Results 161 to 170 of about 27,293 (229)

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

open access: yesSmall, Volume 22, Issue 36, 26 June 2026.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu   +5 more
wiley   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

open access: yesVIEW, Volume 7, Issue 3, June 2026.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai   +11 more
wiley   +1 more source

Immunological Biomarkers in Glioblastoma: Targeting T and NK Cells for Enhanced Diagnosis and Prognosis. [PDF]

open access: yesBiologics
Akbari AM   +6 more
europepmc   +1 more source

Loss of SMARCAD1 Mitigates Tauopathy

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Using genetics approaches in a C. elegans transgenic model of tauopathy, we uncover a role for the homolog of human SMARCAD1, a regulator of chromatin dynamics. ABSTRACT Tauopathies are neurodegenerative diseases characterized by the accumulation of misfolded tau protein and include Alzheimer's disease (AD) and related dementia disorders.
Vaishnavi S. Jadhav   +7 more
wiley   +1 more source

Engineering gamma delta T cells limits tonic signaling associated with chimeric antigen receptors

open access: yes, 2019
Fisher, J   +11 more
openaire   +1 more source

Tumor infiltrating lymphocytes against solid tumors: current trends & perspectives. [PDF]

open access: yesPeerJ
Liew ZM   +8 more
europepmc   +1 more source

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