Results 141 to 150 of about 15,411,883 (261)

Nasal <i>Streptococcus pyogenes</i> Infection Exacerbates Psoriasiform Relapse in Mice Through TLR2-Dependent Dendritic Cell Metabolic Reprogramming and γδ T Cell Activation. [PDF]

J Inflamm Res
Zhou L, Wang Z, Zhao J, Di T, Meng Y, Zhu H, Ma Y, Yu X, Liu W, Su Y, Li L, Li P, Wang Y.   +12 more
europepmc   +1 more source

Exploratory single‐nucleus multiomics analysis of myeloid cell states associated with neoadjuvant chemotherapy response in pancreatic ductal adenocarcinoma

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Neoadjuvant‐treated PDAC tumors were stratified into responders and non‐responders based on CAP guidelines snRNA‐seq, snATAC‐seq, and spatial transcriptomics can be used to profile the neoadjuvant‐chemotherapy‐treated PDAC immune landscape. Our exploratory findings nominate candidate myeloid features for validation in larger cohorts and functional ...
Mercy Ojetunde, Li Ma, Hillary G. Goodney, Alyson M. Stevens, Alan Mizener, Emidio E. Pistilli, Sascha Ott, Kawther Abdilleh, Barbara Szomolay, Gangqing Hu, Timothy D. Eubank, Brian A. Boone   +11 more
wiley   +1 more source

DLL3-Targeted Strategies in Advanced Prostate Cancer: Current Evidence and Future Perspectives. [PDF]

Drugs
Pecoraro G, De Giorgi A, Montelatici G, Salfi G, Lin HM, Turco F, Taha T, Beltran H, de Bono J, Aggarwal RR, von Amsberg G, Joerger M, Imbimbo M, Colombo I, Gillessen S, Pedrani M.   +15 more
europepmc   +1 more source

Multi‐site sequencing supports dual‐track evolution and identifies candidate metastasis‐associated factors in gastric cancer ovarian metastasis

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Multi‐site whole‐exome sequencing and phylogenetic reconstruction characterise gastric cancer ovarian metastasis. Lymph node‐dependent and lymph node‐independent evolutionary patterns coexist across patients. SCAF4 is nominated as a candidate metastasis‐associated factor supported by genomic and loss‐of‐function evidence.
Peiyu Zhu, Xiaofang Xing, Ke Ji, Lingqian Wang, Zhongwu Li, Shuqin Jia, Longtao Huangfu, Xiaomei Li, Biao Fan, Zhaode Bu, Jiafu Ji   +10 more
wiley   +1 more source

Celiac Disease: Cytokine Profile of Intraepithelial Gamma Delta T Cells in Disease Severity. [PDF]

Cells
Mazzarella G, Iacomino G, Iaquinto G, Camarca A, Picariello E, Melina R, Rotondi Aufiero V.   +6 more
europepmc   +1 more source

B‐Cell Remodeling and Regulatory Phenotypes During Acute COVID‐19 Are Unaffected by Polyclonal Anti‐SARS‐CoV‐2 Antibody XAV‐19

European Journal of Immunology, Volume 56, Issue 9, September 2026.
SARS‐CoV‐2 infection drives transient B‐cell remodeling toward an activated, regulatory‐like phenotype. In this randomized sub‐study, the polyclonal neutralizing antibody XAV‐19 did not detectably alter B‐cell phenotype, transcriptome, or function relative to placebo, indicating that passive polyclonal therapy preserves B‐cell homeostasis during acute ...
Nicolas Degauque, Richard Danger, Hoa Le Mai, Marion Cadoux, Thi‐Van‐Ha Nguyen, Gaëlle Tilly, François Raffi, Thomas Guimard, Karine Lacombe, Didier Laureillard, Laurent Hocqueloux, Vincent Dubee, Florence Ader, Cynthia Fourgeux, Jérémie Poschmann, Bernard Vanhove, Odile Duvaux, Benjamin Gaborit, Sophie Brouard, POLYCOR study group   +19 more
wiley   +1 more source

Harnessing the potential of γδ T cells through engineering and combination treatment for cancer therapies. [PDF]

Nat Commun
Fisher J, Wu Y, Abate-Daga D, Barisa M, Lamb L.   +4 more
europepmc   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Translational potential of γδ T cells in hematologic diseases: from immunobiology to therapeutic innovation. [PDF]

Front Immunol
Zhou X, Zhai M, Zhang Z, Zhang G.
europepmc   +1 more source

Lactiplantibacillus plantarum BF_15 Confers Protection Against Ulcerative Colitis by Orchestrating Gut Microbiota‐Barrier‐Immune Triad Homeostasis

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Lactiplantibacillus plantarum BF_15 mitigates ulcerative colitis via modulating the triad homeostasis of gut microbiota, mucosal barrier and intestinal immunity. It restores disturbed intestinal microecology by elevating the abundance of Bacteroidetes.
Na Zhang, Hongjie Liu, Dongyao Li, Chen Li, Xinyi Ge, Hongyan Kang, Miaoshu Wang, Hongtao Tian, Xiaoyan Miao   +8 more
wiley   +1 more source