Androgen Receptors in Human Breast Cancer and Female Canine Mammary Tumors [PDF]
MoleculesThis review explores the potential role of androgens in human breast cancer and female canine mammary tumors. Human breast cancer is one of the most common cancers affecting women globally, while female canine mammary tumors provide a natural model for ...
Vladimir Vidović +5 more
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Membrane testosterone binding sites in prostate carcinoma as a potential new marker and therapeutic target: Study in paraffin tissue sections [PDF]
BMC Cancer, 2005 Background Steroid action is mediated, in addition to classical intracellular receptors, by recently identified membrane sites, that generate rapid non-genomic effects.
Theodoropoulos Panayiotis A +8 more
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The Effect of Estradiol and Testosterone Levels Alone or in Combination with Their Receptors in Predicting the Severity of Systemic Lupus Erythematosus: A Cohort Study [PDF]
Iranian Journal of Medical SciencesBackground: Developing a practical method to predict active systemic lupus erythematosus (SLE) in patients with inactive/mild status at the onset of the disease could lead to appropriate treatment that ultimately prevents future relapses. The development
Samaneh Abdolahpour +4 more
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Clinical and morphological features of peptic ulcer at men and women [PDF]
Саратовский научно-медицинский журнал, 2010 The aim of research was to study clinical and morphological features of peptic ulcer at men and women of various age. 166 patients with duodenal peptic ulcer (80 men and 86 women) and 138 with stomach peptic ulcer (80 men and 58 women) were inspected ...
Islamova Е.А., Lipatova Т.Е.
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Androgen receptor expression in hypospadias
Journal of Indian Association of Pediatric Surgeons, 2020 Introduction: The exact mechanism behind the development of hypospadias is unclear. Research studies on androgen receptor (AR) expression are controversial with results stating all possible outcomes – AR elevated, similar, or reduced when compared to ...
Dhanvanth Rajesh Balaji +8 more
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Endocrine-Disrupting Activities of Flavones on Steroid Receptors: Structural Requirements and Synthesis of Novel Flavone with Improved Estrogenic Activity [PDF]
BiomedicinesBackground/Objectives: Flavonoids are common ubiquitous components of plants and are consumed by humans and livestock in their diets. Many different activities have been proposed for a variety of flavonoids that play a role in the benefits of a plant ...
Steven K. Nordeen +5 more
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Androgen regulation of the androgen receptor coregulators [PDF]
BMC Cancer, 2008 Abstract Background The critical role of the androgen receptor (AR) in the development of prostate cancer is well recognized. The transcriptional activity of AR is partly regulated by coregulatory proteins. It has been suggested that these coregulators could also be important in the progression of prostate cancer. The
Urbanucci, Alfonso +4 more
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Molecules, 2021 Flavonoids are plant bioactives that are recognized as hormone-like polyphenols because of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their estrogen- and androgen-like activity. Most efforts to verify flavonoid
Giulia D’Arrigo +5 more
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Androgen Receptor Phosphorylation [PDF]
Endocrine Research, 1993 Phosphorylation of transcription factors plays an important role in regulation of gene expression. DNA-binding, transactivation activity, and subcellular trafficking of specific transcription factors have been shown to be regulated by phosphorylation/dephosphorylation.
Leen J. Blok +2 more
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Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma
Zhongliu Fangzhi Yanjiu, 2023 Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1.
WANG Ruihua +4 more
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