Results 21 to 30 of about 169,031,329 (267)

Receptor Activator of Nuclear Factor-κB Ligand Activates Nuclear Factor-κB in Osteoclast Precursors* [PDF]

Endocrinology, 2001
Receptor activator of nuclear factor-kappa B ligand [RANK ligand (RANK-L)] stimulates mature osteoclasts to resorb bone, a process associated with NF-kappa B activation. RANK-L also prompts macrophages to develop the osteoclast phenotype. Although NF-kappa B is essential for osteoclast differentiation, it is not known whether RANK-L activates this ...
S, Wei, S L, Teitelbaum, M W, Wang, F P, Ross   +3 more
openaire   +2 more sources

Dramatic response of aneurysmal bone cyst to denosumab: Case report and literature review

Clinical Case Reports, 2021
Denosumab, a monoclonal antibody that specifically targets cytokine receptor activator of nuclear factor‐kappa B ligand (RANKL), is a potentially viable option in resistant aneurysmal bone cysts.
Pedram Fadavi, Amir Mohammad Arefpour, Ramyar Hariri, Maryam Vasheghani, Maryam Garousi, Farzad Taghizadeh‐Hesary   +5 more
doaj   +1 more source

Interactions of porphyromonas gingivalis with bone marrow cells: implications on mediators of bone resorption [PDF]

, 2012
PhDPeriodontitis is a multi-factorial disease characterised by the loss of connective tissue and underlying alveolar bone leading to the loss of teeth. Porphyromonas gingivalis (P.
Reddi, Durga
core   +4 more sources

Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration

BMC Musculoskeletal Disorders, 2019
Background The expression of the receptor activator of nuclear factor kappa B (RANK) /RANK ligand (RANKL) /osteoprotegerin (OPG) system and its association with the progression of intervertebral disc (IVD) degeneration has recently been reported in a ...
Tomohiko Sano, Koji Akeda, Junichi Yamada, Norihiko Takegami, Takao Sudo, Akihiro Sudo   +5 more
doaj   +1 more source

The Skeletal-Protecting Action and Mechanisms of Action for Mood-Stabilizing Drug Lithium Chloride: Current Evidence and Future Potential Research Areas

Frontiers in Pharmacology, 2020
Lithium, the lightest natural-occurring alkali metal with an atomic number of three, stabilizes the mood to prevent episodes of acute manic and depression.
Sok Kuan Wong, Kok-Yong Chin, Kok-Yong Chin, Soelaiman Ima-Nirwana   +3 more
doaj   +1 more source

Receptor activator of nuclear factor kappa B (RANK) expression in primary breast cancer correlates with recurrence-free survival and development of bone metastases in I-SPY1 (CALGB 150007/150012; ACRIN 6657) [PDF]

Breast Cancer Research and Treatment, 2017
Hope Rugo, Christina Yau
exaly   +2 more sources

Effects and mechanisms of natural alkaloids for prevention and treatment of osteoporosis

Frontiers in Pharmacology, 2022
Natural alkaloids are polycyclic, nitrogen-containing, and basic compounds obtained from plants. In this review, the advances in bioactive alkaloids with respect to their chemical structures, herbal sources, and effects for the prevention and treatment ...
Bingfeng Lin, Pingcui Xu, Juan Zheng, Xuehui Deng, Qitao Ye, Zhongping Huang, Nani Wang   +6 more
doaj   +1 more source

Nuclear Factor Kappa B Pathway and human cancer therapeutics [PDF]

, 2009
A thesis submitted in partial fufilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyCancer is one of the major causes of morbidity in the world.
Guo, Xiaoxia
core   +3 more sources

The Relationship between Serum and Gene Expression Levels of RANK, RANKL and Osteoprotegerin Inflammatory Pathway with Unstable Angina: A Case-control Study

Iranian Journal of Allergy, Asthma and Immunology, 2021
Osteoprotegerin (OPG), receptor activator of nuclear factor-kappa B (RANK) and receptor activator of nuclear factor-kappa B ligand (RANKL), the members of the tumor necrosis factor (TNF) family, have multiple effects on bone metabolism, endocrine ...
Alireza Farrokhian, Mahtab Miraftab, Minoo Chenari, Hossein Akbari, Hassan Nikoueinejad, Effat Naimi   +5 more
doaj   +1 more source

Potensi gel Stichopus hermanii dan Hyperbaric Oxygen Therapy untuk mempercepat perawatan ortodonti

Potential of Stichopus hermanii gel and Hyperbaric Oxygen Therapy in accelerating orthodontic treatment

Jurnal Kedokteran Gigi Universitas Padjadjaran, 2017
Pendahuluan: Perawatan ortodonti memerlukan inovasi untuk mempercepat waktu perawatan. Perawatan ortodonti menyebabkan adanya daerah tekanan dan tarikan yang dipengaruhi oleh ekspresi Receptor Activator of Nuclear Factor Kappa-b (RANK) pada daerah ...
I Ketut Ika Sandana, Jessica Velisia, Alexander Yunior, Arya Brahmanta, Noengki Prameswari   +4 more
doaj   +1 more source