Results 151 to 160 of about 15,411,883 (261)

Loss of Major Histocompatibility Complex I and II Function in the Genome of Glacier Lanternfish Provides Insight Into Evolution of Vertebrate Immune Systems. [PDF]

Genome Biol Evol
Solbakken MH, Tørresen OK, Tooming-Klunderud A, Skage M, Bakken T, Jakobsen KS.   +5 more
europepmc   +1 more source

Lonicerae Japonicae Flos as a Dietary Natural Product: Bioactive Constituents, Gut Health Modulation, and Therapeutic Potential in Ulcerative Colitis and Colorectal Cancer

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Bioactive constituents, mechanisms of action, and potential applications of Lonicerae Japonicae Flos as a dietary natural product for promoting gut health and managing ulcerative colitis and colorectal cancer. ABSTRACT Lonicerae Japonicae Flos (LJF), a traditional Chinese herb with applications in both medicine and nutrition, has emerged as a promising
Xiaoyu Huang, Letian Zhang, Zenghui Shi, Ni Zhu, Yifei Liu, Yanhong Zhou   +5 more
wiley   +1 more source

Humoral immunity in cancer. [PDF]

Signal Transduct Target Ther
Leonard J, Duhamel M, Salzet M.
europepmc   +1 more source

3D ex vivo platform for high‐throughput immunotherapy screening in relapsed/refractory lymphoma patients

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Relapsed/refractory (R/R) B‐cell lymphomas (B‐NHL) remain incurable, with limited predictive biomarkers to guide immunotherapy. Preclinical platforms that faithfully preserve the immune context and the viability of patient samples are critically needed for relevant high‐throughput drug testing.
Fabien Gava, Paul Marcoux, Neus Serrat, Pauline Gravelle, Sonia Quertinmont, Marie Tosolini, Carla Faria, Juan G. Valero, Christina Schniederjohann, Cathy Quelen, Fanny Bouquet, Catia Fonseca, Sylvia Herter, Laura C. Deak, Ron McCord, Eugene Chiang, Peter‐Martin Bruch, Loïc Ysebaert, Patricia Pérez‐Galán, Camille Laurent, Christine Bezombes   +20 more
wiley   +1 more source

Transcriptomic analysis of a phase 1 trial for intraperitoneal monocytes plus IFNs in ovarian cancer reveals support and recruitment of cell-mediated immunity. [PDF]

J Immunother Cancer
Ning F, San Andres-Montalvan E, Meyer TJ, Kaczanowska S, Kaplan R, Annunziata CM.   +5 more
europepmc   +1 more source

Systemic Inflammation and Subclinical Hepatic Synthetic Dysfunction Following Doxorubicin‐Cyclophosphamide Chemotherapy in Ethiopian Women With Breast Cancer: A Prospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Doxorubicin‐cyclophosphamide (AC) chemotherapy induces hepatotoxicity through oxidative stress and inflammatory pathway activation, but prospective African data are lacking and conventional liver tests may miss subclinical injury.
Tamrat Nida, Abdisa Tufa Bedada
wiley   +1 more source

CXCR3 signaling promotes Delta One T cell recruitment and antitumor efficacy in colorectal cancer. [PDF]

J Immunother Cancer
Carreira M, Barros L, Cruz RM, Ferreira C, Costa C, Ferreira CM, Mensurado S, Silva-Santos B, Blanco-Domínguez R.   +8 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, Volume 3, Issue 3, September 2026.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

How experimental models have unlocked hidden mechanisms of hypersensitivity pneumonitis. [PDF]

Eur Respir Rev
Cabrera S, Pardo A, Selman M.
europepmc   +1 more source