Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors [PDF]
Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids ...
Michael E. Baker
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The localization of androgen receptors in human bone. [PDF]
Androgens have important effects on the human skeleton, and deficiency has been associated with bone loss in both males and females. The skeletal actions of androgens may be mediated directly via the androgen receptor (AR) or indirectly via the estrogen ...
Kusec, V +5 more
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A study of androgen and estrogen receptors α, β in skin tags
Background: In women, the age of 50 is suggested to be the turning point of life at which the development of skin tags comes to a stop. A major event that occurs around this period of life is menopause/andropause.
El Safoury Omar +2 more
doaj
Hormone receptors of the baboon cardiovascular system. Biochemical characterization of aortic cytoplasmic androgen receptors. [PDF]
Cytoplasmic androgen receptors were identified in the aorta of the baboon (Papio sp.). Using the synthetic androgen R1881 (17 beta-hydroxy-17 alpha-methyl-estra-4,9,11-trien-3-one) as probe, androgen receptors were demonstrated only when the incubation ...
A L Lin, H C McGill, S A Shain
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Immunocytochemical Localization of Androgen Receptors in Human Skin Using Monoclonal Antibodies Against the Androgen Receptors [PDF]
Androgen receptors were localized in cryostat sections of human skin using monoclonal antibodies to the human androgen receptor. Bound antibodies were detected using biotinylated rabbit anti-rat IgG, peroxidase-conjugated streptavidin, and ...
Soltani, Keyoumars +6 more
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Sex Hormones and Their Receptors Regulate Liver Energy Homeostasis
The liver is one of the most essential organs involved in the regulation of energy homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated with imbalance between lipid formation and breakdown, glucose production and ...
Minqian Shen, Haifei Shi
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A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors [PDF]
Despite their physiological importance, selective interactions between Nuclear Receptors (NRs) and their cofactors are poorly understood. Here we describe a novel signature motif (F/YSXXLXXL/Y) in the developmental regulator BCL11A that facilitates its ...
Fulton, J +17 more
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Expression of estrogen and androgen receptors in children with hypospadias: Preliminary report [PDF]
This investigation was conducted to evaluate the presence of estrogen and androgen receptors in penile tissues of patients with hypospadias. The biopsy specimens from prepuce, glans, and urethral plate were sampled during the hypospadias surgery in five ...
DERVISOGLU, Sergülen +4 more
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Detection of Androgen Receptors by Flow Cytometry [PDF]
Dutta, Mayurika, ‘Detection of androgen receptors by Flow Cytometry’. Internship Practicum report, Biotechnology, May 2008, 80 pp., 1 table, 18 figures. The use of androgen therapy is expanding given the documented potential benefits like increasing bone
Dutta, Mayurika
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Androgen and estrogen receptors in perinatal ferret brain [PDF]
Using DNA-cellulose affinity chromatography and either 3H-labeled dihydrotestosterone, testosterone, or estradiol, we qualitatively and quantitatively analyzed the androgen- and estrogen-binding activities present in four regions of male and female ...
MJ Baum, TO Fox, C Bloom, CC Vito
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