Results 31 to 40 of about 9,580 (229)

Newly discovered activities for calcitriol (1,25-dihydroxyvitamin D 3 ): Implications for future pharmacological use [PDF]

, 1986
Recent studies have yielded new insights into the critical importance of adequate vitamin D 3 intake and metabolism. Investigations of the actions of 1,25-dihydroxyvitamin D 3 (calcitriol) on novel target tissues has revealed that this hormone has ...
Robert U. Simpson, Simpson, Robert U., Ronald Weishaar, Weishaar, Ronald E.   +3 more
core   +1 more source

Beneficial role of vitamin D in the prevention of certain respiratory diseases

Therapeutic Advances in Respiratory Disease, 2013
There is evidence of aberrations in the vitamin D–endocrine system in subjects with respiratory diseases. Vitamin D deficiency is highly prevalent in patients with respiratory diseases, and patients who receive vitamin D have significantly larger ...
Khanh vinh quốc Lương, Lan Thi Hoàng Nguyễn   +1 more
doaj   +1 more source

Fok I and Bsm I gene polymorphism of vitamin D receptor and essential hypertension: a mechanistic link

Clinical Hypertension, 2023
The vitamin D receptor (VDR) gene serves as a good candidate gene for susceptibility to essential hypertension. The gene regulates the renin angiotensin system by influencing blood pressure regulation.
Richa Awasthi, Priyanka Thapa Manger, Rajesh Kumar Khare   +2 more
doaj   +1 more source

Effect of glucose on the function of the calcitriol receptor and vitamin D metabolism

Kidney International, 1997
The genomic action of calcitriol is mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of the target genes. It has been proposed that chemicals capable of Schiff base formation with the VDR potentially could alter the physiological function of VDR and calcitriol metabolism.
Patel, Sanjeevkumar R., Xu, Yin, Koenig, Ronald J., Hsu, Chen H.   +3 more
openaire   +2 more sources

The Association between Vitamin D Receptor Expression and Prolonged Overall Survival in Breast Cancer. [PDF]

, 2011
Summary In this study, we analyzed vitamin D receptor (VDR) expression and survival in a breast cancer patient cohort of 82 breast cancer patients. Immunohistochemical analysis was possible in 91.5% of the patients (75/82). Staining was evaluated using
Lenhard, Miriam, Toth, Bettina, Jeschke, Udo, Klaus Friese, Weissenbacher, Tobias, Mayr, Doris, Julia Gallwas, Udo Jeschke, Nina Ditsch, Tobias Weissenbacher, Christian Dannecker, Gallwas, Julia, Dannecker, Christian, Miriam Lenhard, Ditsch, Nina, Friese, Klaus, Doris Mayr, Bettina Toth   +17 more
core   +1 more source

Effect of glyoxylate on the function of the calcitriol receptor and vitamin D metabolism

Kidney International, 1997
The biological action of calcitriol is mostly mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of target genes. These interactions produce special proteins that carry out the biological activities of calcitriol.
Patel, Sanjeevkumar R., Xu, Yin, Koenig, Ronald J., Hsu, Chen H.   +3 more
openaire   +2 more sources

Vitamin D receptor genotype influences parathyroid hormone and calcitriol levels in predialysis patients [PDF]

Kidney International, 1999
BsmI vitamin D receptor (VDR) gene polymorphism has been associated with the severity of hyperparathyroidism in patients on hemodialysis. The aim of this study was to analyze the influence of this polymorphism on parathyroid function and serum calcitriol levels in patients with different degrees of chronic renal failure (CRF) before dialysis.A total of
Marco, Maria Paz, Martínez, Isabel, Amoedo, Maria Luisa, Borràs, Mercè, Saracho, Ramón, Almirall, Jaume, Fibla, Joan, Fernández, Elvira   +7 more
openaire   +2 more sources

Regulation of calcitriol receptor and its mRNA in normal and renal failure rats

Kidney International, 1994
Homologous up-regulation of calcitriol receptor (VDR) by calcitriol is believed to be a transcriptional event. In this experiment, we studied the effect of calcitriol on VDR in normal and renal failure rats. The time course of the effect of calcitriol on VDR mRNA showed a biphasic change in VDR mRNA in response to calcitriol.
Patel, Sanjeevkumar R., Ke, Hui Qiong, Hsu, Chen H.   +2 more
openaire   +2 more sources

The Effect of Active VitaminD on Treatment of Proteinuria in Patients with Diabetic Nephropathy without Vitamin D Deficiency [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016
Background: The renin-angiotensin system(RAS) has a major role in development of diabetic nephropathy and blocking of RAS by inhibitors and blocking of angiotesin receptors is standard treatment for preventing kidney disease and proteinuria.
Nader Saeedi, Mohammadreza Rezvanfar, Mehdi Hadidi, Farvah Asgharizadeh Mahani, Mojtaba Ahmadlou   +4 more
doaj  

Association between Serum Vitamin D Levels and VDR BsmI Polymorphism in Temporomandibular Joint Dysfunction Patients (in the Iranian Population) [PDF]

Journal of Dentistry
Background: Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders.Purpose: This study aimed to investigate the
Maryam Mostafavi, Fahimeh Rezazadeh, Mohammad Javad Fattahi, Fatemeh Tavakoli, Abbas Ghaderi   +4 more
doaj   +1 more source