Results 11 to 20 of about 42,075 (217)

Activation of acid‐sensing ion channels by carbon dioxide regulates amygdala synaptic protein degradation in memory reconsolidation

open access: yesMolecular Brain, 2021
Reconsolidation has been considered a process in which a consolidated memory is turned into a labile stage. Within the reconsolidation window, the labile memory can be either erased or strengthened.
Boren Lin   +9 more
doaj   +1 more source

Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL [PDF]

open access: yes, 2004
The efficacy of excitatory transmission in the brain depends to a large extent on synaptic AMPA receptors, hence the importance of understanding the delivery and recycling of the receptors at the synaptic sites.
Dittgen, T.   +11 more
core   +1 more source

Interaction of GABA and Excitatory Amino Acids in the Basolateral Amygdala: Role in Cardiovascular Regulation [PDF]

open access: yes, 1997
Activation of the amygdala in rats produces cardiovascular changes that include increases in heart rate and arterial pressure as well as behavioral changes characteristic of emotional arousal.
Cook, Jennifer C.   +3 more
core   +2 more sources

AMPA receptors and their minions: auxiliary proteins in AMPA receptor trafficking [PDF]

open access: yesCellular and Molecular Life Sciences, 2019
To correctly transfer information, neuronal networks need to continuously adjust their synaptic strength to extrinsic stimuli. This ability, termed synaptic plasticity, is at the heart of their function and is, thus, tightly regulated. In glutamatergic neurons, synaptic strength is controlled by the number and function of AMPA receptors at the ...
Diane Bissen   +2 more
openaire   +3 more sources

AMPA Receptor-Mediated Ca2+ Transients in Mouse Olfactory Ensheathing Cells

open access: yesFrontiers in Cellular Neuroscience, 2019
Ca2+ signaling in glial cells is primarily triggered by metabotropic pathways and the subsequent Ca2+ release from internal Ca2+ stores. However, there is upcoming evidence that various ion channels might also initiate Ca2+ rises in glial cells by Ca2 ...
Antonia Beiersdorfer, Christian Lohr
doaj   +1 more source

p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression

open access: yesNature Communications, 2019
AMPA receptors mediate excitatory synaptic transmission and are involved in synaptic plasticity. The authors show that p97 interacts with the GluA1 subunit of AMPA receptors, promotes the formation of GluA1 homomeric AMPA receptors, and regulates AMPA ...
Yuan Ge   +10 more
doaj   +1 more source

GluA2-lacking AMPA receptors in hippocampal CA1 cell synapses: evidence from gene-targeted mice

open access: yesFrontiers in Molecular Neuroscience, 2012
The GluA2 subunit in heteromeric AMPA receptor channels restricts Ca2+ permeability and block by polyamines, rendering linear the current-voltage relationship of these glutamate-gated cation channels.
Andrei eRozov   +2 more
doaj   +1 more source

Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons [PDF]

open access: yes, 2006
We examined the effects of the chemokine fractalkine (CX3CL1) on EPSCs evoked by electrical stimulation of Schaffer collaterals in patch-clamped CA1 pyramidal neurons from rat hippocampal slices.
BERTOLLINI, Cristina   +8 more
core   +1 more source

Synapse elimination and learning rules co-regulated by MHC class I H2-Db. [PDF]

open access: yes, 2014
The formation of precise connections between retina and lateral geniculate nucleus (LGN) involves the activity-dependent elimination of some synapses, with strengthening and retention of others. Here we show that the major histocompatibility complex (MHC)
Adelson, Jaimie   +7 more
core   +3 more sources

Selective disruption of stimulus-reward learning in glutamate receptor gria 1 knockout mice. [PDF]

open access: yes, 2003
Glutamatergic neurotransmission via AMPA receptors has been an important focus of studies investigating neuronal plasticity. AMPA receptor glutamate receptor 1 (GluR1) subunits play a critical role in long-term potentiation (LTP).
Mead, Andy N, Stephens, David N
core   +2 more sources

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