Results 31 to 40 of about 549,113 (218)

Vitamin D, the Vitamin D Receptor, Calcitriol Analogues and Their Link with Ocular Diseases

open access: yesNutrients, 2022
The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents.
Miłosz Caban, Urszula Lewandowska
openaire   +2 more sources

Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1β and TNF-α

open access: yesJournal of Immunology Research, 2019
Triple-negative breast cancer (TNBC) is one of the most aggressive tumors, with poor prognosis and high metastatic capacity. The aggressive behavior may involve inflammatory processes characterized by deregulation of molecules related to the ...
Isela Martínez-Reza   +7 more
doaj   +1 more source

Association between serum vitamin d level and glaucoma in women

open access: yesActa Clinica Croatica, 2016
The aim of the study was to determine whether serum vitamin D level is lower in female patients with glaucoma as compared with control group. The mechanism by which vitamin D reduces intraocular pressure is not fully clarified. Almost all tissues possess
Željka Vuković Arar   +5 more
doaj   +1 more source

Serum Concentration of Vitamin D in Patients with Oral Lichen Planus

open access: yesActa Stomatologica Croatica, 2023
Objectives: The vitamin D receptor is involved in immunologically mediated diseases such as oral lichen planus. Some studies suggest an association between lower vitamin D concentrations and a higher risk of inflammatory conditions such as oral lichen ...
Ana Družijanić   +5 more
doaj   +1 more source

Association between Polymorphism in Vitamin D Receptor Gene and Diabetic Retinopathy of Type 2 Diabetes in Korean Population [PDF]

open access: yesEndocrinology and Metabolism, 2015
BackgroundType 2 diabetes is one of the most common diseases with devastating complications. However, genetic susceptibility of diabetic complications has not been clarified.
Yong Joo Hong   +6 more
doaj   +1 more source

Effect of glyoxylate on the function of the calcitriol receptor and vitamin D metabolism

open access: yesKidney International, 1997
The biological action of calcitriol is mostly mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of target genes. These interactions produce special proteins that carry out the biological activities of calcitriol.
Patel, Sanjeevkumar R.   +3 more
openaire   +2 more sources

The Role of Vitamin D in Primary Biliary Cirrhosis: Possible Genetic and Cell Signaling Mechanisms

open access: yesGastroenterology Research and Practice, 2013
Primary biliary cirrhosis (PBC) is an immune-mediated chronic inflammatory disease of the liver of unknown etiology. Vitamin D deficiency is highly prevalent in patients with PBC, and many studies have demonstrated the significant effect of calcitriol on
Khanh vinh quốc Lương   +1 more
doaj   +1 more source

Vitamin D treatment of peripheral blood mononuclear cells modulated immune activation and reduced susceptibility to HIV-1 infection of CD4+ T lymphocytes.

open access: yesPLoS ONE, 2019
IntroductionMucosal immune activation, in the context of sexual transmission of HIV-1 infection, is crucial, as the increased presence of activated T cells enhance susceptibility to infection.
Sandra M Gonzalez   +7 more
doaj   +1 more source

Coordinate regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells [PDF]

open access: yes, 1996
Coordinate regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells. High levels of PTH result in desensitization of target cells to further stimulation with PTH in vivo and in vitro.
Martin, Kevin J., González, Esther A.
core   +1 more source

Vitamin D receptor genotype influences parathyroid hormone and calcitriol levels in predialysis patients [PDF]

open access: yesKidney International, 1999
BsmI vitamin D receptor (VDR) gene polymorphism has been associated with the severity of hyperparathyroidism in patients on hemodialysis. The aim of this study was to analyze the influence of this polymorphism on parathyroid function and serum calcitriol levels in patients with different degrees of chronic renal failure (CRF) before dialysis.A total of
Marco, Maria Paz   +7 more
openaire   +2 more sources

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