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Complement receptor structure and function
Immunology Today, 1985Membrane complement receptors (CRs) are now recognized as important cell-bound components of the complement system and research into the structure and function of complement receptors is one of the main thrusts of current complement research.
John P. Atkinson, Gordon D. Ross
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The Chemistry and Biology of Complement Receptors
Springer Seminars in Immunopathology, 1984Activation of the complement system gives rise to a number of molecular species which can interact with host-derived cells and regulate their function. This interaction is mediated through distinct cell surface complement receptors, and receptor engagement produces biologic responses which can either modulate host defense reactions or enhance ...
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Complement Receptors and B Lymphocytes
Critical Reviews™ in Immunology, 2004Most of the biological processes depend on cell-to-cell and protein-to-cell interactions, which take place through receptors present on the cell surface. Various physiological systems are linked by such interactions, as is the case for innate and adaptative immune response.
Marie-Bernadette Villiers+3 more
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Complement Receptor 2 and Autoimmunity
2003Complement receptor 2 (CR2/CD21) plays a major role in the immune response by linking innate and adaptive immunity to foreign pathogens and proteins. In addition, several lines of evidence strongly support a role for CR2 in the maintenance of tolerance to self-antigens.
Susan A. Boackle, V.M. Holers
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Complement receptors in HIV infection
Immunological Reviews, 1997SummaryThe complement system plays an important role in the antimicrobial defense of the organism. Its components recognize a large variety of pathogens and target them for destruction, either directly by formation of a membrane attack complex or indirectly by recruiting phagocytic cells.
Laco Kacani+2 more
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Regulation of Macrophage Functions by Complement, Complement Receptors, and IgG-Fc Receptors [PDF]
Membrane receptors provide the essential recognition function required for control of macrophage responses to changes in their cellular environment. Considering the complexity and number of different functions performed by macrophages, it is likely that only a small proportion of the total number of different types of receptors are presently known ...
Simon L. Newman, Gordon D. Ross
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The complement system: an unexpected role in synaptic pruning during development and disease.
Annual Review of Neuroscience, 2012An unexpected role for the classical complement cascade in the elimination of central nervous system (CNS) synapses has recently been discovered. Complement proteins are localized to developing CNS synapses during periods of active synapse elimination ...
A. Stephan, B. Barres, B. Stevens
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Journal of Immunology, 1993
We have examined macrophage receptors that mediate phagocytosis of virulent strains (Erdman and H37Rv) and an attenuated strain (H37Ra) of the intracellular pathogen, Mycobacterium tuberculosis.
L. Schlesinger
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We have examined macrophage receptors that mediate phagocytosis of virulent strains (Erdman and H37Rv) and an attenuated strain (H37Ra) of the intracellular pathogen, Mycobacterium tuberculosis.
L. Schlesinger
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Emerging Insights into the Structure and Function of Complement C5a Receptors.
TIBS -Trends in Biochemical Sciences. Regular ed, 2020Shubhi Pandey+4 more
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