Results 81 to 90 of about 44,035 (314)

The contribution of the genomes of a termite and a locust to our understanding of insect neuropeptides and neurohormones

Frontiers in Physiology, 2014
The genomes of the migratory locust Locusta migratoria and the termite Zootermopsis nevadensis were mined for genes encoding neuropeptides, neurohormones and their G-protein coupled receptors (GPCRs).
Jan Adrianus Veenstra
doaj   +1 more source

Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

The Journal of Headache and Pain, 2022
Background The clinical use of calcitonin gene-related peptide receptor (CGRP-R) antagonists and monoclonal antibodies against CGRP and CGRP-R has offered new treatment possibilities for migraine patients.
Sanne Hage La Cour, Kiki Juhler, Lisette J. A. Kogelman, Jes Olesen, Dan Arne Klærke, David Møbjerg Kristensen, Inger Jansen-Olesen   +6 more
doaj   +1 more source

Gene Transfer of Calcitonin Gene-Related Peptide Inhibits Macrophages and Inflammatory Mediators in Vein Graft Disease [PDF]

, 2008
Vein graft disease is a chronic inflammatory disease and limits the late results of coronary revascularization. Calcitonin gene-related peptide (CGRP) inhibits macrophages infiltrated and inflammatory mediators, we hypothesized that transfected CGRP gene
Hongsui Wu, Huanxin Yang, Jian Su, Jian Zhuang, Jianguang Chen, Shiliang Chen, Xiaoning Zhang, Yuhui Zheng, Zhihong Chen   +8 more
core   +1 more source

DINeR: Database for Insect Neuropeptide Research [PDF]

, 2017
Neuropeptides are responsible for regulating a variety of functions, including development, metabolism, water and ion homeostasis, and as neuromodulators in circuits of the central nervous system.
Davies, Shireen-Anne, Dow, Julian, Nässel, Dick R., Pandit, Aniruddha A., Yeoh, Joseph G.C., Zandawala, Meet   +5 more
core   +1 more source

Calcitonin Receptors on Cultured Human Lymphocytes

Journal of Biological Chemistry, 1974
SUMMARY Established human lymphoid cell lines bound calcitonin with high affinity. Calcitonin binding was detectable on both B cell and T cell lines derived from patients with a spectrum of lymphoproliferative disorders. These cell lines had marked differences in binding capacity per cell even when adjusted for differences in surface area.
S J, Marx, G D, Aurbach, J R, Gavin, D W, Buell   +3 more
openaire   +2 more sources

Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro‐Vascularized Bone Regeneration

Advanced Science, EarlyView.
This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su, Haomin Wang, Weixi Liu, Kangming Chen, Yiyang Min, Jinbo Zhu, Xueyang Li, Anning Su, Hao Yang, Lei Yang, Yun Ji, Yuxin Zhang, Jisi Zheng, Chi Yang, Chuanglong He, Tao Li, Shuo Chen, Tao Wu, Xiaodong Chen   +18 more
wiley   +1 more source

Functional Analysis and Tissue-Specific Expression of Calcitonin and CGRP with RAMP-Modulated Receptors CTR and CLR in Chickens

Animals
Calcitonin (CT) and calcitonin gene-related peptide (CGRP) are critical regulators of calcium balance and have extensive implications for vertebrate physiological processes.
Tianjiao Huang, Jiancheng Su, Xinglong Wang, Ningkun Shi, Xiao Zhang, Jiliang He, Juan Li, Jiannan Zhang, Yajun Wang   +8 more
doaj   +1 more source

Evolution of secretin family GPCR members in the metazoa

BMC Evolutionary Biology, 2006
Background Comparative approaches using protostome and deuterostome data have greatly contributed to understanding gene function and organismal complexity.
Clark Melody S, Vieira Florbela A, Pinto Vanda C, Cardoso João CR, Power Deborah M   +4 more
doaj   +1 more source

Specificity of Porcine Calcitonin Receptor and Calcitonin Receptor-like Receptor in the Presence of Receptor-Activity-Modifying Proteins

Hypertension Research, 2003
Adrenomedullin (AM), calcitonin gene-related peptide (CGRP), amylin (AMY) and calcitonin (CT) are members of the CGRP/CT superfamily of peptides. Among them, AM and CGRP are reported to share a core receptor, the calcitonin receptor-like receptor (CRLR), and the specificity of the CRLR is determined by the expression levels of receptor-activity ...
Katsuro, Kikumoto, Takeshi, Katafuchi, Naoto, Minamino   +2 more
openaire   +3 more sources

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, EarlyView.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source