Results 31 to 40 of about 3,062,816 (304)
Journal of Investigative Dermatology, 1990 CR2, a membrane glycoprotein, is one of a number of cell-surface proteins which bind activation and processing fragments of the complement system. CR2, which is found on normal B lymphocytes, follicular dendritic cells in lymphoid organs, and epithelial cells, interacts preferentially with C3dg, the terminal activation/processing fragment of the third ...
B M Bradt +3 more
openaire +3 more sources
Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses
Viruses, 2021 The complement system represents a crucial part of innate immunity. It contains a diverse range of soluble activators, membrane-bound receptors, and regulators.
Valarmathy Murugaiah +5 more
doaj +1 more source
CR3 is the dominant phagocytotic complement receptor on human dendritic cells. [PDF]
, 2013 Dendritic cells (DCs) play a decisive role in immunity; they interact with various pathogens via several pattern recognition and different opsonophagocytotic receptors, including Fc- and complement-receptors. beta2-integrins, including complement
Abram +56 more
core +1 more source
Neutrophil chemoattractant receptors in health and disease: double-edged swords
Cellular & Molecular Immunology, 2020 Neutrophils are frontline cells of the innate immune system. These effector leukocytes are equipped with intriguing antimicrobial machinery and consequently display high cytotoxic potential. Accurate neutrophil recruitment is essential to combat microbes
Mieke Metzemaekers, M. Gouwy, P. Proost
semanticscholar +1 more source
Role of Complement and Histones in Sepsis
Frontiers in Medicine, 2020 The wide use of the mouse model of polymicrobial sepsis has provided important evidence for events occurring in infectious sepsis involving septic mice and septic humans.
Firas S. Zetoune, Peter A. Ward
doaj +1 more source
Revising Berg-Purcell for finite receptor kinetics [PDF]
, 2021 From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv +1 more source
Safety and Health at Work, 2017 Background: There are a million ragpickers in India who gather and trade recyclable municipal solid wastes materials for a living. The objective of this study was to examine whether their occupation adversely affects their immunity. Methods: Seventy-four
Nandan K. Mondal +7 more
doaj +1 more source
Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]
, 2015 Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien +6 more
core +2 more sources
Neuropilin-1 Acts as a Receptor for Complement Split Products
Frontiers in Immunology, 2019 Complement split products (CSPs), such as the fragments C4d and C3d, which are generated as a consequence of complement regulatory processes, are established markers for disease activity in autoimmunity or antibody-mediated graft rejection.
Claire Battin +9 more
doaj +1 more source
Anaphylatoxins spark the flame in early autoimmunity
Frontiers in Immunology, 2022 The complement system (CS) is an ancient and highly conserved part of the innate immune system with important functions in immune defense. The multiple fragments bind to specific receptors on innate and adaptive immune cells, the activation of which ...
Jovan Schanzenbacher +3 more
doaj +1 more source