Results 181 to 190 of about 132,216 (243)

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

open access: yesAdvanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao   +7 more
wiley   +1 more source

B cells enable autoreactive T cells to avoid suppression. [PDF]

open access: yesProc Natl Acad Sci U S A
Funsten M   +8 more
europepmc   +1 more source

Immune podocyte injury in autoimmune glomerular diseases. [PDF]

open access: yesFront Immunol
Zhu H, Sun J, Yan Y, Liu P, Huang Y.
europepmc   +1 more source

Home - About - Disclaimer - Privacy