Results 21 to 30 of about 63,264 (143)

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

BMC Musculoskeletal Disorders, 2019
Background The expression of the receptor activator of nuclear factor kappa B (RANK) /RANK ligand (RANKL) /osteoprotegerin (OPG) system and its association with the progression of intervertebral disc (IVD) degeneration has recently been reported in a ...
Tomohiko Sano, Koji Akeda, Junichi Yamada, Norihiko Takegami, Takao Sudo, Akihiro Sudo   +5 more
doaj   +1 more source

The Skeletal-Protecting Action and Mechanisms of Action for Mood-Stabilizing Drug Lithium Chloride: Current Evidence and Future Potential Research Areas

Frontiers in Pharmacology, 2020
Lithium, the lightest natural-occurring alkali metal with an atomic number of three, stabilizes the mood to prevent episodes of acute manic and depression.
Sok Kuan Wong, Kok-Yong Chin, Kok-Yong Chin, Soelaiman Ima-Nirwana   +3 more
doaj   +1 more source

Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

Frontiers in Pharmacology, 2022
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from plants. In this review, the advances in bioactive alkaloids with respect to their chemical structures, herbal sources, and effects for the prevention and treatment ...
Bingfeng Lin, Pingcui Xu, Juan Zheng, Xuehui Deng, Qitao Ye, Zhongping Huang, Nani Wang   +6 more
doaj   +1 more source

Potensi gel Stichopus hermanii dan Hyperbaric Oxygen Therapy untuk mempercepat perawatan ortodonti

Potential of Stichopus hermanii gel and Hyperbaric Oxygen Therapy in accelerating orthodontic treatment

Jurnal Kedokteran Gigi Universitas Padjadjaran, 2017
Pendahuluan: Perawatan ortodonti memerlukan inovasi untuk mempercepat waktu perawatan. Perawatan ortodonti menyebabkan adanya daerah tekanan dan tarikan yang dipengaruhi oleh ekspresi Receptor Activator of Nuclear Factor Kappa-b (RANK) pada daerah ...
I Ketut Ika Sandana, Jessica Velisia, Alexander Yunior, Arya Brahmanta, Noengki Prameswari   +4 more
doaj   +1 more source

The Relationship between Serum and Gene Expression Levels of RANK, RANKL and Osteoprotegerin Inflammatory Pathway with Unstable Angina: A Case-control Study

Iranian Journal of Allergy, Asthma and Immunology, 2021
Osteoprotegerin (OPG), receptor activator of nuclear factor-kappa B (RANK) and receptor activator of nuclear factor-kappa B ligand (RANKL), the members of the tumor necrosis factor (TNF) family, have multiple effects on bone metabolism, endocrine ...
Alireza Farrokhian, Mahtab Miraftab, Minoo Chenari, Hossein Akbari, Hassan Nikoueinejad, Effat Naimi   +5 more
doaj   +1 more source

The Role of Osteoprotegerin as a Cardioprotective Versus Reactive Inflammatory Marker: the Chicken or the Egg Paradox

Balkan Medical Journal, 2018
Cardiovascular disease is one of the most frequent causes of mortality and morbidity worldwide. Several variables have been identified as risk factors for cardiovascular disease.
Flora Özkalaycı, Öykü Gülmez, Betül Uğur-Altun, Seithikurippu Ratnas Pandi-Perumal, Armağan Altun   +4 more
doaj   +1 more source

Human osteosarcoma cells express functional receptor activator of nuclear factor‐kappa B

The Journal of Pathology, 2007
AbstractRANK, RANK ligand (RANKL) and osteoprotegerin (OPG) are the key regulators of bone metabolism, both in normal and pathological conditions. Previous data have demonstrated that human osteosarcoma biopsies express RANKL as well as OPG, and functional RANK is expressed in a murine osteosarcoma cell line.
Mori, K., Le Goff, B., Berreur, M., Riet, A., Moreau, A., Blanchard, F., Chevalier, C., Guisle-Marsollier, I., Leger, J., Guicheux, J., Masson, M., Gouin, F., Redini, F., Heymann, D.   +13 more
openaire   +3 more sources

RANK/RANKL/OPG system in the intervertebral disc

Arthritis Research & Therapy, 2017
Background The receptor activator of NF-κB ligand (RANKL), a member of the TNF ligand superfamily, is known to regulate bone metabolism. The expression of each component of the RANK/RANKL/osteoprotegerin (OPG) system in the intervertebral disc (IVD) has ...
Norihiko Takegami, Koji Akeda, Junichi Yamada, Tomohiko Sano, Koichiro Murata, Jenny Huang, Koichi Masuda, Akihiro Sudo   +7 more
doaj   +1 more source

Dieckol isolated from Eisenia bicyclis extract suppresses RANKL-induced osteoclastogenesis in murine RAW 264.7 cells

Asian Pacific Journal of Tropical Biomedicine, 2022
Objective: To demonstrate the effect of dieckol from Eisenia bicyclis on osteoclastogenesis using RAW 264.7 cells. Methods: Murine macrophage RAW 264.7 cells were subjected to dieckol treatment, followed by treatment with receptor activator of nuclear ...
Su-Hyeon Cho, Tae-Hyung Kwon, Hoibin Jeong, Jin Sook Kim, Song-Rae Kim, Myeong Seon Jeong, SeonJu Park, Miri Choi, Jung-Hee Woo, Juhee Ahn, Kil-Nam Kim   +10 more
doaj   +1 more source

The role of skeletal tissue remodeling markers in the patho-genesis of implant-associated inflammation after primary knee arthroplasty [PDF]

Саратовский научно-медицинский журнал, 2018
Aim: to reveal certain mechanisms of the pathogenesis of implant-associated inflammation by the level of resorption and bone tissue genesis markers in patients who underwent primary knee arthroplasty. Material and Methods.
Galashina Е.А., Bondarenko A.S., Ulyanov V.Yu., Klimov S.S.   +3 more
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