Results 111 to 120 of about 59,671 (227)

Inflammation and mechanical force‐induced bone remodeling

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon   +6 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez   +6 more
wiley   +1 more source

Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]

open access: yes, 2016
Cooper, Andrea   +3 more
core   +2 more sources

From Infection to Anxiety: A Sequential Model Linking Latent Toxoplasmosis to Psychological Distress via Health and Stress

open access: yesScandinavian Journal of Psychology, EarlyView.
ABSTRACT Identifying the drivers of chronic stress is crucial for understanding its impact on mental health. Latent toxoplasmosis, a widespread parasitic infection, has been linked to various psychological changes. The Stress‐Coping Hypothesis proposes that at least some of these changes are consequences of chronic stress arising from the infection's ...
Jaroslav Flegr   +2 more
wiley   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya   +22 more
wiley   +1 more source

A Cross‐Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker

open access: yesGlia, Volume 74, Issue 6, June 2026.
Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma   +6 more
wiley   +1 more source

The role of hypoxia and complement receptor 2 or toll-like receptor 2 on B1 B cell effector function [PDF]

open access: yes
Master of ScienceDivision of BiologySherry D. FlemingProfessional phagocytes play a critical role in maintaining homeostasis within a host through phagocytic, microbicidal, and inflammatory activity.
Knights, Kaori
core   +1 more source

Predicting SARS‐CoV‐2 Infection With Graph Attention Capsule Networks

open access: yesComputational Intelligence, Volume 42, Issue 3, June 2026.
ABSTRACT Recent studies in machine learning have demonstrated the effectiveness of applying graph neural networks (GNNs) to single‐cell RNA sequencing (scRNA‐seq) data to predict COVID‐19 disease states. In this study, we propose an explainable graph attention capsule network (GACapNet), which extracts and fuses Severe Acute Respiratory Syndrome ...
Runjie Zhu   +4 more
wiley   +1 more source

Analysis of Somatic Mutations and Immunotherapy Biomarkers in Chinese Patients With Non‐Small Cell Lung Cancer During 2019–2024: A Retrospective Study

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Understanding genetic alterations in lung cancer remains challenging due to tumor heterogeneity and malignancy. This study aimed to investigate somatic variations and immune‐related biomarkers in Chinese patients with NSCLC.
Xiumei Liu   +6 more
wiley   +1 more source

Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies

open access: yesMedComm, Volume 7, Issue 5, May 2026.
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He   +9 more
wiley   +1 more source

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