Results 91 to 100 of about 6,476 (207)

Rat pial microvascular responses to melatonin during bilateral common carotid artery occlusion and reperfusion [PDF]

open access: yes, 2011
The present study assessed the in vivo rat pial microvascular responses induced by melatonin during brain hypoperfusion and reperfusion (RE) injury. Pial microcirculation of male Wistar rats was visualized by fluorescence microscopy through a closed ...
Cardaci E   +4 more
core   +1 more source

Correlation between sleep problems and morning serum melatonin and ferritin levels in Japanese 5‐year‐old children with autism spectrum disorder

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Aim Children with autism spectrum disorder (ASD) are more likely to have sleep problems. Few studies have investigated the relationship between sleep problems and blood melatonin and ferritin levels. The objective of this study was to determine the correlation between sleep problems and morning serum melatonin and ferritin levels, and the ...
Ai Terui   +7 more
wiley   +1 more source

Differential Function of Melatonin MT1 and MT2 Receptors in REM and NREM Sleep

open access: yesFrontiers in Endocrinology, 2019
The pathophysiological function of the G-protein coupled melatonin MT1 and MT2 receptors has not yet been well-clarified. Recent advancements using selective MT1/ MT2 receptor ligands and MT1/MT2 receptor knockout mice have suggested that the activation ...
Gabriella Gobbi   +2 more
doaj   +1 more source

Molecular mechanisms of the sleep wake cycle : therapeutic applications to insomnia [PDF]

open access: yes, 2017
The aim of this review is to explore the molecular mechanism and genetic components of the sleepwake cycle and insomnia. Moreover, we wanted to review the correlation between primary insomnia and its comorbidities.
Grima, Melanie   +2 more
core   +1 more source

Sleep quality and sleepiness in adults with multiple myeloma. Is melatonin a potential treatment?

open access: yesPhysiological Reports, Volume 14, Issue 5, March 2026.
Abstract Sleep disturbances significantly impact quality of life in cancer patients, yet remain poorly characterized in multiple myeloma (MM). This observational study aimed to characterize sleep profiles in MM patients and evaluate the therapeutic potential of exogenous melatonin.
Mariana Fiori   +5 more
wiley   +1 more source

Ultrastructural evidence of a secretory role for melatonin in the human parotid gland [PDF]

open access: yes, 2015
In vivo animal studies show that pentagastrin, cholecystokinin and melatonin cause the secretion and synthesis of salivary proteins. Melatonin occurs in large amounts in the gut and is released into the blood on food intake.
Ekstrom, J.   +6 more
core  

Findings on Impact of Circadian Genes and Bipolar Disorder: A Bibliometric Analysis From 1996 to 2024

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
This study maps global research trends on circadian genes and bipolar disorder from 1996 to 2024 using bibliometric methods. Analysis of 400 articles reveals a steady growth in publications, with the USA, Italy, and China as leading contributors. Key research hotspots include depression, neuronal mechanisms, light therapy, genetic associations, and ...
Zhuoer Ruan, Jie Zhu
wiley   +1 more source

Comparison of The Melatonin Preconditioning Efficacy between Bone Marrow and Adipose-Derived Mesenchymal Stem Cells [PDF]

open access: yes, 2017
Objective: Mesenchymal stem cells (MSC) from various sources have the potentials to positively affect regenerative medicine. Furthermore, pre-conditioning strategies with different agents could improve the efficacy of cell therapy.
Alizadeh, Akram   +4 more
core   +1 more source

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

open access: yesCell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar   +5 more
wiley   +1 more source

MT1 melatonin receptor mRNA tissular localization by PCR amplification.

open access: yesNeuro endocrinology letters, 2003
The pineal gland transduces photoperiodic informations to the neuroendocrine axis through the nocturnally melatonin secretion. This hormonal message plays a major role in the biological rhythm regulation. By autoradiography, more than 130 melatonin putative targets have been reported in the central nervous system (CNS) and in peripheral tissues ...
Poirel, Vincent Joseph   +5 more
openaire   +2 more sources

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