Results 171 to 180 of about 15,411,883 (261)

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K   +5 more
wiley   +1 more source

Immune Checkpoint Inhibitors in Cancer Therapy: Clinical Landscape, Resistance Mechanisms, and Therapeutic Innovations

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
The up‐to‐date clinical progress of immune checkpoint inhibitor (ICI) therapy in solid tumors, specifically the combinational regimens between ICIs and other treatment strategies, the mechanisms underlying primary and acquired resistance, and mechanism‐matched strategies to improve clinical outcomes are synthesized in this review.
Qiongyu Zhang, Zhi Qin, Caijuan Guo
wiley   +1 more source

IgG Subclass (IgG1‐4) and IgA Autoantibody Profiles Against Muscle‐Specific Kinase in a Greek Cohort

open access: yesMuscle &Nerve, Volume 74, Issue S1, Page S132-S141, September 2026.
ABSTRACT Introduction/Aims Muscle‐specific kinase myasthenia gravis (MuSK‐MG) is an autoimmune neuromuscular disorder predominantly mediated by IgG4 autoantibodies disrupting MuSK signaling. The contribution of other isotypes remains incompletely defined. We characterized the serological profile of a Greek cohort of MuSK‐MG patients.
Sofia‐Natsοuko Gkotzamani   +22 more
wiley   +1 more source

Molecular Mechanisms and Therapeutic Applications of Extracellular Vesicles in Remodeling of the Skin Cancer Niche

open access: yesNano Select, Volume 7, Issue 9, September 2026.
Extracellular vesicles at the nexus of skin cancer progression and precision therapy. EVs orchestrate tumor microenvironment remodeling through cargo‐mediated intercellular communication, immune modulation, angiogenesis, and extracellular matrix reorganization, while also emerging as next‐generation platforms for targeted drug delivery, biomarker ...
Megha Kotian   +7 more
wiley   +1 more source

Integration of NanoMIPs With Gold‐Patterned Plasmonic Surfaces as Synthetic Protein A

open access: yesSmall Science, Volume 6, Issue 9, September 2026.
Epitope‐imprinted nanoMIPs are combined with plasmonic metal‐enhanced fluorescence to create a synthetic protein A‐like sensing platform for human IgG. The approach enables oriented antibody recognition with high sensitivity and selectivity, providing a robust route toward miniaturised and multiplexed diagnostic devices. In modern bioanalytical sensing,
Fabiana Grillo   +12 more
wiley   +1 more source

Immune imbalance in rheumatoid arthritis: insights from γδ T cell receptor phenotyping. [PDF]

open access: yesHum Cell
Biały S   +4 more
europepmc   +1 more source

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