Results 161 to 170 of about 28,855 (210)

Cannabinoid Signaling and Autophagy in Oral Disease: Molecular Mechanisms and Therapeutic Implications. [PDF]

Int J Mol Sci
Munkhsaikhan U, Rahman MA, Shasteen A, Ait-Aissa K, Sahyoun AM, Gupta RD, Kassan M, Hoque Apu E, Abidi AH.   +8 more
europepmc   +1 more source

Cannabis‐Based Medicinal Products for Endometriosis: A 2‐Year Prospective Analysis From the UK Medical Cannabis Registry

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 4, August 2026.
ABSTRACT Background Endometriosis affects up to 10% of biological females of reproductive age. Current treatment options are limited and often unsuitable for prolonged use. Cannabis‐based medicinal products (CBMPs) have emerged as an alternative for pain management. Aims To analyse changes in patient‐reported outcome measures (PrOMs), prescribed opioid
Tania Ahmed, Simon Erridge, Evonne Clarke, Katy McLachlan, Ross Coomber, Shelley Barnes, Alia Darweish Medniuk, Rahul Guru, Wendy Holden, Mohammed Sajad, Robert Searle, Azfer Usmani, James J. Rucker, Michael Platt, Mikael H. Sodergren   +14 more
wiley   +1 more source

Computational Characterization of Nabilone-Induced Disruption of the CB2-HER2 Receptor Complex in HER2+ Breast Cancer. [PDF]

Bioinform Biol Insights
Hanane A, Razana Z, Zainab G, Rihab F, Mohammed Walid CE, Mohammed H, Rachid EJ.   +6 more
europepmc   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, Volume 183, Issue 16, Page 4715-4734, August 2026.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Cytotoxic Effects of the Synthetic Cannabinoid, 5F-MDMB-PICA on Human Glioblastoma U87-MG Cells. [PDF]

Int J Med Sci
Alanazi MM, Alasmari F, Algahtani MM, Alhamed AS, Alhosaini KA, Almutairi MM, Alqahtani F, Alanazi WA, Alharbi FN, Alsanie R, Alshehri M, Sari Y.   +11 more
europepmc   +1 more source

Inhibition of peripheral CB1 receptors modulates food intake and metabolic efficiency in obesity independently of the gut–brain vagal axis

British Journal of Pharmacology, Volume 183, Issue 16, Page 4953-4968, August 2026.
Background and Purpose Obesity involves profound disruptions in neuronal circuits, neuroendocrine communication and the endocannabinoid system. While global blockade of cannabinoid CB1 receptors improves metabolism, its clinical use is limited by neuropsychiatric side effects.
Oriane Onimus, Camille de Almeida, Benoit Bertrand, Julien Castel, Nejmeh Mashhour, Anthony Ansoult, Serge Luquet, Giuseppe Gangarossa   +7 more
wiley   +1 more source

Case Report: Oral and topical chronic administration of THC-rich and CBD-rich cannabis oil as palliative care in a rescued horse with open wound, sarcoid and chronic pain. [PDF]

Front Vet Sci
Zamith Cunha R, Kuhn EH, Medeiros JLL, Medeiros GC, Amazonas E.   +4 more
europepmc   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Chronic simultaneous inducible nitric oxide synthase (iNOS) and peripheral cannabinoid CB₁ receptors blockade ameliorates pulmonary hypertension in monocrotaline-induced rat model. [PDF]

Front Pharmacol
Ryszkiewicz P, Remiszewski P, Pędzińska-Betiuk A, Mińczuk K, Baranowska-Kuczko M, Weresa J, Malinowska B.   +6 more
europepmc   +1 more source

Melatonin as a protector against endocrine disruption across tissues: A systematic review

Physiological Reports, Volume 14, Issue 15, August 2026.
Graphical Abstract showing the biological mechanisms by which melatonin protects tissues against endocrine disruption. Abstract Endocrine‐disrupting chemicals (EDCs) are widespread environmental pollutants that interfere with hormonal homeostasis and contribute to multisystem toxicity.
Clenie Isingizwe, Gaudence Ndinganire, Abdullateef Isiaka Alagbonsi   +2 more
wiley   +1 more source