Results 21 to 30 of about 9,580 (229)

[The role of calcium, calcitriol and their receptors in parathyroid regulation].

Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009
The mechanism of regulation of Parathyroid hormone (PTH) is complex, and diverse factors are involved: the fundamental ones are calcium, calcitriol and phosphorus. Calcium and calcitriol's mechanism of action takes place through its specific receptors, the calcium-sensing receptor (CaR) and the Vitamin D Receptor (VDR). These two factors have an effect
N, Carrillo-López, J L, Fernández-Martín, J B, Cannata-Andía   +2 more
openaire   +2 more sources

Simultaneous changes in the calcium-sensing receptor and the vitamin D receptor under the influence of calcium and calcitriol [PDF]

Nephrology Dialysis Transplantation, 2008
The regulatory mechanisms of parathyroid hormone (PTH) synthesis are complex, involving calcium, calcitriol, the calcium-sensing receptor (CaR) and the vitamin D receptor (VDR). In this study, the effects of calcium and calcitriol on the simultaneous expression of CaR and VDR mRNA and protein levels were assessed in parathyroid glands cultured in vitro.
Natalia, Carrillo-López, Daniel, Alvarez-Hernández, Ignacio, González-Suárez, Pablo, Román-García, Jose M, Valdivielso, José Luis, Fernández-Martín, Jorge B, Cannata-Andía   +6 more
openaire   +2 more sources

Inhibition of nuclear uptake of calcitriol receptor by uremic ultrafiltrate

Kidney International, 1994
The biological action of calcitriol is mediated through a hormone-receptor complex interacting with nuclear chromatin. Interaction of the calcitriol receptor (VDR) with VDR response elements produces bioactive proteins which carry out the physiological actions of calcitriol.
Patel, Sanjeevkumar R., Qiong Ke, Hui, Vanholder, Raymond, Hsu, Chen H.   +3 more
openaire   +2 more sources

Vitamin D, the Vitamin D Receptor, Calcitriol Analogues and Their Link with Ocular Diseases

Nutrients, 2022
The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents.
Miłosz Caban, Urszula Lewandowska
openaire   +2 more sources

Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D [PDF]

, 2015
The anticancer actions of vitamin D and its hormonally active form, calcitriol, have been extensively documented in clinical and preclinical studies. However, the mechanisms underlying these actions have not been completely elucidated.
Feldman, David, Diehn, Maximilian, Horst, Ronald L, Jeong, Youngtae, Feldman, Brian J, Williams, Jasmaine D, Martin, Shanique, Albertelli, Megan A, Krishnan, Aruna V, Swami, Srilatha   +9 more
core   +1 more source

Association between Polymorphism in Vitamin D Receptor Gene and Diabetic Retinopathy of Type 2 Diabetes in Korean Population [PDF]

Endocrinology and Metabolism, 2015
BackgroundType 2 diabetes is one of the most common diseases with devastating complications. However, genetic susceptibility of diabetic complications has not been clarified.
Yong Joo Hong, Eun Seok Kang, Myoung Jin Ji, Hyung Jin Choi, Taekeun Oh, Sung-Soo Koong, Hyun Jeong Jeon   +6 more
doaj   +1 more source

Association between serum vitamin d level and glaucoma in women

Acta Clinica Croatica, 2016
The aim of the study was to determine whether serum vitamin D level is lower in female patients with glaucoma as compared with control group. The mechanism by which vitamin D reduces intraocular pressure is not fully clarified. Almost all tissues possess
Željka Vuković Arar, Marijana Knežević Praveček, Blaženka Miškić, Zoran Vatavuk, Jadranka Vuković Rodriguez, Sandra Sekelj   +5 more
doaj   +1 more source

The Role of Vitamin D in Primary Biliary Cirrhosis: Possible Genetic and Cell Signaling Mechanisms

Gastroenterology Research and Practice, 2013
Primary biliary cirrhosis (PBC) is an immune-mediated chronic inflammatory disease of the liver of unknown etiology. Vitamin D deficiency is highly prevalent in patients with PBC, and many studies have demonstrated the significant effect of calcitriol on
Khanh vinh quốc Lương, Lan Thi Hoàng Nguyễn   +1 more
doaj   +1 more source

Vitamin D treatment of peripheral blood mononuclear cells modulated immune activation and reduced susceptibility to HIV-1 infection of CD4+ T lymphocytes.

PLoS ONE, 2019
IntroductionMucosal immune activation, in the context of sexual transmission of HIV-1 infection, is crucial, as the increased presence of activated T cells enhance susceptibility to infection.
Sandra M Gonzalez, Wbeimar Aguilar-Jimenez, Edison Trujillo-Gil, Wildeman Zapata, Ruey-Chyi Su, T Blake Ball, Maria T Rugeles, Maria T Rugeles   +7 more
doaj   +1 more source

Calcitriol and TO-901317 Interact in Human Prostate Cancer LNCaP Cells [PDF]

, 2008
Vitamin D receptor (VDR) and liver X receptor (LXR) are nuclear receptors, which regulate gene transcription upon binding of their specific ligands. VDR seems to play a role in the regulation of prostate cancer cell proliferation.
Pentti Tuohimaa, Jing-Huan Wang
core   +1 more source