Results 161 to 170 of about 57,210 (209)

Cannabinoids, cannabinoid receptors and tinnitus

Hearing Research, 2016
One hypothesis suggests that tinnitus is a form of sensory epilepsy, arising partly from neuronal hyperactivity in auditory regions of the brain such as the cochlear nucleus and inferior colliculus. Although there is currently no effective drug treatment for tinnitus, anti-epileptic drugs are used in some cases as a potential treatment option. There is
Paul F, Smith, Yiwen, Zheng
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Cannabinoid receptors in atherosclerosis

Current Opinion in Lipidology, 2006
Recent findings suggesting that cannabinoid receptors are potential targets for the treatment of atherosclerosis are reviewed.Cannabinoids, such as Delta9-tetrahydrocannabinol, the major psychoactive compound of marijuana, their synthetic analogs and endogenous cannabinoid ligands, produce their biological effects by interacting with specific receptors.
Sabine, Steffens, Francois, Mach
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Cannabis and cannabinoid receptors

Fitoterapia, 2000
Cannabis and cannabinoids exert many of their biological functions through receptor-mediated mechanisms. Two types of cannabinoid receptors have been identified, namely CB(1) and CB(2), both coupled to a G protein. CB(1) receptors have been detected in the central nervous system (where they are responsible for the characteristic effects of Cannabis ...
E. Nocerino, M. Amato, IZZO, ANGELO ANTONIO   +2 more
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Cannabinoid receptors in the kidney

Current Opinion in Nephrology and Hypertension, 2016
The endocannabinoid system modulates cell signaling targets that are essential for energy homeostasis. Endocannabinoids bind to G protein-coupled receptors in the central nervous system and periphery, including the kidney. Modulation of cannabinoid receptor 1 (CB1) and CB2 activity in the kidney in diabetes and obesity has been identified as potential ...
Hryciw, Deanne H, McAinch, Andrew J
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Cannabinoid receptors and immunity

Immunology Today, 1998
Abstract Marijuana cannabinoids are both psychoactive and immunoactive. Here, we will review evidence that cannabinoids modulate immunity and that cannabinoid receptors and endogenous ligands are expressed in immune tissues. Clues will also be presented concerning the role of the cannabinoid system in immune regulation and the possible molecular ...
T W, Klein, C, Newton, H, Friedman
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Cannabinoid receptors and their ligands

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2002
There are at least two types of cannabinoid receptors, CB(1) and CB(2), both coupled to G proteins. CB(1) receptors exist primarily on central and peripheral neurons, one of their functions being to modulate neurotransmitter release. CB(2) receptors are present mainly on immune cells.
R G, Pertwee, R A, Ross
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Characterization of Cannabinoid Receptors

Current Protocols in Pharmacology, 2002
AbstractThis unit describes the use of cannabinoid radioligands in competitive binding assays for determining affinity parameters (IC50,Ki) of unlabeled compounds at transfected CB1 and CB2 receptors expressed in cell lines.Curr. Protoc. Pharmacol. 63:1.26.1‐1.26.10. © 2013 by John Wiley & Sons, Inc.
Richard F, Cox, Vincent, Rash
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The cannabinoid receptors

Prostaglandins & Other Lipid Mediators, 2002
Cannabinoid receptors were named because they have affinity for the agonist delta9-tetrahydrocannabinol (delta9-THC), a ligand found in organic extracts from Cannabis sativa. The two types of cannabinoid receptors, CB1 and CB2. are G protein coupled receptors that are coupled through the Gi/o family of proteins to signal transduction mechanisms that ...
openaire   +2 more sources