Results 61 to 70 of about 78,662 (379)

Polymorphisms of the receptor for advanced glycation end products and glyoxalase I and long-term outcome in patients with breast cancer

Tumor Biology, 2017
Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer.
Petra Tesarova, Tomas Zima, Ales A Kubena, Marta Kalousova   +3 more
doaj   +1 more source

RAGE is a critical factor of sex-based differences in age-induced kidney damage

Frontiers in Physiology, 2023
Introduction: Advanced glycation end products (AGEs) are a heterogeneous group of molecules with potential pathophysiological effects on the kidneys.
Seerat Bajwa, Alexander Luebbe, Ngoc Dong Nhi Vo, Eva-Maria Piskor, Christian Kosan, Gunter Wolf, Ivonne Loeffler   +6 more
doaj   +1 more source

High Mobility Group Box‐1 Drives Fibrosis Progression Signaling via the Receptor for Advanced Glycation End Products in Mice

Hepatology, 2018
High‐mobility group box‐1 (HMGB1) is a damage‐associated molecular pattern (DAMP) increased in response to liver injury. Because HMGB1 is a ligand for the receptor for advanced glycation endproducts (RAGE), we hypothesized that induction of HMGB1 could ...
X. Ge, Elena Arriazu, F. Magdaleno, D. Antoine, Rouchelle D. dela Cruz, N. Theise, N. Nieto   +6 more
semanticscholar   +1 more source

Receptor Mediated Effects of Advanced Glycation End Products (AGEs) on Innate and Adaptative Immunity: Relevance for Food Allergy

Nutrients, 2022
As of late, evidence has been emerging that the Maillard reaction (MR, also referred to as glycation) affects the structure and function of food proteins.
Daniela Briceno Noriega, H. E. Zenker, Cresci-Anne Croes, Arifa Ewaz, J. Ruinemans-Koerts, H. Savelkoul, R. V. van Neerven, M. Teodorowicz   +7 more
semanticscholar   +1 more source

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

, 2017
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction.
Angelini, Francesco, Bordin, Antonella, Carrizzo, Albino, Chimenti, Isotta, DE FALCO, Elena, Forte, Maurizio, Frati, Giacomo, Nocella, Cristina, Pagano, Francesca, Palmerio, Silvia, Schiavon, Sonia, Schirone, Leonardo, Sciarretta, Sebastiano, Valenti, Valentina, Vecchione, Carmine, Yee, Derek   +15 more
core   +10 more sources

N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression*

Journal of Biological Chemistry, 1999
Recent studies suggested that interruption of the interaction of advanced glycation end products (AGEs), with the signal-transducing receptor receptor for AGE (RAGE), by administration of the soluble, extracellular ligand-binding domain of RAGE, reversed
T. Kislinger, Caifeng Fu, Birgit Huber, W. Qu, A. Taguchi, S. Du Yan, M. Hofmann, S. Yan, M. Pischetsrieder, D. Stern, A. Schmidt   +10 more
semanticscholar   +1 more source

Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]

, 2019
Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G, Bordea, Roxana, Boșca, Bianca A, Băbțan, Anida-Maria, Câmpian, Radu S, Feurdean, Claudia N, Ilea, Aranka, Ionel, Anca, Miclăuș, Viorel, Mirică, Codruța I, Petrescu, Nausica B, Ruxanda, Flavia, Todea, Adina D, Uriciuc, Willi A   +13 more
core   +2 more sources

Circulating levels of soluble receptor for advanced glycation end products and ligands of the receptor for advanced glycation end products in patients with acute liver failure [PDF]

Liver Transplantation, 2015
Animal studies suggest that receptor for advanced glycation end products (RAGE)–dependent mechanisms contribute to acetaminophen‐induced liver damage. We examined whether circulating levels of soluble receptor for advanced glycation end products (sRAGE) or RAGE ligands, including extracellular newly identified receptor for advanced glycation end ...
Basta G, Del Turco S, Navarra T, Lee WM
openaire   +4 more sources

Elevated level of the soluble receptor for advanced glycation end-products involved in sarcopenia: an observational study

BMC Geriatrics, 2021
Background The soluble receptor for advanced glycation end products (sRAGE) has been proposed to serve as a marker for disease severity, but its role in sarcopenia, an age-related progressive loss of muscle mass and function, remains elusive.
Shou-En Wu, Yi-Lin Chiu, Tung-Wei Kao, Wei-Liang Chen   +3 more
doaj   +1 more source