Results 121 to 130 of about 59,671 (227)

Contrasting roles for IKK-regulated inflammatory signalling pathways for development and maintenance of type 1 and adaptive γδ T cells. [PDF]

Elife
Islam F, Williams C, Hogan T, Webb LV, Boal-Carvalho I, Seddon B.   +5 more
europepmc   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Genetic engineering and allogeneic optimization of Vδ1 γδ CAR-T cells (ADI-270) for cancer immunotherapy. [PDF]

J Immunother Cancer
Liu W, Moriarity BS, Webber BR.
europepmc   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

A Decade of cGAS Discovery: Point of Convergence in Oral Diseases. [PDF]

Int Dent J
Sun L, Gao P, Xiao P, Li S, Liu D.
europepmc   +1 more source

Strong‐Gradient Diffusion‐Weighted Imaging of Prostate Cancer Using an Inside‐Out Nonlinear Gradient Coil

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2671-2688, May 2026.
ABSTRACT Purpose To demonstrate improved image quality and lesion conspicuity in prostate diffusion‐weighted imaging (DWI) using an inside‐out nonlinear gradient coil that provides locally strong gradients (200–500 500 mT/m) at typical prostate positions.
Horace Z. Zhang, Nahla M. H. Elsaid, Terence W. Nixon, Andrew Dewdney, Dana C. Peters, Jeffrey C. Weinreb, Preston C. Sprenkle, R. Todd Constable, Gigi Galiana   +8 more
wiley   +1 more source

The Phylogenomic Approach Suggests That Butyrophilins Have Ligands Beyond Gamma-Delta Receptors. [PDF]

Int J Mol Sci
Marenco L, Olive D, Pontarotti P.
europepmc   +1 more source

SARS‐CoV‐2 Variants and Immune Evasion: Mapping the Future of Vaccine Design

Reviews in Medical Virology, Volume 36, Issue 3, May 2026.
ABSTRACT The evolutionary trajectory of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) has progressed through several distinct phases since its zoonotic emergence, transitioning from initial human adaptation to an era of rapid antigenic drift and complex immune evasion. As of early 2026, the global landscape is dominated by highly evolved
Fatih Uzer, Fulya Erendor, Salih Sanlioglu   +2 more
wiley   +1 more source

Cellular therapies for rheumatic disease. [PDF]

Curr Opin Rheumatol
Koumpouras F, Caricchio R.
europepmc   +1 more source

From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki, Minahil Sharjeel, Jennifer E. Cowan   +2 more
wiley   +1 more source