Results 41 to 50 of about 549,113 (218)
Beneficial role of vitamin D in the prevention of certain respiratory diseases
Therapeutic Advances in Respiratory Disease, 2013 There is evidence of aberrations in the vitamin D–endocrine system in subjects with respiratory diseases. Vitamin D deficiency is highly prevalent in patients with respiratory diseases, and patients who receive vitamin D have significantly larger ...
Khanh vinh quốc Lương +1 more
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Association between Serum Vitamin D Levels and VDR BsmI Polymorphism in Temporomandibular Joint Dysfunction Patients (in the Iranian Population) [PDF]
Journal of DentistryBackground: Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders.Purpose: This study aimed to investigate the
Maryam Mostafavi +4 more
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Clinical Hypertension, 2023 The vitamin D receptor (VDR) gene serves as a good candidate gene for susceptibility to essential hypertension. The gene regulates the renin angiotensin system by influencing blood pressure regulation.
Richa Awasthi +2 more
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Effect of glucose on the function of the calcitriol receptor and vitamin D metabolism
Kidney International, 1997 The genomic action of calcitriol is mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of the target genes. It has been proposed that chemicals capable of Schiff base formation with the VDR potentially could alter the physiological function of VDR and calcitriol metabolism.
Patel, Sanjeevkumar R. +3 more
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, 2022 Calcitriol is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis.
Mowery, Myles +2 more
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Calcitriol imparts neuroprotection in vitro to midbrain dopaminergic neurons by upregulating GDNF expression [PDF]
, 2013 During development a tightly controlled signaling cascade dictates the differentiation, maturation and survival of developing neurons. Understanding this signaling mechanism is important for developing therapies for neurodegenerative illnesses.
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Regulation of calcitriol receptor and its mRNA in normal and renal failure rats
Kidney International, 1994 Homologous up-regulation of calcitriol receptor (VDR) by calcitriol is believed to be a transcriptional event. In this experiment, we studied the effect of calcitriol on VDR in normal and renal failure rats. The time course of the effect of calcitriol on VDR mRNA showed a biphasic change in VDR mRNA in response to calcitriol.
Patel, Sanjeevkumar R. +2 more
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The Effect of Active VitaminD on Treatment of Proteinuria in Patients with Diabetic Nephropathy without Vitamin D Deficiency [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016 Background: The renin-angiotensin system(RAS) has a major role in development of diabetic nephropathy and blocking of RAS by inhibitors and blocking of angiotesin receptors is standard treatment for preventing kidney disease and proteinuria.
Nader Saeedi +4 more
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Inhibition of calcitriol receptor binding to vitamin D response elements by uremic toxins. [PDF]
Journal of Clinical Investigation, 1995 The genomic action of calcitriol (1,25-dihydroxy-vitamin D3) is mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs). Although renal failure is associated with resistance to the action of calcitriol, the mechanism of this resistance is not well understood.
S R, Patel +4 more
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Putative helices 3 and 5 of the human vitamin D3 receptor are important for the binding of calcitriol [PDF]
FEBS Letters, 1998 We have introduced eleven point mutations into the human vitamin D receptor by site‐directed mutagenesis in order to identify some of the amino acid residues that are important for ligand binding. The amino acid residues Ser225, His229, Asp232, Val234, Ser235, Tyr236, Ser237, Lys240, Ile242, Lys246 (helix 3), and Ser275 (helix 5) of the human vitamin D
Väisänen, Sami +2 more
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