Results 21 to 30 of about 271,431 (312)

Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism [PDF]

Hormone and Metabolic Research, 2020
AbstractPrimary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT1R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA.
Meyer L. S., Gong S., Reincke M., Williams T. A.   +3 more
openaire   +5 more sources

Angiotensin II Type 1 Receptor Autoantibodies in Postural Tachycardia Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundBoth the adrenergic and renin‐angiotensin systems contribute to orthostatic circulatory homeostasis, which is impaired in postural orthostatic tachycardia syndrome (POTS).
Xichun Yu, Hongliang Li, Taylor A. Murphy, Zachary Nuss, Jonathan Liles, Campbell Liles, Christopher E. Aston, Satish R. Raj, Artur Fedorowski, David C. Kem   +9 more
doaj   +1 more source

Enhancement of Adipocyte Browning by Angiotensin II Type 1 Receptor Blockade. [PDF]

PLoS ONE, 2016
Browning of white adipose tissue (WAT) has been highlighted as a new possible therapeutic target for obesity, diabetes and lipid metabolic disorders, because WAT browning could increase energy expenditure and reduce adiposity.
Kana Tsukuda, Masaki Mogi, Jun Iwanami, Harumi Kanno, Hirotomo Nakaoka, Xiao-Li Wang, Hui-Yu Bai, Bao-Shuai Shan, Masayoshi Kukida, Akinori Higaki, Toshifumi Yamauchi, Li-Juan Min, Masatsugu Horiuchi   +12 more
doaj   +1 more source

Cytokine Profiles Associated With Angiotensin II Type 1 Receptor Antibodies

Kidney International Reports, 2019
Introduction: Angiotensin II type 1 receptor antibody (AT1R-Ab), is a non–human leukocyte antigen (HLA) antibody implicated in poor renal allograft outcomes, although its actions may be mediated through a different pathway than HLA donor-specific ...
Meghan H. Pearl, Jonathan Grotts, Maura Rossetti, Qiuheng Zhang, David W. Gjertson, Patricia Weng, David Elashoff, Elaine F. Reed, Eileen Tsai Chambers   +8 more
doaj   +1 more source

Type 1 angiotensin II receptors in human endometrium [PDF]

Molecular Human Reproduction, 1996
From evidence based on the use of specific receptor subtype antagonists, it has generally been assumed that human uterine tissue contains only type 2 (AT2) angiotensin II (AII) receptor subtype. Using a monoclonal antibody, 6313/G2, directed against a specific sequence in the extracellular domain of the type 1 AII receptor (AT1), in immunocytochemical ...
E, Saridogan, O, Djahanbakhch, J R, Puddefoot, C, Demetroulis, R, Dawda, A J, Hall, G P, Vinson   +6 more
openaire   +2 more sources

Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade [PDF]

, 2001
ACE inhibitors block B(2) receptor desensitization, thereby potentiating bradykinin beyond blocking its hydrolysis. Angiotensin (Ang)-(1-7) also acts as an ACE inhibitor and, in addition, may stimulate bradykinin release ...
Danser, A.H.J. (Jan), Saxena, P.R. (Pramod Ranjan), Tom, B. (Beril), Vries, R.R.P. (René) de   +3 more
core   +1 more source

ANGIOTENSIN II TYPE 1 RECEPTOR AUTOANTIBODIES

Journal of Hypertension, 2019
Objective:Primary aldosteronism (PA), the most common cause of endocrine hypertension, is a disorder due to bilateral adrenal hyperplasia (BAH) and aldosterone producing adenoma (APA), featuring concentrations of plasma aldosterone that are inappropriately high for the circulating renin levels ...
M. Piazza, T.M. Seccia, B. Caroccia, G. Rossitto, G.P. Rossi   +4 more
openaire   +2 more sources

Angiotensin Type 1 Receptor Blockers in Heart Failure

Current Drug Targets, 2020
Homeostasis in the cardiovascular system is maintained by physiological functions of the Renin Angiotensin Aldosterone System (RAAS). In pathophysiological conditions, over activation of RAAS leads to an increase in the concentration of Angiotensin II (AngII) and over activation of Angiotensin Type 1 Receptor (AT1R), resulting in vasoconstriction ...
Khuraijam Dhanachandra, Singh, Sadashiva S, Karnik   +1 more
openaire   +3 more sources

Hypertension: Renin-Angiotensin-Aldosterone System Alterations [PDF]

, 2015
Blockers of the renin-angiotensin-aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the ...
Danser, A.H.J. (Jan), Esch, J.H.M. (Joep) van, Meiracker, A.H. (Anton) van den, Riet, L. (Luuk) te, Roks, A.J.M. (Anton)   +4 more
core   +1 more source

The potential therapeutic use of renin-angiotensin system inhibitors in the treatment of inflammatory diseases [PDF]

, 2019
Inflammation is a normal part of the immune response to injury or infection but its dysregulation promotes the development of inflammatory diseases, which cause considerable human suffering.
Avan, Amir, Ferns, Gordon A, Ghasemi, Faezeh, Hesari, AmirReza, Ranjbar, Reza, Shafiee, Mojtaba   +5 more
core   +1 more source