Results 31 to 40 of about 16,141 (203)

Neurobiological background for the development of new drugs in schizophrenia

, 2011
Psychopharmacology of schizophrenia has remained static for many years because the mechanisms explored have been basically monoaminergics, primarily focused toward the modification of dopaminergic function and, later on, serotonergic.
Álamo González, C, Francisco López-Muñoz, López-Muñoz, F., Cecilio Álamo   +3 more
core   +1 more source

Pancreatic secretory response to feeding in the calf: CCK-A receptors, but not CCK-B/gastrin receptors are involved

, 2000
In bovine species, as in human, the pancreas predominantly expresses cholecystokinin-B (CCK-B)/gastrin receptors. However, the role of this receptor in the regulation of meal-stimulated pancreatic enzyme release has not been determined.
Martine Gestin, Gwenola Le Dréan, Paul Guilloteau, Christine Bernard, Véronique Romé, Jean-Alain Chayvialle, Isabelle Le Huërou-Luron, Daniel Fourmy   +7 more
core   +1 more source

Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion. [PDF]

PLoS Pathogens, 2013
Gastrointestinal infection is often associated with hypophagia and weight loss; however, the precise mechanisms governing these responses remain poorly defined.
John J Worthington, Linda C Samuelson, Richard K Grencis, John T McLaughlin   +3 more
doaj   +1 more source

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Expression of cholecystokinin A receptors in neurons innervating the rat stomach and intestine

, 1999
Background and Aims: Two distinct receptors, cholecystokinin (CCK)-A and CCK-B, mediate CCK effects in the digestive system. The aim of this study was to elucidate the cellular sites of expression of CCK-A receptor in the rat stomach and small intestine.
Kuntz SM, Pham T, Raybould H.E., Miller LJ, Walsh JH, Sternini C, DE GIORGIO, Roberto, Reeve JR, Wong H   +8 more
core   +1 more source

Gastrin Exerts Pleiotropic Effects on Human Melanoma Cell Biology

Neoplasia: An International Journal for Oncology Research, 2005
The effects of gastrin (G17) on the growth and migration factors of four human melanoma cell lines (HT-144, C32, G-361, and SKMEL-28) were investigated. The expression patterns of cholecystokinin (CCK)A CCKB, and CCKC gastrin receptors were investigated ...
Véronique Mathieu, Tatjana Mijatovic, Marc van Damme, Robert Kiss   +3 more
doaj   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Cholecystokinin receptor-1 mediates the inhibitory effects of exogenous cholecystokinin octapeptide on cellular morphine dependence

BMC Neuroscience, 2012
Background Cholecystokinin octapeptide (CCK-8), the most potent endogenous anti-opioid peptide, has been shown to regulate the processes of morphine dependence.
Wen Di, Ma Chun-ling, Zhang Ya-jing, Meng Yan-xin, Ni Zhi-yu, Li Shu-jin, Cong Bin   +6 more
doaj   +1 more source

Advantages of low‐glycaemic‐index carbohydrates in regulating glycaemic response of energy bar: A review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Energy bars are widely consumed functional foods among athletes and physically active consumers who require convenient sources of sustained energy. Their carbohydrate composition, particularly the type and ratio of digestible sugars such as glucose, fructose and sucrose, strongly influences glycaemic index (GI), postprandial blood glucose ...
Raju Sasikumar, Ayush Gupta, Selva Kumar T, Kaviarasu Ganesan, Sheena Haorongbam, Ravikumar Rajarathinam, Sandeep Janghu, Sandeep Kumar Panda, Amit K. Jaiswal   +8 more
wiley   +1 more source

Review: Free fatty acid receptors: emerging targets for treatment of diabetes and its complications

Therapeutic Advances in Endocrinology and Metabolism, 2010
Fatty acids (FAs) are important as metabolic substrates and as structural components of biological membranes. However, they also function as signalling molecules.
R. Lee Kennedy, Venkat Vangaveti, Ghassan Jarrod, Venkatesh Shashidhar, Venkatesh Shashidhar, Bernhard T. Baune   +5 more
doaj   +1 more source