AbstractThe receptor subtype mediating the bradykinin (Bk)-induced burst of prostaglandin formation in osteoblasts has been studied. Bk, but not des-Arg9-Bk, induced the formation of prostaglandin E2 and prostacyclin in neonatal mouse calvarial bones incubated for 30 minutes.
O, Ljunggren +3 more
openaire +2 more sources
Neurochemical mechanism of muscular pain: Insight from the study on delayed onset muscle soreness
We reviewed fundamental studies on muscular pain, encompassing the characteristics of primary afferent fibers and neurons, spinal and thalamic projections, several muscular pain models, and possible neurochemical mechanisms of muscle pain.
Kazue Mizumura, Toru Taguchi
doaj +1 more source
Plasma extravasation mediated by lipopolysaccharide-induction of kinin B1 receptors in rat tissues
The present study was performed to: (a) evaluate the effects of kinin B1 (Sar{D-Phe8}-des-Arg9-BK; 10 nmol/kg) and B2 (bradykinin (BK); 10 nmol/kg) receptor agonists on plasma extravasation in selected rat tissues; (b) determine the contribution of a ...
Paulo Roberto Wille +3 more
doaj +1 more source
Background: Bradykinin is an endogenously produced nonapeptide with many physiological and pathological functions that are mediated by two pharmacologically defined receptor subtypes, B1- and B2-receptors.
Najam A. Sharif +4 more
doaj +1 more source
Hereditary angioedema: epidemiology, management, and role of icatibant
Aasia Ghazi, J Andrew GrantUniversity of Texas Medical Branch, Division of Allergy and Clinical Immunology, Galveston, TX, USAAbstract: Hereditary angioedema (HAE) is an autosomal dominant, potentially life-threatening condition, manifesting as recurrent
Ghazi A, Grant JA
doaj
Renin-angiotensin and kallikrein-kinin systems in diabetic retinopathy [PDF]
This brief review describes how two complex systems, the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), affect the retina.
Igić Rajko
doaj
Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes. [PDF]
Riedl MA +11 more
europepmc +1 more source
Tumor-Selective Vascular Modulation by Acid-Cleavable Retro-Inverso Bradykinin Conjugates Enhances the Antitumor Efficacy of Nanomedicine. [PDF]
Assumang A +6 more
europepmc +1 more source
Pharmacological Characterization of Vasomotor Responses in the Tree Shrew (<i>Tupaia belangeri</i>) Basilar Artery: A Promising Model for Human Cerebrovascular Research. [PDF]
Islam MZ +4 more
europepmc +1 more source

