Results 231 to 240 of about 1,111,234 (301)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Platelets link coagulation and complement in regulating murine placental vascular development. [PDF]

J Clin Invest
Smid A, Schumann L, Oleshko O, Peters-Bernard U, Flächsig-Schulz K, Whitehead M, Arndt E, Brand K, Werwitzke S, Klos A, Morgan BP, Zelek WM, Tiede A, Abeln M.   +13 more
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

The prefrontal cortex as a target of HIV-1 neurotoxicity: molecular mechanisms of viral protein-mediated neurodegeneration and executive dysfunction. [PDF]

Front Cell Neurosci
Honsa ES.
europepmc   +1 more source

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun, Shaun G. Hong, Na Young Park, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

Neutrophil extracellular traps and acute kidney injury: a narrative review. [PDF]

Front Immunol
Zhou S, Lu J, Zheng J, Liao Y, Chen S, Wu H, Xiong J, Li X, Tang Y.   +8 more
europepmc   +1 more source

Pathogenic properties of myasthenia gravis AChR autoantibodies associate with clinical response to efgartigimod. [PDF]

J Neurol Neurosurg Psychiatry
Khani-Habibabadi F, Verhamme FM, Moshir M, Casneuf T, Rao VTS, Steeland S, Ulrichts P, Pham MC, Nowak RJ, Roy B, O'Connor KC.   +10 more
europepmc   +1 more source

Protective role of complement signaling in Kawasaki disease vasculitis. [PDF]

JCI Insight
Atici AE, Kocatürk B, Ross BL, Aubuchon EA, Porritt RA, Carvalho TT, Namba T, Lee Y, Noval Rivas M, Arditi M.   +9 more
europepmc   +1 more source

Immunity: defense against infections essential for all living organisms. [PDF]

Front Immunol
Akula S, Wernersson S, Hellman L.
europepmc   +1 more source

Human Antibody Isotypes, Subclasses, Allotypes and Fc Biology: Clinical Implications in Infectious Diseases, Autoimmunity, and Cancer. [PDF]

Pharmaceuticals (Basel)
Gautam S, Singh S, Thakkar V, Joshi D, Kumar S.   +4 more
europepmc   +1 more source