Results 51 to 60 of about 549,113 (218)

Inhibition of Mouse Breast Tumor-Initiating Cells by Calcitriol and Dietary Vitamin D [PDF]

, 2015
The anticancer actions of vitamin D and its hormonally active form, calcitriol, have been extensively documented in clinical and preclinical studies. However, the mechanisms underlying these actions have not been completely elucidated.
Feldman, David, Diehn, Maximilian, Horst, Ronald L, Jeong, Youngtae, Feldman, Brian J, Williams, Jasmaine D, Martin, Shanique, Albertelli, Megan A, Krishnan, Aruna V, Swami, Srilatha   +9 more
core   +1 more source

Old disease, new twist

Journal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

Postoperative Hypocalcemia Following Total Thyroidectomy Versus Completion Thyroidectomy

The Laryngoscope, EarlyView.
Completion thyroidectomy performed with at least a three‐month interval demonstrates superior parathyroid preservation compared to primary total thyroidectomy, as evidenced by significantly higher postoperative parathyroid hormone levels (51.90 ± 30.26 pg/mL vs. 30.90 ± 17.10 pg/mL, p = 0.006).
Mehmet Turan Cicek, Çiğdem Firat Koca, Mehmet Tan, Baransel Algan   +3 more
wiley   +1 more source

Renal functional, transcriptome, and methylome adaptations in pregnant Sprague Dawley and Brown Norway rats

PLoS ONE, 2022
Pregnancy induces maternal renal adaptations that include increased glomerular filtration rate and renal blood flow which can be compromised in obstetrical complications such as preeclampsia.
Zhong Chen, Charles Wang, Arlin Blood, Shannon Bragg, Eugenia Mata-Greenwood   +4 more
doaj   +2 more sources

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

The health benefits of vitamin D relevant for tuberculosis [PDF]

Journal of Medical Biochemistry, 2014
Vitamin D has an important role in numerous physiological functions. Vitamin D receptors are characterized by polymorphisms and presence in different tissues including a number of cells of the immune system.
Škodrić-Trifunović Vesna, Blanka Ana, Stjepanović Mihailo I., Ignjatović Svetlana, Mihailović-Vučinić Violeta, Šumarac Zorica, Buha Ivana, Ilić Katarina   +7 more
doaj  

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source

Efecto de dosis suprafisiológicas de calcitriol sobre la expresión proteica de células de músculo liso vascular

, 2017
Introducción: El calcitriol, fundamental para mantener la homeostasis del calcio y el fósforo en el organismo, puede perjudicar al sistema vascular a dosis elevadas, aumentando el riesgo de calcificación.
Tuñón LePoultel D, Quirós Caso C, Rodríguez I, Naves Díaz M, Carrillo López N, Cannata Andía JB   +5 more
core   +1 more source

Calcemic response to parathyroid hormone in renal failure: Role of calcitriol and the effect of parathyroidectomy [PDF]

, 1991
Calcemic response to parathyroid hormone in renal failure: Role of calcitriol and the effect of parathyroidectomy. Hyperparathyroidism due to renal failure begins in the early stages of renal insufficiency and is in part secondary to skeletal resistance ...
Rodriguez, Mariano, Llach, Francisco, Felsenfeld, Arnold J.   +2 more
core   +1 more source

Hypophosphataemia in adults: approach to diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Hypophosphataemia is a common electrolyte disorder which can have clinically significant consequences for bone, muscle, neurological and haematological function. Its causes range from transient transcellular shifts in hospitalised patients to chronic renal phosphate‐wasting disorders mediated by fibroblast growth factor 23 (FGF23).
Kajanan Parameshwaran, Mawson Wang, Kirtan Ganda   +2 more
wiley   +1 more source