Results 21 to 30 of about 549,113 (218)

Peptide receptor radionuclide therapy controls inappropriate calcitriol secretion in a pancreatic neuro-endocrine tumor: a case report

open access: yesBMC Gastroenterology, 2020
Background Hypercalcemia of malignancy is not uncommon in patients with advanced stage cancer. In rare cases the cause of the hypercalcemia is excessive production of calcitriol, the active form of vitamin D.
Maarten Haemels   +5 more
doaj   +1 more source

Physiological Basis for Using Vitamin D to Improve Health

open access: yesBiomedicines, 2023
Vitamin D is essential for life—its sufficiency improves metabolism, hormonal release, immune functions, and maintaining health. Vitamin D deficiency increases the vulnerability and severity of type 2 diabetes, metabolic syndrome, cancer, obesity, and ...
Sunil J. Wimalawansa
doaj   +1 more source

Characterisation of bovine leukocyte Ig-like receptors [PDF]

open access: yes, 2012
Leukocyte Immunoglobulin-like receptors (LILR) are innate immune receptors involved in regulating both innate and adaptive immune functions. LILR show more interspecies conservation than the closely related Killer Ig-like receptors, and homologues have ...
Jones, DC   +8 more
core   +4 more sources

Vitamin D and Glomerulonephritis

open access: yesMedicina, 2021
Vitamin D presents a plethora of different functions that go beyond its role in skeletal homeostasis. It is an efficient endocrine regulator of the Renin–Angiotensin–Aldosterone System (RAAS) and erythropoiesis, exerts immunomodulatory effects, reduces ...
Guido Gembillo   +4 more
doaj   +1 more source

Effect of calcitriol on bone turnover and osteocalcin in recent-onset type 1 diabetes [PDF]

open access: yes, 2013
Contains fulltext : 125353.pdf (Publisher’s version ) (Open Access)BACKGROUND: Vitamin D supplementation in childhood improves the achievement of peak bone mass.
Crinò, A   +57 more
core   +2 more sources

Simultaneous changes in the calcium-sensing receptor and the vitamin D receptor under the influence of calcium and calcitriol [PDF]

open access: yesNephrology Dialysis Transplantation, 2008
The regulatory mechanisms of parathyroid hormone (PTH) synthesis are complex, involving calcium, calcitriol, the calcium-sensing receptor (CaR) and the vitamin D receptor (VDR). In this study, the effects of calcium and calcitriol on the simultaneous expression of CaR and VDR mRNA and protein levels were assessed in parathyroid glands cultured in vitro.
Natalia, Carrillo-López   +6 more
openaire   +2 more sources

[The role of calcium, calcitriol and their receptors in parathyroid regulation].

open access: yesNefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2009
The mechanism of regulation of Parathyroid hormone (PTH) is complex, and diverse factors are involved: the fundamental ones are calcium, calcitriol and phosphorus. Calcium and calcitriol's mechanism of action takes place through its specific receptors, the calcium-sensing receptor (CaR) and the Vitamin D Receptor (VDR). These two factors have an effect
N, Carrillo-López   +2 more
openaire   +2 more sources

Effect of Schiff base formation on the function of the calcitriol receptor

open access: yesKidney International, 1996
The genomic action of calcitriol is mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of the target genes. We have shown that the interaction of VDRs with VDREs is inhibited by uremic toxins.
Patel, Sanjeevkumar R.   +2 more
openaire   +2 more sources

Decreased expression of vitamin D receptors in neointimal lesions following coronary artery angioplasty in atherosclerotic swine. [PDF]

open access: yesPLoS ONE, 2012
Inflammatory cytokines, such as TNF-α, play a key role in the pathogenesis of occlusive vascular diseases. Activation of vitamin D receptors (VDR) elicits both growth-inhibitory and anti-inflammatory effects. Here, we investigated the expression of TNF-α
Gaurav K Gupta   +4 more
doaj   +1 more source

Inhibition of nuclear uptake of calcitriol receptor by uremic ultrafiltrate

open access: yesKidney International, 1994
The biological action of calcitriol is mediated through a hormone-receptor complex interacting with nuclear chromatin. Interaction of the calcitriol receptor (VDR) with VDR response elements produces bioactive proteins which carry out the physiological actions of calcitriol.
Patel, Sanjeevkumar R.   +3 more
openaire   +2 more sources

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