Results 211 to 220 of about 156,578 (338)

Clonal Hematopoiesis and Thrombosis

American Journal of Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
wiley   +1 more source

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

, 1998
Björn Hock, Beatrix Böhme, Thomas Karn, Takaharu Yamamoto, Kozo Kaibuchi, Uwe Holtrich, Sacha J. Holland, Tony Pawson, Helga Rübsamen‐Waigmann, Klaus Strebhardt   +9 more
openalex   +1 more source

Expanding the Tyrosine Kinase Domain of CSF1R? A Case Report From an Adult‐Onset Leukoencephalopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Adult‐onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), also termed hereditary diffuse leukoencephalopathy with spheroids‐1 (HDLS1), results from mutations in the CSF1R gene and leads to progressive leukoencephalopathy.
Piervito Lopriore, Gianmichele Migaleddu, Pei‐Chien Tsai, Antonella Fogli, Maria Adelaide Caligo, Gabriele Siciliano, Mirco Cosottini, Yi‐Chung Lee, Yi‐Chu Liao, Michelangelo Mancuso, Roberto Ceravolo, Daniela Frosini   +11 more
wiley   +1 more source

A Structural Insight Into Two Important ErbB Receptors (EGFR and HER2) and Their Relevance to Non-Small Cell Lung Cancer. [PDF]

Arch Pharm (Weinheim)
Topalan E, Büyükgüngör A, Çiğdem M, Güra S, Sever B, Otsuka M, Fujita M, Demirci H, Ciftci H.   +8 more
europepmc   +1 more source

Signaling Complexes and Protein-Protein Interactions Involved in the Activation of the Ras and Phosphatidylinositol 3-Kinase Pathways by the c-Ret Receptor Tyrosine Kinase [PDF]

, 2000
Valérie Besset, Rizaldy P. Scott, Carlos F. Ibáñez   +2 more
openalex   +1 more source

The role of protein phosphorylation modifications mediated by iron metabolism regulatory networks in the pathogenesis of Alzheimer's disease. [PDF]

Front Aging Neurosci
Liu FX, Yang SZ, Shi KK, Li DM, Song JB, Sun L, Dang X, Li JY, Deng ZQ, Zhao M, Feng YC.   +10 more
europepmc   +1 more source

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

Navigating TAM receptor dynamics in tumour immunotherapy. [PDF]

Cancer Immunol Immunother
Yang J, Chen G, Wang R, Song C, Yi H.
europepmc   +1 more source

Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance.

, 1995
Jia-Ying Bu, Andréy S. Shaw, Andrew C. Chan   +2 more
openalex   +1 more source

Sprouty Proteins Are Targeted to Membrane Ruffles upon Growth Factor Receptor Tyrosine Kinase Activation [PDF]

, 2000
Jormay Lim, Esther Sook Miin Wong, Siew Hwa Ong, Permeen Yusoff, Boon Chuan Low, Graeme R. Guy   +5 more
openalex   +1 more source