimulated head kidney cells in rainbow trout (Oncorhynchus mykiss), a cDNA clone was obtained that showed most similarity to mammalian receptor for the anaphylatoxin of the fifth complement component (C5aR).
Kazuhiro, Fujiki +3 more
openaire +2 more sources
Complement Regulation in Human Tenocytes under the Influence of Anaphylatoxin C5a
International Journal of Molecular Sciences, 2021Benjamin Kohl, Gundula Schulze-Tanzil
exaly
C5L2, the Second C5a Anaphylatoxin Receptor, Suppresses LPS-Induced Acute Lung Injury
American Journal of Respiratory Cell and Molecular Biology, 2016Ruobing Wang
exaly