Results 41 to 50 of about 177,905 (190)

Angiotensin AT1 and AT2 receptor heteromer expression in the hemilesioned rat model of Parkinson’s disease that increases with levodopa-induced dyskinesia

open access: yesJournal of Neuroinflammation, 2020
Background/aims The renin-angiotensin system (RAS) is altered in Parkinson’s disease (PD), a disease due to substantia nigra neurodegeneration and whose dopamine-replacement therapy, using the precursor levodopa, leads to dyskinesias as the main side ...
Rafael Rivas-Santisteban   +6 more
doaj   +1 more source

Influence of myocardial infarction on changes in the expression of angiotensin type 1 receptor in the rat prostate

open access: yesFolia Histochemica et Cytobiologica, 2011
Angiotensin II (AngII) is the biologically active peptide of the renin-angiotensin system (RAS). Tissue- based, local RAS has been identified in the prostate, testis, epididymis and coagulating glands.
Kamila Domińska   +5 more
doaj   +1 more source

Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]

open access: yes, 2010
Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO   +4 more
core   +1 more source

Angiotensin Receptor Blockers [PDF]

open access: yesHigh Blood Pressure & Cardiovascular Prevention, 2003
Angiotensin receptor blockers (also known as ARBs) are a class of medications that are widely used by patients with high blood pressure, kidney disease, and heart failure. This article provides information for patients who receive this type of medication.
M Ruilope, Massimo Volpe
openaire   +2 more sources

In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells

open access: yesCells, 2022
Low back pain is a clinically highly relevant musculoskeletal burden and is associated with inflammatory as well as degenerative processes of the intervertebral disc.
Babak Saravi   +9 more
doaj   +1 more source

Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]

open access: yes, 2014
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia   +3 more
core   +1 more source

Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]

open access: yes, 2014
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core   +3 more sources

Pathophysiological Role of Caveolae in Hypertension [PDF]

open access: yes, 2019
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver   +4 more
core   +2 more sources

ISN Forefronts Symposium 2015: Nuclear Receptors and Diabetic Nephropathy

open access: yesKidney International Reports, 2016
Diabetic nephropathy (DN) is the major reason for end-stage renal disease in the Western world. Patients with DN developed more severe cardiovascular complications with worse prognosis.
Bo Zheng, Lei Chen, Frank J. Gonzalez
doaj   +1 more source

Physiological and Biochemical Vascular Reactivity Parameters of Angiotensin II and the Action of Biased Agonist TRV023

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2020
Vascular reactivity experiments using isolated aortic rings have been widely used as a model for physiological and pharmacological studies since the early sixties.
Marcos André Soares Leal   +5 more
doaj   +1 more source

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