Results 91 to 100 of about 78,719 (215)
Silent Spring - the lost call [PDF]
The "silence" in Rachel Carson's Silent Spring1 alludes to the demise of bird populations through reproductive problems and death resulting from exposure to the pesticides of that time, many of which are endocrine active.
Mary Ann Ottinger, Michael J. Quinn
core +1 more source
The impacts of gender differences on systemic lupus erythematosus and lupus nephritis
Systemic lupus erythematosus is a common autoimmune disease,and lupus nephritis is one of its common complications. Their clinical manifestations have differences. The incidence ratio of male to female varies by age group.
LI Chun-hong, TIAN Jie
doaj
Objective: To investigate the potential of N-acetylcysteine (NAC) and zinc sulphate (ZnSO4) in mitigating reproductive dysfunction caused by di-2-ethylhexyl phthalate (DEHP) in rats and to understand the underlying mechanisms, specifically oxidative ...
Victor Oghenekparobo Emojevwe +9 more
doaj +1 more source
Molecular Defects of the Androgen Receptor
Defects of the androgen receptor cause a wide spectrum of abnormalities of phenotypic male development, ranging from individuals with mild defects of virilization to those with complete female phenotypes. In parallel with this phenotypic spectrum, a large number of different mutations have been identified that alter the synthesis or functional activity
openaire +3 more sources
Engineered antibody and neuropeptide mediated radionuclide targeting in prostate cancer [PDF]
PhDProstate cancer (PC) is the most common cancer type in men in the western world and to date no definitive stratergy to image PC is avaliable. This thesis explores the possibility of using Prostate Specific Membrane Antigen (PSMA) and Gastrin Releasing
Kashani, Roxana M G +1 more
core
Hormone Receptors in Cervicovaginal Cells
Some parts of the female reproductive system such as vagina and ectocervix is covered with stratified squamous epithelium (SSE). SSE consists of many layers and steroid hormones are essential for its normal growth and development.
Şayeste Demirezen +2 more
doaj
Testosterone and its active metabolite dihydrotestosterone exert their influence on target cells through a specific intracellular protein receptor. Structural abnormalities of this receptor lead to a diminished androgen action within the cell and result ...
Berkovitz, Gary D +2 more
core +1 more source
A concise review of testosterone and bone health
Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman, Kok-Yong Chin Department of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lampur, Malaysia Abstract: Osteoporosis is a condition causing significant morbidity and mortality in the elderly
Mohamad NV, Soelaiman IN, Chin KY
doaj
Androgen receptor dysfunction in human androgen insensitivity
The androgen insensitivity syndromes comprise a spectrum of phenotypic abnormalities in male sex differentiation and development that result from target tissue resistance to androgen action due to molecular lesions in the X-chromosome-linked androgen receptor gene.
openaire +2 more sources
3D model of amphioxus steroid receptor complexed with estradiol [PDF]
The origins of signaling by vertebrate steroids are not fully understood. An important advance was the report that an estrogen-binding steroid receptor [SR] is present in amphioxus, a basal chordate with a similar body plan as vertebrates.
Michael E. Baker, David J. Chang
core +1 more source

