Vitamin D, the Vitamin D Receptor, Calcitriol Analogues and Their Link with Ocular Diseases
The global prevalence of eye diseases continues to grow, bringing with it a reduction in the activity levels and quality of life of patients, and partial or complete blindness if left untreated. As such, there is considerable interest in identifying more effective therapeutic options and preventive agents.
Miłosz Caban, Urszula Lewandowska
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Triple-negative breast cancer (TNBC) is one of the most aggressive tumors, with poor prognosis and high metastatic capacity. The aggressive behavior may involve inflammatory processes characterized by deregulation of molecules related to the ...
Isela Martínez-Reza +7 more
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Association between serum vitamin d level and glaucoma in women
The aim of the study was to determine whether serum vitamin D level is lower in female patients with glaucoma as compared with control group. The mechanism by which vitamin D reduces intraocular pressure is not fully clarified. Almost all tissues possess
Željka Vuković Arar +5 more
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Serum Concentration of Vitamin D in Patients with Oral Lichen Planus
Objectives: The vitamin D receptor is involved in immunologically mediated diseases such as oral lichen planus. Some studies suggest an association between lower vitamin D concentrations and a higher risk of inflammatory conditions such as oral lichen ...
Ana Družijanić +5 more
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Association between Polymorphism in Vitamin D Receptor Gene and Diabetic Retinopathy of Type 2 Diabetes in Korean Population [PDF]
BackgroundType 2 diabetes is one of the most common diseases with devastating complications. However, genetic susceptibility of diabetic complications has not been clarified.
Yong Joo Hong +6 more
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Effect of glyoxylate on the function of the calcitriol receptor and vitamin D metabolism
The biological action of calcitriol is mostly mediated through the interaction of the calcitriol receptor (VDR) with vitamin D response elements (VDREs) of target genes. These interactions produce special proteins that carry out the biological activities of calcitriol.
Patel, Sanjeevkumar R. +3 more
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The Role of Vitamin D in Primary Biliary Cirrhosis: Possible Genetic and Cell Signaling Mechanisms
Primary biliary cirrhosis (PBC) is an immune-mediated chronic inflammatory disease of the liver of unknown etiology. Vitamin D deficiency is highly prevalent in patients with PBC, and many studies have demonstrated the significant effect of calcitriol on
Khanh vinh quốc Lương +1 more
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IntroductionMucosal immune activation, in the context of sexual transmission of HIV-1 infection, is crucial, as the increased presence of activated T cells enhance susceptibility to infection.
Sandra M Gonzalez +7 more
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Coordinate regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells [PDF]
Coordinate regulation of PTH/PTHrP receptors by PTH and calcitriol in UMR 106-01 osteoblast-like cells. High levels of PTH result in desensitization of target cells to further stimulation with PTH in vivo and in vitro.
Martin, Kevin J., González, Esther A.
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Vitamin D receptor genotype influences parathyroid hormone and calcitriol levels in predialysis patients [PDF]
BsmI vitamin D receptor (VDR) gene polymorphism has been associated with the severity of hyperparathyroidism in patients on hemodialysis. The aim of this study was to analyze the influence of this polymorphism on parathyroid function and serum calcitriol levels in patients with different degrees of chronic renal failure (CRF) before dialysis.A total of
Marco, Maria Paz +7 more
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