Results 151 to 160 of about 2,321,962 (333)
Detection in Molecular Communications with Ligand Receptors under Molecular Interference [PDF]
arXiv, 2020 Molecular Communications (MC) is a bio-inspired communication technique that uses molecules to transfer information among bio-nano devices. In this paper, we focus on the detection problem for biological MC receivers employing ligand receptors to infer the transmitted messages encoded into the concentration of molecules, i.e., ligands.
arxiv
Glia, EarlyView.Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain. ABSTRACT Astrocytes are the most abundant glial cell type in the central nervous system (CNS).
Xiaoran Wei +2 more
wiley +1 more source
Instantons in the working memory: implications for schizophrenia [PDF]
arXiv, 1999 The influence of the synaptic channel properties on the stability of delayed activity maintained by recurrent neural network is studied. The duration of excitatory post-synaptic current (EPSC) is shown to be essential for the global stability of the delayed response.
arxiv
Intracellular machinery for the transport of AMPA receptors [PDF]
British Journal of Pharmacology, 2008 AMPA‐type glutamate receptors are one of the most dynamic components of excitatory synapses. Their regulated addition and removal from synapses leads to long‐lasting forms of synaptic plasticity, known as long‐term potentiation (LTP) and long‐term depression (LTD).
openaire +5 more sources
Neuroscience ResearchNMDA and AMPA receptors are co-localized at most glutamatergic synapses, where their numbers and distribution undergo dynamic changes. Glutamate binds to both the NMDA and AMPA receptors.
Qingchen Guo
doaj
Neuroprotection, EarlyView.Downregulation of the expression of silent information regulator sirtuin 1 (SIRT1) exacerbates neuronal degeneration and loss by activating forkhead box O1 (FOXO1) acetylation and promoting endoplasmic reticulum stress (ERSA)‐mediated apoptosis in aging.
Nan Zhang +20 more
wiley +1 more source
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014 Examined 12 patients with gliomas of the big hemispheres of a brain. Used immunoenzyme method for semiquantitative determination of the level of autoantibodies to NR2A-subunit of NMDA- and GluR1-subunit of AMPA-receptors of glutamate.
V. N. Ochkolyas, G. V. Kataeva
doaj +1 more source
In a Pickle: Is Cornichon Just Relish or Part of the Main Dish? [PDF]
, 2010 The recent discovery that vertebrate homologs of Drosophila cornichon associate with AMPA receptors led to the unexpected notion that cornichons play a role in synaptic transmission. In this issue of Neuron, Kato et al.
Brockie, Penelope J., Maricq, Andres V.
core +1 more source
Revisiting AMPA Receptors as an Antiepileptic Drug Target
Epilepsy Currents, 2011 In the 1990s there was intense interest in ionotropic glutamate receptors as therapeutic targets for diverse neurological disorders, including epilepsy.
M. Rogawski
semanticscholar +1 more source
Calcium-Permeable AMPA Receptors in the Retina [PDF]
Frontiers in Molecular Neuroscience, 2011 The retina transforms light entering the eye into a sophisticated neural representation of our visual world. Specialized synapses, cells, and circuits in the retina have evolved to encode luminance, contrast, motion, and other complex visual features. Although a great deal has been learned about the cellular morphology and circuitry that underlies this
openaire +4 more sources