Results 131 to 140 of about 27,293 (229)

Spatial and Phenotypic Heterogeneity of ILC Subsets in Mouse Lung Under Type 2 Inflammatory Conditions

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Using cyclic multiplex microscopy in an IL‐33‐driven type 2 inflammation model, we validated a spatial workflow mapping rare lung ILCs. High‐dimensional analysis revealed a conserved peri‐lymphatic niche at early time points of inflammation where ILC2s and myeloid cells co‐localize with LYVE1+ vessels, highlighting a structured immunological ...
Sandy Kroh, Anna Pascual‐Reguant, Artür Manukyan, Ralf Uecker, Robert Günther, Lars Philipsen, Ralf Koehler, Peggy Mex, Markus Landthaler, Raluca A. Niesner, Anja E. Hauser   +10 more
wiley   +1 more source

Spatially resolved T cell receptor diversity mapping uncovers variability of the cancer immune microenvironment. [PDF]

EBioMedicine
Magoulopoulou A, Chatzinikolaou M, Metousis A, Hu T, Yu H, Zerdes I, Wang K, Foukakis T, Long M, Leandersson K, Micke P, Strell C, Nilsson M.   +12 more
europepmc   +1 more source

A Cross‐Disease Microglial Transcriptional Program Characterizes Neurodegeneration and Highlights SPP1 as a Biomarker

Glia, Volume 74, Issue 6, June 2026.
Distinct microglial subpopulations are depicted, highlighting variations in gene expression and functional roles in response to specific disease conditions and the complexity of microglial activation and differentiation in neurodegeneration. ABSTRACT Microglial cells are key players in maintaining brain homeostasis and responding to pathological ...
Alessandro Palma, Roberta Stefanelli, Francesco Trenta, Chiara Projetti, Greta Massa, Sonia Canterini, Maria Teresa Fiorenza   +6 more
wiley   +1 more source

Cellular therapies for rheumatic disease. [PDF]

Curr Opin Rheumatol
Koumpouras F, Caricchio R.
europepmc   +1 more source

Cellular Immune Response Induced by mRNA Vaccines Against SARS-CoV-2. [PDF]

Immun Inflamm Dis
Tovar V, Sánchez IP, Rugeles MT, Taborda NA, Hernandez JC.   +4 more
europepmc   +1 more source

TCRγ constant usage tunes human γδ T cell antigen sensitivity, thymic programming, and peripheral function. [PDF]

Sci Immunol
Viswanathan M, Castro CD, Broughton AE, Ramesh A, Asby N, Bergquist A, Kaiser C, Luna A, Huang J, Bissonnette M, Koh A, Hibino N, Schoettler N, Sperling A, Adams EJ.   +14 more
europepmc   +1 more source

Characterisation of tumor-infiltrating gamma-delta T cells in human colorectal cancer with MHC-I loss. [PDF]

Clin Transl Immunology
Li TA, Quigley LT, Chan KF, Williams DS, Mielke LA, Behren A, Da Gama Duarte J.   +6 more
europepmc   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak, Noor Hussein, Veronica Piedra, Saloni Malla, Chandrabose Karthikeyan, Haneen Amawi, Harish Rajak, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +9 more
wiley   +1 more source

Harnessing Vδ1⁺ T cells for next-generation immunotherapy: from mechanistic insights to clinical translation. [PDF]

Front Immunol
Wang F, Zhao J, Zhang T, Shi J.
europepmc   +1 more source

Metabolic Tagging of Tumour Extracellular Vesicles for Targeted Modulation of Dendritic Cells

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as a promising alternative to cell‐based therapies due to their benign safety profiles and favourable pharmacokinetic properties. Tumour EVs, in particular, have shown promise to function as a therapeutic cancer vaccine for various cancer types.
Rimsha Bhatta, Wenhao Xu, Ruike Dai, Yusheng Liu, Jiadiao Zhou, Yixin Xue, Hua Wang   +6 more
wiley   +1 more source