Results 81 to 90 of about 6,339 (219)
Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
, 2019 Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
Autoantibodies against muscarinic receptors in breast cancer. Its role in tumor angiogenesis. [PDF]
, 2013 The presence of autoantibodies in cancer has become relevant in recent years. We demonstrated that autoantibodies purified from the sera of breast cancer patients activate muscarinic acetylcholine receptors in tumor cells.
Azar, María Eugenia +7 more
core +1 more source
Regulation of Src Family Tyrosine Kinases in the Rat Striatum by Muscarinic Acetylcholine Receptors [PDF]
, 2017 Acetylcholine is an important neurotransmitter in the mammalian brain. This transmitter binds to muscarinic acetylcholine receptors (mAChR) to regulate activity of a variety of intracellular signaling molecules.
Faris, Hunter
core
Long-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats. [PDF]
, 2016 Estradiol (E2) robustly activates transcription of a broad array of genes in the hippocampal formation of middle-aged ovariectomized rats via estrogen receptors (ERalpha, ERbeta, and G protein-coupled ER).
Hrabovszky, E. +5 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
Cancer Reports, Volume 8, Issue 11, November 2025.ABSTRACT Background The prevalence of cancer poses significant challenges to treatment, largely because of drug resistance along with other side effects. Current studies have been investigating the growth factors more than other biologic tumor features, such as neurobiologic features.
Mohammad Hossein Azadi +3 more
wiley +1 more source
Autoantibodies against M5-muscarinic and beta1-adrenergic receptors in periodontitis patients
Aging, 2020 Autoantibodies against muscarinic and beta1-adrenergic receptors are considered a potential cause and/or risk factor for chronic heart failure. Association of periodontitis with such autoantibodies and with impaired heart function has been observed in patients exposed to endemic Chagas' disease, which triggers by itself cardiomyopathy and receptor ...
Scherbaum, Isabel +5 more
openaire +2 more sources
Molecular OncologyMicrotubule‐targeting agents represent one of the most successful classes of anticancer agents. However, the development of drug resistance and the appearance of adverse effects hamper their clinical implementation.
Yao‐Yu Hsieh +2 more
doaj +1 more source
Frontiers in Molecular NeuroscienceFive muscarinic acetylcholine (mACh) receptor subtypes are divided into two classes: the M1 class (M1, M3, and M5) and the M2 class (M2 and M4). The former is coupled to Gq proteins, while the latter is coupled to Gi/o proteins.
Li-Min Mao +4 more
doaj +1 more source
Accumbal Cholinergic Interneurons Differentially Influence Motivation Related to Satiety Signaling [PDF]
, 2017 Satiety, rather than all or none, can instead be viewed as a cumulative decrease in the drive to eat that develops over the course of a meal. The nucleus accumbens (NAc) is known to play a critical role in this type of value reappraisal, but the ...
Aitta-aho, Teemu Heikki Juhani +8 more
core +2 more sources