Results 161 to 170 of about 15,411,883 (261)

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

open access: yesJournal of Applied Toxicology, Volume 46, Issue 9, Page 3274-3287, September 2026.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer   +4 more
wiley   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

open access: yesLegume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid   +4 more
wiley   +1 more source

Regulatory T cells sabotage anti-tumor γδ T cells by creating IL-2-deficient environments. [PDF]

open access: yesJ Exp Med
Blanco-Domínguez R   +10 more
europepmc   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang   +10 more
wiley   +1 more source

Temporal single-cell transcriptional dynamics of murine pancreatic islet remodeling during hyperglycaemia progression. [PDF]

open access: yesMol Metab
Singh S   +10 more
europepmc   +1 more source

Ursodeoxycholic Acid Reduces Angiotensin‐Converting Enzyme 2 Activity and Suppresses Cytokine Storm Syndrome in Patients With Coronavirus Disease 2019

open access: yesMedComm, Volume 7, Issue 9, September 2026.
SARS‐CoV‐2 infection causes COVID‐19 and stimulates immune cells, such as dendritic cells, monocytes, and macrophages, to increase levels of many cytokines. Ursodeoxycholic acid (UDCA) inhibits farnesoid X receptor (FXR), resulting in a decrease in the activity of angiotensin‐converting enzyme 2 (ACE2), the main receptor on the membrane for SARS‐CoV‐2.
Zhaowei Tong   +8 more
wiley   +1 more source

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