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Prognostic Value of Androgen Receptor Expression in Bladder Tumors [PDF]

open access: yesTranslational Research in Urology, 2023
Introduction: The present study was conducted with the aim of investigating the prognostic value of androgen receptor expression in bladder tumors.Methods: This study was conducted in the urology department of Imam Reza Hospital on male patients with ...
Salman Soltani   +8 more
doaj   +1 more source

Androgen Receptor Phosphorylation [PDF]

open access: yesEndocrine Research, 1993
Phosphorylation of transcription factors plays an important role in regulation of gene expression. DNA-binding, transactivation activity, and subcellular trafficking of specific transcription factors have been shown to be regulated by phosphorylation/dephosphorylation.
L J, Blok   +2 more
openaire   +3 more sources

Androgen receptor mutations [PDF]

open access: yesThe Journal of Steroid Biochemistry and Molecular Biology, 1995
Male sexual differentiation and development proceed under direct control of androgens. Androgen action is mediated by the intracellular androgen receptor, which belongs to the superfamily of ligand-dependent transcription factors. At least three pathological situations are associated with abnormal androgen receptor structure and function: androgen ...
Brinkmann, A. O.   +6 more
openaire   +3 more sources

Binding of Androgen- and Estrogen-Like Flavonoids to Their Cognate (Non)Nuclear Receptors: A Comparison by Computational Prediction

open access: yesMolecules, 2021
Flavonoids are plant bioactives that are recognized as hormone-like polyphenols because of their similarity to the endogenous sex steroids 17β-estradiol and testosterone, and to their estrogen- and androgen-like activity. Most efforts to verify flavonoid
Giulia D’Arrigo   +5 more
doaj   +1 more source

Androgen receptor abnormalities [PDF]

open access: yesThe Journal of Steroid Biochemistry and Molecular Biology, 1991
The human androgen receptor is a member of the superfamily of steroid hormone receptors. Proper functioning of this protein is a prerequisite for normal male sexual differentiation and development. The cloning of the human androgen receptor cDNA and the elucidation of the genomic organization of the corresponding gene has enabled us to study androgen ...
Brinkmann, A. O.   +9 more
openaire   +2 more sources

Research Progress of Androgen/Androgen Receptor Signaling Pathway in Hepatocellular Carcinoma

open access: yesZhongliu Fangzhi Yanjiu, 2023
Hepatocellular carcinoma (HCC) is a kind of primary liver cancer with a high mortality rate. In China, the incidence ratio in males to females with HCC is 2:1–5:1.
WANG Ruihua   +4 more
doaj   +1 more source

Androgen and Estrogen Receptor Expression in Different Types of Perianal Gland Tumors in Male Dogs

open access: yesAnimals, 2021
Perianal gland tumors are modified sebaceous glands present in the skin of the perianal region in the dog. Hormonal stimulation may induce hyperplasia of the perianal glands or their neoplastic progression. The presence of androgen (AR) and estrogen (ER)
Adam Brodzki   +6 more
doaj   +1 more source

Membrane testosterone binding sites in prostate carcinoma as a potential new marker and therapeutic target: Study in paraffin tissue sections

open access: yesBMC Cancer, 2005
Background Steroid action is mediated, in addition to classical intracellular receptors, by recently identified membrane sites, that generate rapid non-genomic effects.
Theodoropoulos Panayiotis A   +8 more
doaj   +1 more source

Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia [PDF]

open access: yesEndocrinology and Metabolism, 2015
Gynecomastia is a benign enlargement of the male breast caused by the proliferation of glandular breast tissue. Determining the various causes of gynecomastia such as physiological causes, drugs, systemic diseases, and endocrine disorders is important ...
Sung Won Lee   +10 more
doaj   +1 more source

Immunohistochemical expression of androgen receptors in prostate carcinoma and benign prostatic hyperplasia [PDF]

open access: yesVojnosanitetski Pregled, 2020
Background/Aim. Prostate carcinoma (PCa) and its parent organ are influenced by hormones, which is used for therapeutic purposes. Through androgen receptors (AR) androgens influence cell growth and function, proliferation, differentiation, apoptosis ...
Trivunić-Dajko Sandra   +4 more
doaj   +1 more source

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