Results 91 to 100 of about 33,788 (287)

PACAP and its role in primary headaches

The Journal of Headache and Pain, 2018
Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide implicated in a wide range of functions, such as nociception and in primary headaches.
Lars Edvinsson, János Tajti, Levente Szalárdy, László Vécsei   +3 more
doaj   +1 more source

PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma. [PDF]

, 2018
The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large majority of migraine patients has resulted in considerable excitement in ...
Akerman, Simon, Baca, Serapio M, Waschek, James A   +2 more
core   +2 more sources

Can trigeminal sensations impact saltiness perception? A mini‐review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan, Nicoletta Faraone, Matthew B McSweeney   +2 more
wiley   +1 more source

Nasal Air‐Jet Sensitivity Differentiates Empty Nose Syndrome and Turbinate Reduction Patients: A Pilot Study

The Laryngoscope, EarlyView.
This prospective pilot study aims to compare nasal mucosal sensitivity to air‐jet stimuli between ENS patients and patients who underwent septoplasty/turbinate reduction (septo‐turb) surgery, but without ENS symptoms. The ENS group had a significantly higher (less sensitive) threshold than the septo‐turb group for the septum opposing the center of the ...
Kanghyun Kim, Ahmad Odeh, Jack Harness, Nidhi Jha, Veronica Formanek, Joseph Lee, Bradley Otto, Kathleen Kelly, Kai Zhao   +8 more
wiley   +1 more source

Neuronal pathways in tendon healing and tendinopathy : update [PDF]

, 2016
The regulatory mechanisms involved in tendon homeostasis and repair are not fully understood. Accumulating data, however, demonstrate that the nervous system, in addition to afferent (sensory) functions, through efferent neuronal pathways plays an active
Ackermann, Paul, Carr, Andrew J, Dean, Benjamin J F, Franklin, Sarah L, Hart, David A, Salo, Paul T   +5 more
core   +1 more source

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

Current and prospective pharmacological targets in relation to antimigraine action [PDF]

, 2008
Migraine is a recurrent incapacitating neurovascular disorder characterized by unilateral and throbbing headaches associated with photophobia, phonophobia, nausea, and vomiting. Current specific drugs used in the acute treatment of migraine interact with
A Bergerot, A Buchwalder, A Carlsson, A Carlsson, A Hughes, A MaassenVanDenBrink, A MaassenVanDenBrink, A May, A May, A May, A Pindon, A Rouleau, A Srikiatkhachorn, A Sudilovsky, A Tanoue, A Wackenfors, AC Honey, AD Bennett, AD Medhurst, AD Michel, AE Luebke, AH Bom, AH Calhoun, AJ Kaumann, AL Magos, AM Aloisi, AM Carruthers, AM Lands, AM Maagdenberg van den, Antoinette MaassenVanDenBrink, AP Ford, AP Silva, B Forssman, B Gómez-Mancilla, B Pouzet, B Schaerlinger, B Weiss, BB Fredholm, BB Hoffman, BJ Francken, BK Kobilka, BK Rasmussen, BW Somerville, BW Somerville, C Hofmann, C Hohoff, C Lampl, C Tzourio, CA Salvatore, Carlos M. Villalón, CG Dahlöf, CM Villalón, CM Villalón, CM Villalón, CM Villalón, CN Sang, CY Yu, D Centurión, D Hoyer, D Hoyer, D Sarsero, DA Curran, David Centurión, DB Bylund, DB Bylund, DB Bylund, DB Bylund, DB Bylund, DD Mitsikostas, DD Mitsikostas, DE Dluzen, DJ Goldstein, DJ Goldstein, DJ Goldstein, DL Jackson, DM Pérez, DR Poyner, DR Thomas, DR Thomas, DS Millson, DW Dodick, E Del Bene, E Enmark, E Fabbretti, E Fusayasu, E Tronvik, EA Barnard, EA MacGregor, EA MacGregor, EA MacGregor, EA MacGregor, EM Cassidy, EW Willems, EW Willems, EW Willems, EW Willems, F Facchinetti, F Facchinetti, F Marceau, F Martínez, FG Freitag, FM Cutrer, FM Cutrer, FM Cutrer, G Attali, G Burnstock, G D’Andrea, G Trapani Di, GA Lambert, GA Michelotti, GL Stiles, GM Terwindt, GW Price, GW Smith, H Doods, H Heyck, H Kaube, H Kowa, H Schrader, HC Diener, HM Vargas, HO Kalkman, HS Blaxall, I Jansen-Olesen, I Mody, IH Page, IT Forbes, J Galitzky, J Honkaniemi, J Olesen, J Olesen, JA Charles, JA Terrón, JB Becker, JC Jen, JC Shih, JD Carroll, JD Classey, JE Palmer, JJ Fernández-Ruíz, JL Brandes, JM Brundege, JM Cruickshank, JM Orshal, JP Dreier, JP Hieble, JP Hieble, JR Arch, JR Clements, JR Docherty, JR Fozard, JW Lomasney, JW Regan, K Kapoor, K Schmuck, K Zimmermann, KA Krobert, KA Petersen, KA Petersen, Kayi Y. Chan, KI Roon, KJ Powell, KL Hoskin, KMA Welch, KP Lesch, KR Oliver, KW Johnson, L Edvinsson, L Edvinsson, L Hein, LA Phebus, LE Limbird, LH Lassen, LH Lassen, LH Lassen, LJ Smith, LL Ven van de, LM McLatchie, M Anthony, M Anthony, M Boccuni, M Cyr, M Farkkila, M Gasparo De, M Hasselblatt, M Iovino, M Kallela, M Mochi, M Oshita, M Peeters, M Quartu, M Spedding, M Yanagisawa, MA Moskowitz, MA Moskowitz, MD Ferrari, MD Ferrari, ME Bigal, ME Erdal, ME Moreau, MG Garry, MG Hanna, MJ Kelly, ML Hernández, MM Rapport, MT Piascik, NG Bowery, NJ Colson, NJ Colson, NJ Giffin, NM Barnes, NM Ramadan, NM Ramadan, NM Ramadan, NT Mathew, O Blin, P Barbanti, P Barbanti, P Geppetti, P Kastner, P Roffey, P Sarchielli, P Sarchielli, P Tfelt-Hansen, P Tfelt-Hansen, P Vries De, P Vries De, PD Drummond, PD Drummond, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PJ Goadsby, PL Durham, PP Lakhlani, PR Saxena, PR Saxena, PR Saxena, PR Saxena, Pramod R. Saxena, PT Hurley, QP Ma, R Burstein, R Cerbo, R Hering-Hanit, R Lodi, R Quirion, R Rabkin, R Uddman, R Würz, RA Bond, RA Ophoff, RB Lipton, RB McCall, RE Widdop, RJ Storer, RJ Storer, RJ Storer, RL Weinshank, RO Millán-Guerrero, RO Millán-Guerrero, RP Ahlquist, RW Kimball, RWM Broek van den, S Akerman, S Akerman, S Akerman, S Akerman, S Akerman, S Cotecchia, S Ghelardoni, S Gupta, S Gupta, S Gupta, S Maude, S Mehrotra, S Mehrotra, S Nag, S Paterna, S Shepheard, S Stellar, Saurabh Gupta, SD Brain, SD Silberstein, SD Silberstein, SD Silberstein, SG Hamilton, SJ Hill, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Peroutka, SJ Tallaksen-Greene, SJ Tepper, SM Lanier, SP Alexander, SP Cook, SP Cook, ST Lee, Suneet Mehrotra, T Attina, T Ishida, T Ishida, T Matsubara, T Takenaka, TJ Murphy, TM Buchanan, TW Ho, U Arulmani, U Arulmani, U Arulmani, V Erspamer, V Erspamer, V Johannsson, V Limmroth, V Shaygannejad, V Simonneaux, VT Martin, W Chai, WF Stewart, WI Bender, WL Hasler, WM Herrmann, WS Lee, Y Dumont, Y Sahara, Y Zhang, YT Lau, Z Cohen, Z Zhang   +335 more
core   +5 more sources

Relief of pain associated with spasticity in adult patients after treatment with onabotulinumtoxinA: Post hoc observational results from the ASPIRE study

PM&R, EarlyView.
Abstract Background Pain is often observed in patients with spasticity, but little is known about the relationship between pain and spasticity and the effectiveness of treating pain with botulinum toxins in these patients. Objective To explore onabotulinumtoxinA (onabotA) use and pain relief in patients with spasticity with pain at baseline.
Jörg Wissel, Cassandra List, Marc Schwartz, Mariana Nelson, Tiziana Musacchio, Esther Duarte   +5 more
wiley   +1 more source

Improved cardiac performance with human calcitonin gene related peptide in patients with congestive heart failure [PDF]

, 2017
Study objective - The aim of the study was to assess the cardiovascular effects of human calcitonin gene related peptide (CGRP) in patients with congestive heart failure.
Agnusdei, D., Fischer, J A., Gennari, C., Nami, R.   +3 more
core  

G Protein–Coupled Receptors in Olfactory Signaling and Related Disorders: Mechanisms and Therapeutic Implications

Sensory Neuroscience, EarlyView.
This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo, Hongjie Du, Fanyu Yuan, Yuhan Dong, Fangyuan Zhu, Jian Liu, Chengzhilin Li, Xu Guo, Zhaoze Yang, Wenwen Qi, Ming Xia, Chengcheng Liu   +11 more
wiley   +1 more source