Results 111 to 120 of about 22,802 (228)

Focal Spot, Fall/Winter 2001 [PDF]

, 2001
https://digitalcommons.wustl.edu/focal_spot_archives/1089/thumbnail ...

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5-HT2A receptor is the predominant receptor mediating contraction of the isolated porcine distal ureter to 5-HT in young and old animals [PDF]

, 2018
Isolated ureteral strips develop spontaneous phasic contractile activity which is enhanced by 5-hydroytryptamine (5-HT). The aim of this study was to identify the receptor subtype mediating these responses and to determine whether responses to 5-HT ...
Chess-Williams, Russ, Lim, Iris, Sellers, Donna   +2 more
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[Genetic dysfunction of the serotonin receptor 5-HT2A in psychiatric disorders].

Actas espanolas de psiquiatria, 2001
So far, there is increasing evidence of the active role of molecular biology in the psychiatric nosology as well as in the identification of psychiatric fenotypes. In this respect, the neurotransmitter serotonin (5-HT) has been involved in the etiopathogeny of multiple psychiatry conditions, such as affective disorder, schizophrenia, panic disorder ...
Arranz, B., Rosel, P., Ramírez, N., San, L.   +3 more
openaire   +3 more sources

Limited Associations Between 5-HT Receptor Gene Polymorphisms and Treatment Response in Antidepressant Treatment-Free Patients With Depression

Frontiers in Pharmacology, 2019
Major depressive disorder has become a prominent cause of disability, as lifetime prevalence has increased to ~15% in the Western world. Pharmacological effects of serotonin (5-hydroxytryptamine, 5-HT) are mediated through 5-hydroxytryptamine receptor (5-
Taichi Ochi, Natalya M. Vyalova, Innokentiy S. Losenkov, Diana Z. Paderina, Diana Z. Paderina, Ivan V. Pozhidaev, Ivan V. Pozhidaev, Anton J. M. Loonen, Anton J. M. Loonen, German G. Simutkin, Nikolay A. Bokhan, Nikolay A. Bokhan, Nikolay A. Bokhan, Svetlana A. Ivanova, Svetlana A. Ivanova, Svetlana A. Ivanova, Bob Wilffert, Bob Wilffert   +17 more
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Neuroreceptor imaging in depression

Neurobiology of Disease, 2013
The in vivo study of receptor binding potential in the human brain is made possible by positron emission tomography (PET) imaging. Here we review PET studies of neuroreceptor function in mood disorders — specifically, major depressive disorder (MDD) and ...
Jonathan B. Savitz, Wayne C. Drevets
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Pinpointing brainstem mechanisms responsible for autonomic dysfunction in Rett syndrome:therapeutic perspectives for 5-HT1A agonists [PDF]

, 2014
Rett syndrome is a neurological disorder caused by loss of function of methyl-CpG-binding protein 2 (MeCP2). Reduced function of this ubiquitous transcriptional regulator has a devastating effect on the central nervous system.
Abdala, Ana Paula, Bissonnette, John, Newman-Tancredi, Adrian   +2 more
core   +3 more sources

Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors

Journal of Molecular and Cellular Cardiology, 2009
Platelet activation occurs in different acute and chronic heart diseases including myocardial infarction, obstructive hypertrophic cardiomyopathy and valve stenosis. Recent studies suggested that some factors secreted by activated platelets may participate in cardiac remodeling.
Yabanoglu, Samiye, Akkiki, Mansour, Seguelas, Marie-Helène, Mialet-Perez, Jeanne, Parini, Angelo, Pizzinat, Nathalie   +5 more
openaire   +3 more sources

Serotonin 5-HT2A and 5-HT2C receptors differentially modulate the acquisition and expression of voluntary alcohol drinking in male mice

Frontiers in Neuroscience
IntroductionStudies suggest that serotonin (5-HT) plays an important role in alcohol use disorder (AUD). While several receptor subtypes modulate the role of 5-HT in AUD, evidence suggests that 5-HT2A and 5-HT2C receptors may be directly involved in ...
Sandy C. Simões, Livia N. Amorim, Yasmim A. Serra, Camila S. Abreu, Maria Clara E. Santana, João P. C. Leite, Carla M. Kaneto, Roberta C. A. Costa, Kaio R. Ferreira, Isabelle C. S. de Oliveira, Alexandre J. Oliveira-Lima, Agnieszka Sulima, Kenner C. Rice, Eduardo A. V. Marinho, Lais F. Berro, Lais F. Berro   +15 more
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Serotonergic Polymorphisms and Psychotic Disorders in Populations From North Spain [PDF]

, 2004
There is strong biological evidence relating alterations in the serotonergic system with mental disorders. These alterations may be originated at the DNA level by sequence mutations that alter the functioning of serotonin receptors and
Arranz, M.J. (M. J.), Beperet, M. (M.), Clark, D. (D.), Kerwin, R.W. (R. W.), Lai, T. (T.), Mata, I. (I.), Ortuño-Sanchez-Pedreño, F. (Felipe), Patiño-García, A. (Ana), Perez-Nievas, F. (F.), Richards, S. (S.), Sham, P. (P.), Sierrasesumaga, L. (Luis)   +11 more
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5-HT2A Serotonin Receptor Density in Adult Male Rats’ Hippocampus after Morphine-based Conditioned Place Preference

Basic and Clinical Neuroscience, 2016
Introduction: A close interaction exists between the brain opioid and serotonin (5-HT) neurotransmitter systems. Brain neurotransmitter 5-HT plays an important role in the regulation of reward-related processing.
Rabie Mohammadi, Mehrdad Jahanshahi, Seyed Behnamedin Jameie   +2 more
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