Results 61 to 70 of about 12,370,091 (268)
Evolution of secretin family GPCR members in the metazoa
BMC Evolutionary Biology, 2006 Background Comparative approaches using protostome and deuterostome data have greatly contributed to understanding gene function and organismal complexity.
Clark Melody S +4 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Migraine and epilepsy frequently coexist, but evidence on the safety of calcitonin gene‐related peptide (CGRP)‐targeting therapies in people with epilepsy is lacking. We evaluated long‐term migraine and epilepsy outcomes in a real‐world multicenter retrospective cohort of adults with comorbid migraine and epilepsy treated with anti‐CGRP ...
Marina Romozzi +13 more
wiley +1 more source
Calcitonin Gene-Related Peptide Receptor Antagonists for Migraine Prophylaxis [PDF]
Hospital Pharmacy, 2017 Migraine is a common disorder affecting 12% of the U.S. population. Prophylaxis is recommended for patients who experience frequent migraines. Because current drugs used for prophylaxis are not 100% effective and cause adverse effects that affect compliance, new strategies have been studied to prevent headaches. One new pharmacologic strategy is to use
openaire +2 more sources
Sex differences in expression of CGRP family of receptors and ligands in the rat trigeminal system
The Journal of Headache and PainBackground Calcitonin gene-related peptide (CGRP) is part of the calcitonin peptide family, which includes calcitonin (CT), amylin (AMY), and adrenomedullin (ADM). CGRP and its receptor are highly present in the trigeminovascular system (TVS).
Aida Maddahi +2 more
doaj +1 more source
Botulinum Toxin for First Bite Syndrome: A Symptom‐Guided “Follow‐The‐Pain” Injection Strategy
Head &Neck, EarlyView.ABSTRACT Background To evaluate botulinum toxin type A (BoNT‐A) for First Bite Syndrome (FBS) and assess a symptom‐guided “Follow‐the‐Pain” (FTP) injection strategy in patients with incomplete response to standard treatment. Methods Consecutive patients with postoperative FBS were treated with ultrasound‐guided intraparotid BoNT‐A injection.
Rosario Marchese‐Ragona +5 more
wiley +1 more source
International Journal of Molecular SciencesColorectal cancer is one of the most widespread types of cancer that still causes many deaths worldwide. The development of new diagnostic and prognostic markers, as well as new therapeutic methods, is necessary. The calcitonin gene-related peptide (CGRP) neuropeptide alongside its receptor calcitonin receptor-like receptor (CRLR) could represent ...
Robert-Emmanuel Șerban +12 more
openaire +2 more sources
Tissue Clearing for Lymph Nodes: 3D Mapping of Nerves and the Immune Microenvironment
iNew Medicine, EarlyView.ABSTRACT Lymph nodes (LNs) are central hubs of adaptive immunity and key relay sites for metastatic tumour cells. However, conventional two‐dimensional histology samples only a small fraction of each node, potentially missing micrometastases and multifocal involvement while obscuring long‐range spatial relationships among tumour deposits, immune ...
Guang‐Hong Su +7 more
wiley +1 more source
Intermedin Is a Calcitonin/Calcitonin Gene-related Peptide Family Peptide Acting through the Calcitonin Receptor-like Receptor/Receptor Activity-modifying Protein Receptor Complexes [PDF]
Journal of Biological Chemistry, 2004 Calcitonin, calcitonin gene-related peptide (CGRP), adrenomedullin (ADM), and amylin belong to a unique group of peptide hormones important for homeostasis in diverse tissues. Calcitonin is essential for calcium balance, whereas CGRP and ADM are important for neurotransmission and cardiovascular and respiratory regulation.
Jaesook, Roh +4 more
openaire +2 more sources
Interdisciplinary Medicine, EarlyView.This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang +8 more
wiley +1 more source
Inducible Laryngeal Obstruction in Hypermobile Patients
The Laryngoscope, EarlyView.Patients with hypermobile Ehlers‐Danlos syndrome (hEDS) or hypermobility spectrum disorders (HSD) who screened positive for inducible laryngeal obstruction (ILO) reported significantly greater voice, cough, swallowing, gastrointestinal, and mast cell‐related symptoms than those without ILO. Chronic cough, dysphagia, and elevated mast cell symptom score
Stacey M. Menton +10 more
wiley +1 more source