Results 21 to 30 of about 43,721 (231)
The Impact of CB1 Receptor on Inflammation in Skeletal Muscle Cells
Journal of Inflammation Research, 2021 Mansour Haddad Faculty of Pharmacy, Philadelphia University, Amman, JordanCorrespondence: Mansour Haddad Email Dr.man.haddad@gmail.comBackground: Various factors trigger the inflammatory response and cytokine activation in skeletal muscle.
Haddad M
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Cannabinoid receptor type-1: breaking the dogmas [version 1; referees: 3 approved]
F1000Research, 2016 The endocannabinoid system (ECS) is abundantly expressed in the brain. This system regulates a plethora of physiological functions and is composed of cannabinoid receptors, their endogenous ligands (endocannabinoids), and the enzymes involved in the ...
Arnau Busquets Garcia +3 more
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Impaired Excitatory Neurotransmission in the Urinary Bladder from the Obese Zucker Rat: Role of Cannabinoid Receptors. [PDF]
PLoS ONE, 2016 Metabolic syndrome (MS) is a known risk factor for lower urinary tract symptoms. This study investigates whether functional and expression changes of cannabinoid CB1 and CB2 receptors are involved in the bladder dysfunction in an obese rat model with ...
Igor Blaha +10 more
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Crystal structures of agonist-bound human cannabinoid receptor CB1
Nature, 2017 The cannabinoid receptor 1 (CB1) is the principal target of the psychoactive constituent of marijuana, the partial agonist Δ9-tetrahydrocannabinol (Δ9-THC).
T. Hua +18 more
semanticscholar +1 more source
Neurobiology of Disease, 2005 We have observed that systemic administration of cannabinoid CB1 antagonists exerts antiparkinsonian effects in rats with very severe nigral lesion (>95% cell loss), but not in rats with less severe lesion (85–95% cell loss).
Emilio Fernandez-Espejo +6 more
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Neuropharmacology, 2017 Cannabinoid pharmacology has been intensely studied because of cannabis’ pervasive medicinal and non-medicinal uses as well as for the therapeutic potential of cannabinoid-based drugs for the treatment of pain, anxiety, substance abuse, obesity, cancer ...
Leepakshi Khurana +3 more
semanticscholar +1 more source
Expression of the endocannabinoid receptors in human fascial tissue
European Journal of Histochemistry, 2016 Cannabinoid receptors have been localized in the central and peripheral nervous system as well as on cells of the immune system, but recent studies on animal tissue gave evidence for the presence of cannabinoid receptors in different types of tissues ...
C. Fede +6 more
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2-AG and anandamide enhance hippocampal long-term potentiation via suppression of inhibition
Frontiers in Cellular Neuroscience, 2022 It is widely accepted that exogenous cannabinoids can impair short-term memory and cognition in humans and other animals. This is likely related to the inhibition of long-term potentiation (LTP), a form of synaptic plasticity, by the global and sustained
Fouad Lemtiri-Chlieh, Eric S. Levine
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Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor
Medicinal research reviews (Print), 2016 The cannabinoid CB1 receptor is a G protein coupled receptor and plays an important role in many biological processes and physiological functions. A variety of CB1 receptor agonists and antagonists, including endocannabinoids, phytocannabinoids, and ...
Thuy-Ai T Nguyen +5 more
semanticscholar +1 more source
Cells, 2023 Cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2) are components in the endocannabinoid system that play significant roles in regulating immune responses. There are many agonists for the cannabinoid receptors; however, their effects on T cell
Nuchjira Takheaw +4 more
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