Results 61 to 70 of about 18,546 (234)

Sex differences in expression of CGRP family of receptors and ligands in the rat trigeminal system

The Journal of Headache and Pain
Background Calcitonin gene-related peptide (CGRP) is part of the calcitonin peptide family, which includes calcitonin (CT), amylin (AMY), and adrenomedullin (ADM). CGRP and its receptor are highly present in the trigeminovascular system (TVS).
Aida Maddahi, Jacob C. A. Edvinsson, Lars Edvinsson   +2 more
doaj   +1 more source

Is neurogenic inflammation involved in tendinopathy? A systematic review

BMJ Open Sport & Exercise Medicine, 2023
Neurogenic pain and inflammation have been hypothesised to play an important role in tendinopathy. This systematic review aimed to present and assess the evidence on neurogenic inflammation in tendinopathy.
Neal L Millar, Dimitris Challoumas, George A C Murrell, Shimon Vinay Zedeck Wasker, Wai Weng   +4 more
doaj   +1 more source

Pelvic venous disorders in women: Diagnosis and management for gynecologists

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni, Inbar Friedman, Jessica Smith, Brian Liu, Mary Melchior, Andrew D. Brown   +5 more
wiley   +1 more source

Can trigeminal sensations impact saltiness perception? A mini‐review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan, Nicoletta Faraone, Matthew B McSweeney   +2 more
wiley   +1 more source

“What Medical Management Should Be First Line for Bladder Storage Symptoms in NLUTD”—Pro Botox

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives Neurogenic lower urinary tract dysfunction (NLUTD) severely impairs patient quality of life (QoL). While oral medications are often first‐line treatments, their high failure rates and side effects limit their effectiveness. Thus, we argue for the use of intravesical botulinum toxin A (BoNT‐A) injections as a first‐line alternative ...
Vada Furlan, Alyssa Kobayashi, Zhina Sadeghi   +2 more
wiley   +1 more source

Insulin sensitizes neural and vascular TRPV1 receptors in the trigeminovascular system

The Journal of Headache and Pain, 2022
Background Clinical observations suggest that hyperinsulinemia and insulin resistance can be associated with migraine headache. In the present study we examined the effect of insulin on transient receptor potential vanilloid 1 (TRPV1) receptor-dependent ...
Judit Rosta, Máté Tóth, Nadine Friedrich, Péter Sántha, Gábor Jancsó, Mária Dux   +5 more
doaj   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Functional Analysis and Tissue-Specific Expression of Calcitonin and CGRP with RAMP-Modulated Receptors CTR and CLR in Chickens

Animals
Calcitonin (CT) and calcitonin gene-related peptide (CGRP) are critical regulators of calcium balance and have extensive implications for vertebrate physiological processes.
Tianjiao Huang, Jiancheng Su, Xinglong Wang, Ningkun Shi, Xiao Zhang, Jiliang He, Juan Li, Jiannan Zhang, Yajun Wang   +8 more
doaj   +1 more source

Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

The Journal of Headache and Pain, 2022
Background The clinical use of calcitonin gene-related peptide receptor (CGRP-R) antagonists and monoclonal antibodies against CGRP and CGRP-R has offered new treatment possibilities for migraine patients.
Sanne Hage La Cour, Kiki Juhler, Lisette J. A. Kogelman, Jes Olesen, Dan Arne Klærke, David Møbjerg Kristensen, Inger Jansen-Olesen   +6 more
doaj   +1 more source

Triptans and Calcitonin gene-related peptide (CGRP) receptor antagonists

Rinsho Shinkeigaku, 2012
While triptans, the 5-HT1B/1D agonists, are effective and generally well-tolerated in many patients up to one-third of migraine patients either may not respond well to triptans, may not tolerate their side effects, or may have contraindications that preclude their use.
openaire   +3 more sources