Results 41 to 50 of about 177,905 (190)
Background/aims The renin-angiotensin system (RAS) is altered in Parkinson’s disease (PD), a disease due to substantia nigra neurodegeneration and whose dopamine-replacement therapy, using the precursor levodopa, leads to dyskinesias as the main side ...
Rafael Rivas-Santisteban +6 more
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Angiotensin II (AngII) is the biologically active peptide of the renin-angiotensin system (RAS). Tissue- based, local RAS has been identified in the prostate, testis, epididymis and coagulating glands.
Kamila Domińska +5 more
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Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]
Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO +4 more
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Angiotensin Receptor Blockers [PDF]
Angiotensin receptor blockers (also known as ARBs) are a class of medications that are widely used by patients with high blood pressure, kidney disease, and heart failure. This article provides information for patients who receive this type of medication.
M Ruilope, Massimo Volpe
openaire +2 more sources
In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells
Low back pain is a clinically highly relevant musculoskeletal burden and is associated with inflammatory as well as degenerative processes of the intervertebral disc.
Babak Saravi +9 more
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Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia +3 more
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Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
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Pathophysiological Role of Caveolae in Hypertension [PDF]
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver +4 more
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ISN Forefronts Symposium 2015: Nuclear Receptors and Diabetic Nephropathy
Diabetic nephropathy (DN) is the major reason for end-stage renal disease in the Western world. Patients with DN developed more severe cardiovascular complications with worse prognosis.
Bo Zheng, Lei Chen, Frank J. Gonzalez
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Vascular reactivity experiments using isolated aortic rings have been widely used as a model for physiological and pharmacological studies since the early sixties.
Marcos André Soares Leal +5 more
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