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Insulin Receptor and Insulin Action
1990Insulin generates a complex assay of biological responses in a variety of cell systems. The first step in insulin action is binding of the hormone to its specific cell surface receptor. This receptor is an oligomer consisting of two α-subunits with Mr 130 kDa, and twos-subunits with Mr 95 kDa; the different subunits are linked together by disulfide ...
E. Obberghen, R. Ballotti
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Evolution of Insulin and Insulin Receptors
1987Insulin traditionally has been considered to be a unique product of the vertebrate pancreas. More recent studies, however, have suggested that there may be extrapancreatic sources of insulin and that insulin may act on tissues other than its classic target tissues.
Derek LeRoith +2 more
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The aetiology and molecular landscape of insulin resistance
Nature Reviews Molecular Cell Biology, 2021David E James +2 more
exaly
Insulin receptors and insulin signalling
1995International ...
Taouis, Mohammed, Simon, J.
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The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia
Cell Metabolism, 2021Lykke Sylow +2 more
exaly