Results 31 to 40 of about 1,264,389 (321)
Numerical simulation of the viral entry into a cell driven by receptor diffusion [PDF]
The present study focuses on the receptor driven endocytosis typical of viral entry into a cell. A locally increased density of receptors at the time of contact between the cell and the virus is necessary in this case. The virus is considered as a substrate with fixed receptors on its surface, whereas the receptors of the host cell are free to move ...
arxiv +1 more source
Increased accuracy of ligand sensing by receptor diffusion on cell surface [PDF]
The physical limit with which a cell senses external ligand concentration corresponds to the perfect absorber, where all ligand particles are absorbed and overcounting of same ligand particles does not occur. Here we analyze how the lateral diffusion of receptors on the cell membrane affects the accuracy of sensing ligand concentration.
arxiv +1 more source
Cell-surface translational dynamics of nicotinic acetylcholine receptors
Synapse efficacy heavily relies on the number of neurotransmitter receptors available at a given time. In addition to the equilibrium between the biosynthetic production, exocytic delivery and recycling of receptors on the one hand, and the endocytic ...
Francisco J Barrantes
doaj +1 more source
Cell surface receptors for CCN proteins [PDF]
The CCN family (CYR61; CTGF; NOV; CCN1-6; WISP1-3) of matricellular proteins in mammals is comprised of six homologous members that play important roles in development, inflammation, tissue repair, and a broad range of pathological processes including fibrosis and cancer.
openaire +3 more sources
Interaction of KSHV with Host Cell Surface Receptors and Cell Entry
Virus entry is a complex process characterized by a sequence of events. Since the discovery of KSHV in 1994, tremendous progress has been made in our understanding of KSHV entry into its in vitro target cells.
Mohanan Valiya Veettil+3 more
doaj +1 more source
Unraveling nanotopography of cell surface receptors [PDF]
ABSTRACTCells communicate with their environment via surface receptors, but nanoscopic receptor organization with respect to complex cell surface morphology remains unclear. This is mainly due to a lack of accessible, robust and high-resolution methods.
Franke, Christian+9 more
openaire +4 more sources
Molecular recognition of paired receptors in the immune system
Cell surface receptors are responsible for regulating cellular function on the front line, the cell membrane. Interestingly, accumulating evidence clearly reveals that the members of cell surface receptor families have very similar extracellular ligand ...
Kimiko eKuroki+4 more
doaj +1 more source
Synthetic mimics of mammalian cell surface receptors: prosthetic molecules that augment living cells [PDF]
This is the publisher's version, also available electronically from http://pubs.rsc.org/en/Content/ArticleLanding/2005/OB/b509866a#!divAbstractSpecific receptors on the surface of mammalian cells actively internalize cell-impermeable ligands by receptor ...
Peterson, Blake R.
core +1 more source
Anterograde Trafficking of CXCR4 and CCR2 Receptors in a Prostate Cancer Cell Line
Background: Most prostate cancer-related deaths result from metastasis. CXCR4 and CCR2 are known to govern cellular processes resulting in cell migration, proliferation and survival.
Kelsie Gillies+3 more
doaj +1 more source
Tumor necrosis factor-associated ligand inducing apoptosis (TRAIL) induces apoptosis through the death receptors (DRs) 4 and 5 expressed on the cell surface. Upon ligand stimulation, death receptors are rapidly internalized through clathrin-dependent and
Artem A. Artykov+8 more
doaj +1 more source