Results 251 to 260 of about 2,364,275 (293)

Cholinergic receptors in insects

Trends in Biochemical Sciences, 1979
Abstract It has been suggested that cholinergic receptors in insects are neither nicotinic nor muscarinic but of a mixed nature, and hence differ from ‘classic' vertebrate receptors. However, recent evidence indicates that insects also contain distinct nicotinic and muscarinic binding-sites with properties resembling those of vertebrate receptors. The
openaire   +2 more sources

Cholinerge Rezeptoren und Anästhesie

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie, 1992
Postsynaptic chemically controlled ion channels are a possible location for the action of anaesthetics. The nicotinic acetylcholine receptor (AcChoR) is a member of a superfamily of chemically controlled ion channels, which have a large number of structural similarities in common.
Keith W. Miller, Tonner Ph
openaire   +3 more sources

Cholinergic Receptor Isolation

1981
The isolation of specific cholinergic bindin protein (acetylcholine receptor = AChR) has been achieved successfully by numerous research groups (1-4, 7-9, 11, 12). The ideal source for such preparations was the electric organ of several species of Torpedo.
Peter G. Waser, Gaetano Riggio, A. A. Hofmann, W. H. Hopff   +3 more
openaire   +2 more sources

Chapter 5 Cholinergic innervation and receptors in the cerebellum

1997
We have studied the source and ultrastructural characteristics of ChAT-immunoreactive fibers in the cerebellum of the rat, and the distribution of muscarinic and nicotinic receptors in the cerebellum of the rat, rabbit, cat and monkey, in order to define which of the cerebellar afferents may use ACh as a neurotransmitter, what target structures are ...
Romeo Caffé, Jan Voogd, Enrico Mugnaini, Dick Jaarsma, Allan I. Levey, Constantino Cozzari, Tom J. H. Ruigrok   +6 more
openaire   +3 more sources

Cholinergic receptors in the Aplysia gill

Journal of Neurobiology, 1984
AbstractAcetylcholine has been suggested as a neurotransmitter released in the Aplysia gill by peripheral afferents of central neurons and by peripheral neurons within the gill. The perfused gill, isolated from the abdominal ganglion, was examined. At concentrations greater than 1 μM, acetylcholine elicited a slowly developing tonic contraction of the ...
Samuel Weiss, Samuel Weiss, Jeffrey I. Goldberg, Jon Edstrom, Ken Lukowiak   +4 more
openaire   +3 more sources

The nicotinic cholinergic receptor: A theoretical model

Journal of Neuroscience Research, 1996
Based on published affinity-labeling and mutagenesis experiments describing the effect of changes in specific amino acids in molecular biological studies on the nicotinic acetylcholinergic receptor (nAChR), we have identified 12 amino acids which are important in functioning at the nicotinic cholinergic receptor.
Kenny B. Lipkowitz, M. H. Aprison, E. Galvez-Ruano   +2 more
openaire   +3 more sources

Sex and Gender Differences in the Brain Cholinergic System and in the Response to Therapy of Alzheimer Disease with Cholinesterase Inhibitors.

Current Alzheimer Research, 2018
This review has two aims. First, to examine whether or not sex and gender may influence the brain cholinergic system in animals and in humans. Second, to examine the available evidence of sexually dimorphic response to the therapeutic and toxic effects ...
E. Giacobini, G. Pepeu
semanticscholar   +1 more source

Muscarinic cholinergic receptor heterogeneity

Trends in Neurosciences, 1982
Abstract The relatively recent application of receptor binding techniques to muscarinic receptor pharmacology has provided new data that generally confirm classical ideas about agonist-receptor interactions and competitive antagonism. However, additional information regarding muscarinic receptor heterogeneity has been provided through [ 3 H]ligand ...
William R. Roeske, Frederick J. Ehlert, Henry I. Yamamura   +2 more
openaire   +2 more sources

Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation.

Science, 1985
Cerebral cortex samples from patients with Alzheimer's disease and from rats after experimental cholinergic denervation of the cerebral cortex exhibited reductions in the presynaptic marker choline acetyltransferase activity and in the number of M2 ...
D. Mash, D. D. Flynn, L. Potter
semanticscholar   +1 more source

Cholinergic Systems and Multiple Cholinergic Receptors in Ocular Tissues

Journal of Ocular Pharmacology and Therapeutics, 1985
Acetylcholine (ACh), choline acetyltransferases and cholinesterases occur in cornea, iris-ciliary body complex and retina of several vertebrates. In cornea, ACh may serve as a sensory transmitter as well as a local hormone, the function of which is not delineated.
openaire   +3 more sources