Results 151 to 160 of about 28,855 (210)

The Relationship Between (Endo)cannabinoids, the Microbiome and Melanoma

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
CB1 and CB2 receptors are widely distributed in both normal and cancerous cells. Cannabinoids have a positive impact on reducing tumor growth in mice. A positive relationship exists between CB2 receptors and survival in skin melanoma. However, there is a negative impact on non‐small cell lung cancer and colon cancer, whereas a higher association of CB1
Farideh A. Javid   +3 more
wiley   +1 more source

Chemogenetic Activation of G12 Signaling Thickens the Epidermis With Enhanced Barrier Function

open access: yesFASEB BioAdvances, Volume 8, Issue 8, August 2026.
In this study, we investigated the role of G12 signaling in the epidermis using a keratinocyte‐specific chemogenetic approach. Activation of G12 signaling promoted keratinocyte differentiation and enhanced epidermal barrier function by upregulating filaggrin, claudin‐1, and ceramide.
Nozomi Kamakura   +8 more
wiley   +1 more source

Transcriptomic comparison on the mechanism of action of four major constituent cannabinoids in hemp extract. [PDF]

open access: yesJ Cannabis Res
Gao X   +7 more
europepmc   +1 more source

Might modulation of the endocannabinoid system provide a potential dual therapeutic strategy for osteoporosis and depression?

open access: yes
General Psychiatry, Volume 39, Issue 4, August 2026.
Peng Wei   +6 more
wiley   +1 more source

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

open access: yesAddiction, Volume 121, Issue 8, Page 2019-2032, August 2026.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu   +3 more
wiley   +1 more source

The association between sleep disturbance and stimulant use: A cross‐lagged examination

open access: yesAddiction, Volume 121, Issue 8, Page 2116-2126, August 2026.
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian   +12 more
wiley   +1 more source

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