Results 21 to 30 of about 112,514 (282)

Osteoprotegerin and Soluble Receptor Activator of Nuclear Factor-Kappa B Ligand in Exudative Age-Related Macular Degeneration

Acta Medica Iranica, 2014
Calcification and inflammation are among the important cases of exudative age-related macular degeneration (E-ARMD). The aim of the present study was to elucidate if there is any relationship between serum Osteoprotegerin (OPG), soluble receptor ...
Amir Ghorbanihaghjo, Alireza Javadzadeh, Nadereh Rashtchizadeh, Rana Sorkhabi, Hasan Khalili, Babak Rahimi-Ardabili   +5 more
doaj   +2 more sources

Dramatic response of aneurysmal bone cyst to denosumab: Case report and literature review

Clinical Case Reports, 2021
Denosumab, a monoclonal antibody that specifically targets cytokine receptor activator of nuclear factor‐kappa B ligand (RANKL), is a potentially viable option in resistant aneurysmal bone cysts.
Pedram Fadavi, Amir Mohammad Arefpour, Ramyar Hariri, Maryam Vasheghani, Maryam Garousi, Farzad Taghizadeh‐Hesary   +5 more
doaj   +1 more source

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

BMC Musculoskeletal Disorders, 2019
Background The expression of the receptor activator of nuclear factor kappa B (RANK) /RANK ligand (RANKL) /osteoprotegerin (OPG) system and its association with the progression of intervertebral disc (IVD) degeneration has recently been reported in a ...
Tomohiko Sano, Koji Akeda, Junichi Yamada, Norihiko Takegami, Takao Sudo, Akihiro Sudo   +5 more
doaj   +1 more source

The Skeletal-Protecting Action and Mechanisms of Action for Mood-Stabilizing Drug Lithium Chloride: Current Evidence and Future Potential Research Areas

Frontiers in Pharmacology, 2020
Lithium, the lightest natural-occurring alkali metal with an atomic number of three, stabilizes the mood to prevent episodes of acute manic and depression.
Sok Kuan Wong, Kok-Yong Chin, Kok-Yong Chin, Soelaiman Ima-Nirwana   +3 more
doaj   +1 more source

Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

Frontiers in Pharmacology, 2022
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from plants. In this review, the advances in bioactive alkaloids with respect to their chemical structures, herbal sources, and effects for the prevention and treatment ...
Bingfeng Lin, Pingcui Xu, Juan Zheng, Xuehui Deng, Qitao Ye, Zhongping Huang, Nani Wang   +6 more
doaj   +1 more source

Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption [PDF]

, 2019
Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs)
Cha, Young-Nam, Dinauer, Mary C., Jang, Jin Sun, Kang, In Soon, Kim, Chaekyun, Kim, Young-June, Lee, Zang Hee   +6 more
core   +2 more sources

Effects of RANKL-Targeted Therapy in Immunity and Cancer. [PDF]

, 2014
The role of the receptor activator of nuclear factor-κB ligand (RANKL)/RANK system is well characterized within bone, where RANKL/RANK signaling mediates osteoclastogenesis and bone resorption.
Cheng, Michael L, Fong, Lawrence
core   +2 more sources

Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease [PDF]

, 2014
Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM ...
Blum B, Eriksen EF, Klein B, Lipton A, Mundy GR, Schmitt CP, Shay G   +6 more
core   +1 more source

Potensi gel Stichopus hermanii dan Hyperbaric Oxygen Therapy untuk mempercepat perawatan ortodonti

Potential of Stichopus hermanii gel and Hyperbaric Oxygen Therapy in accelerating orthodontic treatment

Jurnal Kedokteran Gigi Universitas Padjadjaran, 2017
Pendahuluan: Perawatan ortodonti memerlukan inovasi untuk mempercepat waktu perawatan. Perawatan ortodonti menyebabkan adanya daerah tekanan dan tarikan yang dipengaruhi oleh ekspresi Receptor Activator of Nuclear Factor Kappa-b (RANK) pada daerah ...
I Ketut Ika Sandana, Jessica Velisia, Alexander Yunior, Arya Brahmanta, Noengki Prameswari   +4 more
doaj   +1 more source

The Relationship between Serum and Gene Expression Levels of RANK, RANKL and Osteoprotegerin Inflammatory Pathway with Unstable Angina: A Case-control Study

Iranian Journal of Allergy, Asthma and Immunology, 2021
Osteoprotegerin (OPG), receptor activator of nuclear factor-kappa B (RANK) and receptor activator of nuclear factor-kappa B ligand (RANKL), the members of the tumor necrosis factor (TNF) family, have multiple effects on bone metabolism, endocrine ...
Alireza Farrokhian, Mahtab Miraftab, Minoo Chenari, Hossein Akbari, Hassan Nikoueinejad, Effat Naimi   +5 more
doaj   +1 more source