Results 11 to 20 of about 19,155 (223)
Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin [PDF]
FEBS Letters, 1995 Evidence is provided that human skin, the largest body organ exposed to multiple stressors, expresses proopiomelanocortin (POMC), corticotropin releasing hormone (CRH) and CRH‐receptor (CRHR) genes in vivo. In vitro studies show that POMC and CRHR mRNAs are transcribed in melanocytes, cells derived from the neural crest, and in keratinocytes, cells ...
Slominski, A. +5 more
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Corticotropin-releasing hormone receptor antagonists [PDF]
European Journal of Endocrinology, 2006 Corticotropin-releasing hormone (CRH), CRH-related peptides, and CRH receptors play major roles in coordinating the behavioral, endocrine, autonomic, and immune responses to stress. The wide influence of the CRH system on physiological processes in both brain and periphery implicates the respective peptides in the pathophysiology of numerous disorders ...
Zoumakis, E. +2 more
openaire +2 more sources
Scientific Reports, 2023 Chronic immobilization stress plays a key role in several neuropsychiatric disorders. This investigation assessed the possible ameliorative effect of chia seed oil (CSO) against the neurodisturbance-induced in rats by chronic immobilization.
Norhan E. Khalifa +7 more
doaj +1 more source
The Local Neuropeptide System of Keratinocytes
Biomedicines, 2021 Neuropeptides have been known for over 50 years as chemical signals in the brain. However, it is now well established that the synthesis of this class of peptides is not restricted to neurons. For example, human skin not only expresses several functional
Nicola Cirillo
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Transcriptional regulation of corticotropin-releasing hormone gene in stress response
IBRO Reports, 2018 As a central player of the hypothalamic-pituitary-adrenal (HPA) axis, the corticotropin -releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) determine the state of HPA axis and play a key role in stress response.
Jiang-Ning Zhou, Hui Fang
doaj +1 more source
Transcriptome of the female synganglion of the black-legged tick Ixodes scapularis (Acari: Ixodidae) with comparison between Illumina and 454 systems. [PDF]
PLoS ONE, 2014 Illumina and 454 pyrosequencing were used to characterize genes from the synganglion of female Ixodes scapularis. GO term searching success for biological processes was similar for samples sequenced by both methods.
Noble Egekwu +3 more
doaj +1 more source
Mechanism of Anticonvulsant Action of ACTH
Pediatric Neurology Briefs, 2001 The hypothesis that systemic or intraventricular administration of corticotropin (ACTH) acts directly on limbic neurons to modulate corticotropin-releasing hormone (CRH) gene expression, independently of adrenal stimulation, was tested and confirmed in ...
J Gordon Millichap
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Biology, 2023 Multiple studies have reported new or exacerbated persistent or resistant hypertension in patients previously infected with COVID-19. We used literature-based discovery to identify and prioritize multi-scalar explanatory biology that relates resistant ...
David Kartchner +7 more
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HYPOTHALAMIC NEUROHORMONES AND IMMUNE RESPONSES
Frontiers in Integrative Neuroscience, 2013 The aim of this review is to provide a comprehensive examination of the current literature describing the neural-immune interactions, with emphasis on the most recent findings of the effects of neurohormones on immune system.
J. Luis eQuintanar, Irene eGuzmán-Soto
doaj +1 more source
Gastro Hep Advances, 2023 Background and Aims: Corticotropin-releasing hormone (CRH) is a major regulator of the stress response to internal and external factors. CRH and its receptors (CRHR1 and CRHR2) are expressed in the central nervous system and some cancer cells, suggesting
Naoko Sato +11 more
doaj +1 more source