Results 11 to 20 of about 18,708 (168)

The Local Neuropeptide System of Keratinocytes

open access: yesBiomedicines, 2021
Neuropeptides have been known for over 50 years as chemical signals in the brain. However, it is now well established that the synthesis of this class of peptides is not restricted to neurons. For example, human skin not only expresses several functional
Nicola Cirillo
doaj   +1 more source

The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response

open access: yesВавиловский журнал генетики и селекции, 2021
Stress is an essential part of everyday life. The neuropeptide corticotropin-releasing hormone (CRH, also called CRF and corticoliberin) plays a key role in the integration of neuroendocrine, autonomic and behavioral responses to stress.
E. V. Sukhareva
doaj   +1 more source

Transcriptional regulation of corticotropin-releasing hormone gene in stress response

open access: yesIBRO Reports, 2018
As a central player of the hypothalamic-pituitary-adrenal (HPA) axis, the corticotropin -releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) determine the state of HPA axis and play a key role in stress response.
Jiang-Ning Zhou, Hui Fang
doaj   +1 more source

Transcriptome of the female synganglion of the black-legged tick Ixodes scapularis (Acari: Ixodidae) with comparison between Illumina and 454 systems. [PDF]

open access: yesPLoS ONE, 2014
Illumina and 454 pyrosequencing were used to characterize genes from the synganglion of female Ixodes scapularis. GO term searching success for biological processes was similar for samples sequenced by both methods.
Noble Egekwu   +3 more
doaj   +1 more source

Literature-Based Discovery to Elucidate the Biological Links between Resistant Hypertension and COVID-19

open access: yesBiology, 2023
Multiple studies have reported new or exacerbated persistent or resistant hypertension in patients previously infected with COVID-19. We used literature-based discovery to identify and prioritize multi-scalar explanatory biology that relates resistant ...
David Kartchner   +7 more
doaj   +1 more source

Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction [PDF]

open access: yesJournal of Experimental Medicine, 2017
Heart failure occurs when the heart is unable to effectively pump blood and maintain tissue perfusion. Despite numerous therapeutic advancements over previous decades, the prognosis of patients with chronic heart failure remains poor, emphasizing the need to identify additional pathophysiological factors.
Takuma Tsuda   +15 more
openaire   +3 more sources

Mechanism of Anticonvulsant Action of ACTH

open access: yesPediatric Neurology Briefs, 2001
The hypothesis that systemic or intraventricular administration of corticotropin (ACTH) acts directly on limbic neurons to modulate corticotropin-releasing hormone (CRH) gene expression, independently of adrenal stimulation, was tested and confirmed in ...
J Gordon Millichap
doaj   +1 more source

The Role of Corticotropin-Releasing Hormone at Peripheral Nociceptors: Implications for Pain Modulation

open access: yesBiomedicines, 2020
Peripheral nociceptors and their synaptic partners utilize neuropeptides for signal transmission. Such communication tunes the excitatory and inhibitory function of nociceptor-based circuits, eventually contributing to pain modulation.
Haiyan Zheng   +3 more
doaj   +1 more source

HYPOTHALAMIC NEUROHORMONES AND IMMUNE RESPONSES

open access: yesFrontiers in Integrative Neuroscience, 2013
The aim of this review is to provide a comprehensive examination of the current literature describing the neural-immune interactions, with emphasis on the most recent findings of the effects of neurohormones on immune system.
J. Luis eQuintanar, Irene eGuzmán-Soto
doaj   +1 more source

Expression of Corticotropin-Releasing Hormone and Its Receptors May Be Associated With Survival Rate in Pancreatic Cancer

open access: yesGastro Hep Advances, 2023
Background and Aims: Corticotropin-releasing hormone (CRH) is a major regulator of the stress response to internal and external factors. CRH and its receptors (CRHR1 and CRHR2) are expressed in the central nervous system and some cancer cells, suggesting
Naoko Sato   +11 more
doaj   +1 more source

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