Receptors, antigen, t-cell, gamma-delta

Annual Review of Immunology, 1991
T cells bearing specific gamma delta TCR are the major lymphoid population in certain epithelial tissues. There are striking differences between these and peripheral T cells. The epithelial gamma delta T cells exhibit highly restricted V gene use, preferential pairing of TCR chains, and lack of diversity at the junctions creating populations of cells ...
J P, Allison, W L, Havran
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Human T lymphocytes expressing gamma/delta T cell antigen receptor.

Clinical immunology and immunopathology, 1989
The majority of mature T lymphocytes express CD3-associated antigen receptor molecules (TCR) formed by alpha and beta chains. Recently, a minor subset has been identified that expresses a different CD3-associated heterodimer composed of gamma and delta chains. The TCR gamma/delta+ cell subset differs from conventional T cells for a number of phenotypic
MORETTA, ALESSANDRO +8 more
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Cytotoxicity of Human Hepatic Intrasinusoidal Gamma/Delta T Cells Depends on Phospho-antigen and NK Receptor Signaling

Anticancer Research, 2022
We previously showed that human hepatic intrasinusoidal (HI) natural killer (NK) T cells selectively eliminate hepatocellular carcinoma (HCC) cell lines. In this study, we investigated the underlying mechanisms on how HI γδ T cells, expanded with zoledronate, exhibit a superior cytotoxic effect on HI NK-resistant Huh7 HCC cells.γδ T cells were obtained
Yoorha, Kang +10 more
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3. good health
t-lymphocytes
humans

animals
receptors, antigen, t-cell
mice

antibodies, monoclonal
lymphocyte activation
cytotoxicity, immunologic